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PhenoMiner Database Result        View data table  |  Download data table  |  View expanded data table        

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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1aCondition 1bCondition 2aCondition 2bCondition 3aCondition 3b
10maximum contractile force per wet weight of aortaFHH-Chr 8BN/Mcwifemale1.226g/mgpotassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)55799potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
10maximum contractile force per wet weight of aortaFHH-Chr 8BN/Mcwimale0.803g/mgpotassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)55811potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
10maximum contractile force per wet weight of aortaFHH-Chr 8BN/Mcwifemale1.058g/mgcontrolled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)57345controlled sodium content diet (4 %) (for 21 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
10maximum contractile force per wet weight of aortaFHH-Chr 8BN/Mcwimale0.947g/mgcontrolled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours)57357controlled sodium content diet (4 %) (for 21 days)potassium ion (80 mmol/l) (for 0.2 hours)phenylephrine (10 umol/l) (for 0.2 hours)
9concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH-Chr 8BN/Mcwifemale1.6192E-7molephenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)55905phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH-Chr 8BN/Mcwimale1.354E-7molephenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)55917phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
10concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH-Chr 8BN/Mcwifemale2.4364E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)56531controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)FHH-Chr 8BN/Mcwimale5.3688E-7molecontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)56543controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwifemale-7.5268phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)55286phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
10logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwimale-7.9051phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)55298phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
9logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwifemale-7.8689controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)56116controlled sodium content diet (4 %) (for 21 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
10logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwimale-8.0684controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)56128controlled sodium content diet (4 %) (for 21 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
10acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselFHH-Chr 8BN/Mcwifemale78.8%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)54791controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselFHH-Chr 8BN/Mcwimale61.7778%controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)54803controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselFHH-Chr 8BN/Mcwifemale75.7778%phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)57235phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vesselFHH-Chr 8BN/Mcwimale76.6667%phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)57247phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwifemale-6.8066phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)55636phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwimale-6.9204phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)55648phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
10logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwifemale-6.8058controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)56926controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)FHH-Chr 8BN/Mcwimale-6.6664controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)56938controlled sodium content diet (4 %) (for 21 days)phenylephrine (1 umol/l) (for 0.2 hours)acetylcholine (0-30 umol/l) drug dose time series (for 1 hours)
9concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH-Chr 8BN/Mcwifemale0.0264umol/lphenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)54685phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
10concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH-Chr 8BN/Mcwimale0.0137umol/lphenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)54697phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
9concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH-Chr 8BN/Mcwifemale0.0193umol/lcontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)54917controlled sodium content diet (4 %) (for 21 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)
10concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)FHH-Chr 8BN/Mcwimale0.0119umol/lcontrolled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours)54929controlled sodium content diet (4 %) (for 21 days)phenylephrine (0-300 umol/l) drug dose time series (for 1.2 hours)

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