Phenominer Database Results (124 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
PXO2/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 11 74.1 mg/dl 1.8 5.97 enzymatic cholesterol assay 0.0 0 97226 1858
PXO7-1/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 8 51.7 mg/dl 1.0 2.83 enzymatic cholesterol assay 0.0 0 97213 1858
PXO9/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 9 20.88 mg/dl 1.08 3.24 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97293 1858
PXO3-1/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 10 0.03 mg/dl 0.0 0.01 enzymatic cholesterol assay 0.0 0 97349 1858
PXO8-1/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 10 0.06 mg/dl 0.01 0.03 enzymatic cholesterol assay 0.0 0 97352 1858
PXO5-1/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 11 0.16 mg/dl 0.04 0.13 enzymatic cholesterol assay 0.0 0 97357 1858
PXO6-1/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 10 31.15 mg/dl 1.38 4.36 enzymatic cholesterol assay 0.0 0 97301 1858
PXO6-3/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 10 43.66 mg/dl 1.74 5.5 enzymatic cholesterol assay 0.0 0 97308 1858
PXO5-1/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 11 10.45 mg/dl 1.44 4.78 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97281 1858
PXO3-2/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 9 10.72 mg/dl 0.65 1.95 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97282 1858
SHR.BN-(D8Mit5-D8Mgh6)/Ipcv blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 13 21.56 mg/dl 0.61 2.2 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97294 1858
PXO4/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 9 3.43 mg/dl 0.4 1.2 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97265 1858
PXO10/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 12 7.8 mg/dl 0.44 1.52 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97274 1858
WKY liver cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. liver cholesterol amount male 0 days 7 3.92 mg/g 0.24 0.63 enzymatic cholesterol assay 0.0 0 98894 2178
HTG liver cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. liver cholesterol amount male 0 days 7 3.71 mg/g 0.13 0.35 enzymatic cholesterol assay 0.0 0 98896 2178
PXO1/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 11 0.13 mg/dl 0.02 0.07 enzymatic cholesterol assay 0.0 0 97356 1858
PXO9/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 9 32.9 mg/dl 2.96 8.88 enzymatic cholesterol assay 0.0 0 97303 1858
BXH2/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 18 15.68 mg/dl 1.08 4.58 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97289 1858
PXO7-1/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 8 2.91 mg/dl 0.25 0.71 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97264 1858
HTG plasma very low density lipoprotein cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood VLDL cholesterol amount male 0 days 7 4.25 mg/dl 1.16 3.06 enzymatic cholesterol assay 0.0 0 98908 2178
HTG plasma low density lipoprotein cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood LDL cholesterol amount male 0 days 7 14.67 mg/dl 1.54 4.09 enzymatic cholesterol assay 0.0 0 98912 2178
LEW/OlaHsd serum total cholesterol level fasting (for 16 hours) Bonne AC, et al., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9. blood cholesterol amount male 49 days 6 98.84 mg/dl 2.05 5.02 enzymatic cholesterol assay 0 12630 271
SHR/OlaIpcv liver cholesterol level controlled olive oil content diet (5 %) (for 28 days) then controlled cholesterol content diet (2 %) (for 28 days) Bottger A, et al., Biochem Biophys Res Commun 1998 May 8;246(1):272-5. liver cholesterol amount not specified 77 days 0 38.47 mg/g enzymatic cholesterol assay 0.0 0 cholesterol measurement test umole/g, liver cholesterol measurement 68976 1036
BN-Lx/Cub liver cholesterol level controlled olive oil content diet (5 %) (for 28 days) then controlled cholesterol content diet (2 %) (for 28 days) Bottger A, et al., Biochem Biophys Res Commun 1998 May 8;246(1):272-5. liver cholesterol amount not specified 77 days 0 70.99 mg/g enzymatic cholesterol assay 0.0 0 cholesterol measurement test umole/g, liver cholesterol measurement 68977 1036
SHR.BN-(D10Mgh3-D10Rat85)/Ipcv liver triglyceride level controlled cholesterol content diet (2 %) (for 28 days) Pravenec M, et al., Hypertension. 2008 Jan;51(1):148-53. Epub 2007 Dec 10. liver triglyceride amount male 77 days 8 24.87 mg/g 1.33 3.75 enzymatic cholesterol assay 0.0 0 tissue triglyceride measurement test liver triglyceride, umol/g 68990 1039
