SPRD.WKY-(D18Wox8-D18Rat44)/Ibmm |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
186 days-191 days |
46 |
7.61 |
null |
0.07 |
0.45 |
necropsy |
0 |
DMBA oral gavage |
0 |
|
necropsy |
|
11342 |
73 |
SS.BN-(D6Rat149-D6Arb3)/Mcwi |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
14 |
4.77 |
null |
0.64 |
2.39 |
necropsy |
0 |
DMBA oral gavage |
105 |
days |
necropsy |
|
65571 |
86 |
COP/OlaHsd |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Haag JD, et al., Cancer Res 2003 Sep 15;63(18):5808-12 |
mammary gland integrity trait |
female |
155 days-160 days |
16 |
0.25 |
null |
0.1 |
0.4 |
necropsy |
|
|
0 |
|
|
3X3 mm diameter or larger |
11747 |
143 |
SS.BN-(D6Rat149-D6Arb3)/Mcwi |
ratio of deaths related to DMBA toxicity to total study population during a period of time |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
total life span |
female |
152 days-162 days |
14 |
57.0 |
% |
|
|
necropsy |
0 |
DMBA oral gavage |
105 |
days |
|
ratio of deaths related to DMBA toxicity to total study population during a period of time (CMO:0003809) |
65575 |
86 |
SS.BN-(D13Hmgc64-RN34_13048990782)/Mcwi |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
14 |
4.86 |
null |
0.7 |
2.63 |
necropsy |
0 |
DMBA oral gavage |
105 |
days |
necropsy |
|
65573 |
86 |
SS-Chr 19BN/Mcwi |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
14 |
8.79 |
null |
1.25 |
4.68 |
necropsy |
0 |
DMBA oral gavage |
105 |
days |
necropsy |
|
11507 |
86 |
WF/NHsd |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Haag JD, et al., Cancer Res 2003 Sep 15;63(18):5808-12 |
mammary gland integrity trait |
female |
155 days-160 days |
29 |
6.3 |
null |
0.5 |
2.69 |
necropsy |
0.0 |
|
0 |
|
|
3X3 mm diameter or larger |
70167 |
143 |
SS/JrHsdMcwi |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
40 |
2.45 |
null |
0.21 |
1.32 |
necropsy |
0 |
DMBA oral gavage |
105 |
days |
necropsy |
|
11488 |
86 |
SS-Chr 16BN/Mcwi |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
13 |
6.31 |
null |
1.61 |
5.79 |
necropsy |
0 |
DMBA oral gavage |
105 |
days |
necropsy |
|
11504 |
86 |
WKY/NHsd |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Lan H, et al., Genetics 2001 Jan;157(1):331-9 |
mammary gland integrity trait |
female |
169 days-174 days |
17 |
0.0 |
null |
|
|
necropsy |
|
|
0 |
|
|
3X3 mm diameter or larger |
11741 |
141 |
WF/NHsd |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Lan H, et al., Genetics 2001 Jan;157(1):331-9 |
mammary gland integrity trait |
female |
169 days-174 days |
21 |
7.3 |
null |
0.98 |
4.5 |
necropsy |
|
|
0 |
|
|
3X3 mm diameter or larger |
11742 |
141 |
SS.BN-(D6Rat149-D6Got171)/Mcwi |
ratio of deaths related to DMBA toxicity to total study population during a period of time |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
total life span |
female |
152 days-162 days |
15 |
40.0 |
% |
|
|
necropsy |
0 |
DMBA oral gavage |
105 |
days |
|
ratio of deaths related to DMBA toxicity to total study population during a period of time (CMO:0003809) |
65577 |
86 |
SPRD/Ztm |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
186 days-191 days |
48 |
11.23 |
null |
0.07 |
0.51 |
necropsy |
0 |
DMBA oral gavage |
0 |
|
necropsy |
|
11340 |
73 |
WF.COP-(D2Mit29-D2Rat201)/Uwm |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Haag JD, et al., Cancer Res 2003 Sep 15;63(18):5808-12 |
mammary gland integrity trait |
female |
155 days-160 days |
19 |
1.5 |
null |
0.3 |
1.31 |
necropsy |
0.0 |
|
0 |
|
|
3X3 mm diameter or larger |
70168 |
143 |
SPRD.WKY-(D5Rat190-D5Rat114)/Ibmm |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
186 days-191 days |
14 |
3.93 |
null |
0.17 |
0.64 |
necropsy |
0 |
DMBA oral gavage |
0 |
|
necropsy |
|
11341 |
73 |
SS-Chr 13BN/Mcwi |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
13 |
5.33 |
null |
1.21 |
4.38 |
necropsy |
0 |
DMBA oral gavage |
105 |
days |
necropsy |
|
11501 |
86 |
SS.BN-(D6Rat149-D6Rat18)/Mcwi |
ratio of deaths related to DMBA toxicity to total study population during a period of time |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
total life span |
female |
152 days-162 days |
15 |
80.0 |
% |
|
|
necropsy |
0 |
DMBA oral gavage |
105 |
days |
|
ratio of deaths related to DMBA toxicity to total study population during a period of time (CMO:0003809) |
65576 |
86 |
WF/NHsd |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Haag JD, et al., Cancer Res 2003 Sep 15;63(18):5808-12 |
mammary gland integrity trait |
female |
155 days-160 days |
30 |
8.1 |
null |
0.7 |
3.83 |
necropsy |
|
|
0 |
|
|
3X3 mm diameter or larger |
11746 |
143 |
WF |
mammary tumor number |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (between 126 and 140 days) |
Shepel LA, et al., Genetics 1998 May;149(1):289-99 |
mammary gland integrity trait |
female |
181 days-200 days |
53 |
3.62 |
null |
0.27 |
1.95 |
necropsy |
0.0 |
DMBA oral gavage |
126 |
days |
from 126 to 140 days |
|
66100 |
689 |
SS-Chr 6BN/Mcwi |
ratio of deaths related to DMBA toxicity to total study population during a period of time |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
total life span |
female |
152 days-162 days |
20 |
95.0 |
% |
|
|
necropsy |
0 |
DMBA oral gavage |
105 |
days |
|
ratio of deaths related to DMBA toxicity to total study population during a period of time (CMO:0003809) |
65578 |
86 |