PXO5-2/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 10 0.42 mg/dl 0.05 0.16 enzymatic cholesterol assay 0.0 0 97360 1858
PXO1/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 11 27.54 mg/dl 1.8 5.97 enzymatic cholesterol assay 0.0 0 97299 1858
PXO6-1/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 10 0.81 mg/dl 0.12 0.38 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97240 1858
PXO5-2/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 10 10.68 mg/dl 0.89 2.81 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97275 1858
PXO4/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 9 66.5 mg/dl 1.3 3.9 enzymatic cholesterol assay 0.0 0 97225 1858
SHR.BN-(D8Mit5-D8Mgh6)/Ipcv blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 13 53.7 mg/dl 1.2 4.33 enzymatic cholesterol assay 0.0 0 97216 1858
PXO9/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 9 60.9 mg/dl 2.0 6.0 enzymatic cholesterol assay 0.0 0 97221 1858
PXO5-2/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 10 17.35 mg/dl 0.72 2.28 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97290 1858
PXO10/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 12 19.44 mg/dl 0.68 2.36 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97291 1858
PXO6-3/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 10 11.02 mg/dl 0.62 1.96 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97284 1858
BXH2/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 18 4.82 mg/dl 0.67 2.84 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97268 1858
PXO3-2/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 9 0.02 mg/dl 0.0 0.01 enzymatic cholesterol assay 0.0 0 97347 1858
WKY plasma total cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood cholesterol amount male 0 days 7 66.02 mg/dl 3.86 10.22 enzymatic cholesterol assay 0.0 0 98903 2178
WKY plasma low density lipoprotein cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood LDL cholesterol amount male 0 days 7 7.72 mg/dl 0.77 2.04 enzymatic cholesterol assay 0.0 0 98911 2178
SD-Lepem1Sage+/+ liver cholesterol level control condition (for 126 days) D'souza AM, et al., Endocrinology. 2014 Apr;155(4):1268-79. doi: 10.1210/en.2013-1523. Epub 2014 Jan 27. liver cholesterol amount female 126 days 6 1.83 mg/g 0.18 0.45 enzymatic cholesterol assay 0.0 0 104448 2949
SD-Lepem1Sage-/- liver cholesterol level control condition (for 126 days) D'souza AM, et al., Endocrinology. 2014 Apr;155(4):1268-79. doi: 10.1210/en.2013-1523. Epub 2014 Jan 27. liver cholesterol amount female 126 days 6 2.54 mg/g 0.28 0.69 enzymatic cholesterol assay 0.0 0 104449 2949
LEW/OlaHsd serum total cholesterol level controlled olive oil content diet (5 %) (for 28 days) and controlled cholesterol content diet (2 %) (for 28 days) then fasting (for 16 hours) Bonne AC, et al., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9. blood cholesterol amount male 77 days 6 174.52 mg/dl 22.86 55.98 enzymatic cholesterol assay 0 12631 271
SHR/OlaIpcv liver triglyceride level controlled cholesterol content diet (2 %) (for 28 days) Pravenec M, et al., Hypertension. 2008 Jan;51(1):148-53. Epub 2007 Dec 10. liver triglyceride amount male 77 days 7 23.36 mg/g 0.88 2.34 enzymatic cholesterol assay 0.0 0 tissue triglyceride measurement test liver triglyceride, umol/g 68991 1039
BXH2/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 18 48.7 mg/dl 1.6 6.79 enzymatic cholesterol assay 0.0 0 97211 1858
PXO3-2/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 9 58.5 mg/dl 2.7 8.1 enzymatic cholesterol assay 0.0 0 97219 1858
HTG liver cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. liver cholesterol amount male 0 days 7 7.57 mg/g 0.62 1.65 enzymatic cholesterol assay 0.0 0 98897 2178
WKY plasma low density lipoprotein cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood LDL cholesterol amount male 0 days 7 10.04 mg/dl 1.16 3.06 enzymatic cholesterol assay 0.0 0 98910 2178
PXO4/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 9 19.47 mg/dl 1.06 3.18 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97292 1858
PXO9/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 9 7.02 mg/dl 1.08 3.24 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97272 1858
PXO4/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 9 43.61 mg/dl 0.92 2.76 enzymatic cholesterol assay 0.0 0 97307 1858
PXO3-2/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 9 46.2 mg/dl 2.14 6.42 enzymatic cholesterol assay 0.0 0 97312 1858
BC/CpbU serum total cholesterol level controlled olive oil content diet (5 %) (for 28 days) and controlled cholesterol content diet (2 %) (for 28 days) then fasting (for 16 hours) Bonne AC, et al., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9. blood cholesterol amount male 77 days 6 93.82 mg/dl 5.83 14.29 enzymatic cholesterol assay 0 12627 271
BC/CpbU serum total cholesterol level controlled olive oil content diet (5 %) (for 28 days) and controlled cholesterol content diet (2 %) (for 28 days) then fasting (for 16 hours) Bonne AC, et al., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9. blood cholesterol amount female 77 days 6 148.26 mg/dl 9.46 23.17 enzymatic cholesterol assay 0 12629 271
PXO6-3/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 10 1.36 mg/dl 0.14 0.44 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97260 1858
PXO3-1/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 10 2.26 mg/dl 0.17 0.54 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97263 1858
SHR.BN-(D8Mit5-D8Mgh6)/Ipcv blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 13 6.85 mg/dl 0.53 1.91 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97271 1858
PXO6-2/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 8 0.02 mg/dl 0.01 0.03 enzymatic cholesterol assay 0.0 0 97346 1858
PXO3-1/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 10 10.28 mg/dl 0.28 0.89 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97280 1858
PXO8-2/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 13 61.0 mg/dl 1.3 4.69 enzymatic cholesterol assay 0.0 0 97222 1858
PXO6-2/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 8 61.7 mg/dl 2.6 7.35 enzymatic cholesterol assay 0.0 0 97223 1858
PXO10/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 12 49.4 mg/dl 2.0 6.93 enzymatic cholesterol assay 0.0 0 97212 1858
PXO5-2/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 10 60.6 mg/dl 1.4 4.43 enzymatic cholesterol assay 0.0 0 97220 1858
PXO7-1/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 8 12.24 mg/dl 0.39 1.1 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97286 1858
PXO9/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 9 0.08 mg/dl 0.02 0.06 enzymatic cholesterol assay 0.0 0 97354 1858
SHR.BN-(D8Mit5-D8Mgh6)/Ipcv blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 13 25.67 mg/dl 0.67 2.42 enzymatic cholesterol assay 0.0 0 97298 1858
PXO5-1/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 11 36.37 mg/dl 1.47 4.88 enzymatic cholesterol assay 0.0 0 97304 1858
PXO2/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 11 46.23 mg/dl 1.97 6.53 enzymatic cholesterol assay 0.0 0 97313 1858
HTG plasma total cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood cholesterol amount male 0 days 7 65.64 mg/dl 3.09 8.17 enzymatic cholesterol assay 0.0 0 98905 2178
SD-Lepem1Sage+/+ liver cholesterol level control condition (for 126 days) D'souza AM, et al., Endocrinology. 2014 Apr;155(4):1268-79. doi: 10.1210/en.2013-1523. Epub 2014 Jan 27. liver cholesterol amount male 126 days 6 2.05 mg/g 0.23 0.56 enzymatic cholesterol assay 0.0 0 104446 2949
PXO7-1/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 8 0.02 mg/dl 0.01 0.03 enzymatic cholesterol assay 0.0 0 97348 1858
PXO8-2/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 13 0.05 mg/dl 0.01 0.04 enzymatic cholesterol assay 0.0 0 97351 1858
BXH2/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 18 28.01 mg/dl 2.08 8.82 enzymatic cholesterol assay 0.0 0 97300 1858
PXO8-1/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 10 3.44 mg/dl 0.25 0.79 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97266 1858
PXO2/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 11 5.0 mg/dl 0.51 1.69 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97269 1858
PXO5-1/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 11 53.3 mg/dl 2.4 7.96 enzymatic cholesterol assay 0.0 0 97214 1858
HTG plasma total cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood cholesterol amount male 0 days 7 60.62 mg/dl 3.09 8.17 enzymatic cholesterol assay 0.0 0 98904 2178
HTG plasma high density lipoprotein cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood HDL cholesterol amount male 0 days 7 29.34 mg/dl 1.93 5.11 enzymatic cholesterol assay 0.0 0 98917 2178
SHR/OlaIpcv liver cholesterol level control condition Bottger A, et al., Biochem Biophys Res Commun 1998 May 8;246(1):272-5. liver cholesterol amount not specified 77 days 0 2.9 mg/g enzymatic cholesterol assay 0.0 0 cholesterol measurement test umole/g, liver cholesterol measurement 68974 1036
SHR.BN-(D10Mgh3-Srebf1)/Ipcv liver triglyceride level controlled cholesterol content diet (2 %) (for 28 days) Pravenec M, et al., Hypertension. 2008 Jan;51(1):148-53. Epub 2007 Dec 10. liver triglyceride amount male 77 days 5 33.54 mg/g 2.48 5.54 enzymatic cholesterol assay 0.0 0 tissue triglyceride measurement test liver triglyceride, umol/g 68992 1039
PXO3-1/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 10 53.7 mg/dl 1.3 4.11 enzymatic cholesterol assay 0.0 0 97215 1858
PXO1/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 11 57.4 mg/dl 1.4 4.64 enzymatic cholesterol assay 0.0 0 97218 1858
PXO4/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 9 0.03 mg/dl 0.01 0.03 enzymatic cholesterol assay 0.0 0 97350 1858
PXO5-2/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 10 32.16 mg/dl 1.52 4.81 enzymatic cholesterol assay 0.0 0 97302 1858
PXO3-1/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 10 41.19 mg/dl 1.06 3.35 enzymatic cholesterol assay 0.0 0 97306 1858
PXO8-2/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 13 45.31 mg/dl 1.29 4.65 enzymatic cholesterol assay 0.0 0 97309 1858
PXO6-2/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 8 46.13 mg/dl 1.76 4.98 enzymatic cholesterol assay 0.0 0 97311 1858
PXO1/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 11 22.37 mg/dl 1.06 3.52 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97295 1858
PXO7-1/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 8 36.57 mg/dl 0.82 2.32 enzymatic cholesterol assay 0.0 0 97305 1858
PXO6-2/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 8 13.96 mg/dl 0.76 2.15 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97288 1858
PXO3-2/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 9 1.52 mg/dl 0.16 0.48 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97261 1858
PXO6-1/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 10 0.01 mg/dl 0.0 0.01 enzymatic cholesterol assay 0.0 0 97344 1858
WKY plasma total cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood cholesterol amount male 0 days 7 61.39 mg/dl 4.25 11.24 enzymatic cholesterol assay 0.0 0 98902 2178
WKY plasma very low density lipoprotein cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood VLDL cholesterol amount male 0 days 7 8.11 mg/dl 0.77 2.04 enzymatic cholesterol assay 0.0 0 98907 2178
HTG plasma very low density lipoprotein cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood VLDL cholesterol amount male 0 days 7 11.58 mg/dl 1.54 4.09 enzymatic cholesterol assay 0.0 0 98909 2178
HTG plasma high density lipoprotein cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood HDL cholesterol amount male 0 days 7 31.27 mg/dl 2.32 6.13 enzymatic cholesterol assay 0.0 0 98916 2178
SD-Lepem1Sage-/- liver cholesterol level control condition (for 126 days) D'souza AM, et al., Endocrinology. 2014 Apr;155(4):1268-79. doi: 10.1210/en.2013-1523. Epub 2014 Jan 27. liver cholesterol amount male 126 days 6 2.16 mg/g 0.12 0.3 enzymatic cholesterol assay 0.0 0 104447 2949
BC/CpbU serum total cholesterol level fasting (for 16 hours) Bonne AC, et al., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9. blood cholesterol amount male 49 days 6 133.2 mg/dl 3.94 9.65 enzymatic cholesterol assay 0 12626 271
LEW/OlaHsd serum total cholesterol level controlled olive oil content diet (5 %) (for 28 days) and controlled cholesterol content diet (2 %) (for 28 days) then fasting (for 16 hours) Bonne AC, et al., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9. blood cholesterol amount female 77 days 6 603.47 mg/dl 96.15 235.52 enzymatic cholesterol assay 0 12643 271
PXO6-3/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 10 56.0 mg/dl 1.6 5.06 enzymatic cholesterol assay 0.0 0 97217 1858
SHR.BN-(D8Mit5-D8Mgh6)/Ipcv blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 13 0.07 mg/dl 0.01 0.04 enzymatic cholesterol assay 0.0 0 97353 1858
PXO2/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 11 0.17 mg/dl 0.03 0.1 enzymatic cholesterol assay 0.0 0 97359 1858
LEW/OlaHsd serum total cholesterol level fasting (for 16 hours) Bonne AC, et al., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9. blood cholesterol amount female 49 days 6 110.81 mg/dl 2.05 5.02 enzymatic cholesterol assay 0 12642 271
PXO6-1/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 10 10.95 mg/dl 0.71 2.25 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97283 1858
PXO6-2/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 8 1.58 mg/dl 0.2 0.57 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97262 1858
PXO8-2/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 13 3.68 mg/dl 0.31 1.12 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97267 1858
PXO5-1/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 11 6.31 mg/dl 0.45 1.49 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97270 1858
PXO1/Cub blood very low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood VLDL cholesterol amount male 127 days 11 7.32 mg/dl 1.11 3.68 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97273 1858
PXO6-1/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 10 42.9 mg/dl 1.7 5.38 enzymatic cholesterol assay 0.0 0 97210 1858
PXO8-1/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 10 12.56 mg/dl 0.61 1.93 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97287 1858
PXO10/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 12 0.12 mg/dl 0.02 0.07 enzymatic cholesterol assay 0.0 0 97355 1858
BXH2/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 18 0.16 mg/dl 0.04 0.17 enzymatic cholesterol assay 0.0 0 97358 1858
HTG plasma low density lipoprotein cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood LDL cholesterol amount male 0 days 7 11.97 mg/dl 1.54 4.09 enzymatic cholesterol assay 0.0 0 98913 2178
WKY plasma high density lipoprotein cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood HDL cholesterol amount male 0 days 7 21.62 mg/dl 1.54 4.09 enzymatic cholesterol assay 0.0 0 98915 2178
BC/CpbU serum total cholesterol level fasting (for 16 hours) Bonne AC, et al., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):2072-9. blood cholesterol amount female 49 days 6 133.59 mg/dl 3.63 8.88 enzymatic cholesterol assay 0 12628 271
BN-Lx/Cub liver cholesterol level control condition Bottger A, et al., Biochem Biophys Res Commun 1998 May 8;246(1):272-5. liver cholesterol amount not specified 77 days 0 3.48 mg/g enzymatic cholesterol assay 0.0 0 cholesterol measurement test umole/g, liver cholesterol measurement 68975 1036
PXO2/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 11 22.72 mg/dl 0.93 3.08 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97296 1858
PXO8-1/Cub blood total cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood cholesterol amount male 127 days 10 62.0 mg/dl 1.3 4.11 enzymatic cholesterol assay 0.0 0 97224 1858
PXO6-3/Cub blood chylomicron cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood chylomicron cholesterol amount male 127 days 10 0.02 mg/dl 0.0 0.01 enzymatic cholesterol assay 0.0 0 97345 1858
PXO10/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 12 22.0 mg/dl 1.47 5.09 enzymatic cholesterol assay 0.0 0 97297 1858
PXO8-1/Cub blood high density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood HDL cholesterol amount male 127 days 10 45.97 mg/dl 1.02 3.23 enzymatic cholesterol assay 0.0 0 97310 1858
PXO8-2/Cub blood low density lipoprotein cholesterol level controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. blood LDL cholesterol amount male 127 days 13 11.95 mg/dl 0.24 0.87 enzymatic cholesterol assay 0.0 0 change to mg/dl when available 97285 1858
WKY liver cholesterol level controlled cholesterol content diet (1 %) (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. liver cholesterol amount male 0 days 7 5.89 mg/g 0.34 0.91 enzymatic cholesterol assay 0.0 0 98895 2178
WKY plasma very low density lipoprotein cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood VLDL cholesterol amount male 0 days 7 2.7 mg/dl 0.39 1.02 enzymatic cholesterol assay 0.0 0 98906 2178
WKY plasma high density lipoprotein cholesterol level standard diet (for 20 days) Orolin J, et al., Food Chem Toxicol. 2009 Oct;47(10):2624-30. doi: 10.1016/j.fct.2009.07.022. Epub 2009 Jul 25. blood HDL cholesterol amount male 0 days 7 28.57 mg/dl 1.16 3.06 enzymatic cholesterol assay 0.0 0 98914 2178