F344Elmod3Tn(sbT2/Bart3)2.42Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
2 
7.03 
null 
0.1 
0.15 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62824 
528 
FHHAgtr1bm1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
4 
6.91 
null 
0.04 
0.07 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62825 
528 
FHHCcr2m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
6 
7.08 
null 
0.14 
0.35 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62831 
528 
F344/NHsd 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
8 
6.84 
null 
0.12 
0.34 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62844 
528 
F344Fam19a2Tn(sbT2/Bart3)2.184Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
2 
6.56 
null 
0.14 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62855 
528 
FHHAdipoqm3Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
5 
6.53 
null 
0.15 
0.34 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62860 
528 
FHHAdra1am1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.98 
null 
0.11 
0.32 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62862 
528 
F344AbatTn(sbT2/Bart3)2.163Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
1 
6.65 
null 


Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62863 
528 
FHHTlr4m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
11 
6.85 
null 
0.05 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62869 
528 
F344Stxbp5lTn(sbT2/Bart3)2.202Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
3 
6.67 
null 
0.32 
0.56 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62877 
528 
SSChr 18BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.46 
null 
0.07 
0.22 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
57406 
522 
SS/JrHsdMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
13 
7.13 
null 
0.13 
0.46 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
57410 
522 
SSChr 16BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
3 
6.32 
null 
0.2 
0.35 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Conversion period. Moms had mixed diet, Dyets and Teklad, for 34 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 
55370 
522 
SHR/NCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
7 
7.27 
null 
0.09 
0.24 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Conversion period. Moms had mixed diet, Dyets and Teklad, for 34 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 
55371 
522 
SHR/NCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
7.19 
null 
0.1 
0.3 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Conversion period. Moms had mixed diet, Dyets and Teklad, for 34 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 
55374 
522 
FHHChr 9BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
7 
6.75 
null 
0.04 
0.11 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55683 
522 
SSChr XBN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.79 
null 
0.04 
0.13 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55689 
522 
FHHChr 12BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
11 
7.15 
null 
0.05 
0.16 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55615 
522 
FHHChr 15BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
8 
7.21 
null 
0.09 
0.26 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55617 
522 
FHHChr 10BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
5 
6.61 
null 
0.14 
0.31 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55621 
522 
FHHChr 17BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
6.93 
null 
0.08 
0.23 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55628 
522 
SSChr 15BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
6.77 
null 
0.09 
0.27 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55642 
522 
SSChr 3BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
7 
7.08 
null 
0.08 
0.21 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55643 
522 
FHHChr 19BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
11 
6.69 
null 
0.06 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55645 
522 
SSChr 18BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
8 
7.04 
null 
0.13 
0.36 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55669 
522 
FHHChr 4BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
7.22 
null 
0.07 
0.21 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55670 
522 
SSChr 4BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
14 
6.86 
null 
0.05 
0.19 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55672 
522 
WKY/NCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
8 
7.47 
null 
0.2 
0.56 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
54750 
522 
Hsd:SD 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
19 
7.19 
null 
0.07 
0.3 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 
56226 
522 
SS/JrHsdMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
12 
6.47 
null 
0.05 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Conversion period. Moms had mixed diet, Dyets and Teklad, for 34 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 
56449 
522 
SSChr 18BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.66 
null 
0.08 
0.25 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
55018 
522 
SSChr 18BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.83 
null 
0.06 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
55023 
522 
GH/OmrMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
6.86 
null 
0.04 
0.11 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
55024 
522 
WKY/NCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
15 
7.45 
null 
0.09 
0.33 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
56772 
522 
LEW/Crl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
23 
7.2 
null 
0.06 
0.27 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
56773 
522 
Crl:CD(SD) 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
19 
6.87 
null 
0.07 
0.31 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
56774 
522 
LEW/Crl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
22 
7.09 
null 
0.06 
0.28 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
56778 
522 
FHHChr 9BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
6 
7.19 
null 
0.26 
0.63 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56971 
522 
SS.BN(D8Rat163D8Rat81)/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
7.42 
null 
0.06 
0.17 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56973 
522 
BN/NHsdMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
20 
6.87 
null 
0.08 
0.37 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56976 
522 
FHHChr 15BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
7 
6.99 
null 
0.09 
0.23 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56888 
522 
SSChr 10BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
7 
6.62 
null 
0.12 
0.32 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56890 
522 
SSChr 6BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
15 
6.98 
null 
0.14 
0.56 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56897 
522 
FHHChr 6BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
8 
6.96 
null 
0.05 
0.15 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56900 
522 
FHHChr 15BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
7.07 
null 
0.07 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56907 
522 
SSChr 17BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
8 
7.07 
null 
0.11 
0.31 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56916 
522 
FHHChr 17BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.86 
null 
0.06 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56918 
522 
SSChr 7BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
12 
6.89 
null 
0.08 
0.27 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56920 
522 
FHHChr 3BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.78 
null 
0.07 
0.22 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56931 
522 
FHHChr 13BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
6.95 
null 
0.06 
0.19 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56941 
522 
FHHChr 4BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
7.01 
null 
0.14 
0.42 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56959 
522 
SSChr 19BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
5 
6.72 
null 
0.03 
0.07 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56965 
522 
FHHChr 3BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.49 
null 
0.1 
0.31 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56950 
522 
SS/JrHsdMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
79 
6.98 
null 
0.06 
0.49 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56955 
522 
SS.BN(D8Rat163D8Rat81)/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
7 
7.49 
null 
0.07 
0.17 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56964 
522 
SSChr 9BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.57 
null 
0.05 
0.16 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55608 
522 
SSChr 6BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.84 
null 
0.05 
0.14 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55614 
522 
FHHChr 2BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.89 
null 
0.07 
0.19 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55619 
522 
FHHChr 10BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.54 
null 
0.07 
0.19 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55633 
522 
FHHChr 16BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.84 
null 
0.07 
0.22 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55635 
522 
SSChr 11BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
6.92 
null 
0.09 
0.26 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55657 
522 
FHHChr 1BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
7 
6.9 
null 
0.07 
0.17 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55668 
522 
SS/JrHsdMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.87 
null 
0.06 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55673 
522 
SSGhsrm3Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
1 
6.59 
null 


Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62878 
528 
LE/BluGill 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
14 
7.41 
null 
0.09 
0.33 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
54748 
522 
LE/BluGill 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
14 
7.47 
null 
0.05 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
56777 
522 
F344/DuCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.79 
null 
0.1 
0.33 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
56780 
522 
FHHProcm1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
7 
6.98 
null 
0.12 
0.31 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62833 
528 
FHHHtr1am1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
11 
6.92 
null 
0.07 
0.24 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62834 
528 
F344/NHsd 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
7 
6.61 
null 
0.18 
0.49 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62835 
528 
FHHF10m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
7 
6.8 
null 
0.08 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62846 
528 
FHHTgfbr2m2Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.96 
null 
0.11 
0.33 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62814 
528 
F344Trpc4Tn(sbT2/Bart3)2.192Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
1 
6.97 
null 


Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62815 
528 
FHHSlc8a2m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
15 
7.09 
null 
0.11 
0.41 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62868 
528 
SSSod3m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
12 
6.74 
null 
0.09 
0.3 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62887 
528 
SSChr 18BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.46 
null 
0.08 
0.26 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
57401 
522 
GH/OmrMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
7.1 
null 
0.16 
0.47 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
57412 
522 
BN/NHsdMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
18 
6.94 
null 
0.06 
0.26 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55688 
522 
FHHChr 9BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
4 
6.8 
null 
0.04 
0.08 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55691 
522 
FHHChr 12BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
11 
6.77 
null 
0.11 
0.38 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55599 
522 
SS.BN(D12Arb13D12Rat79)/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
14 
6.94 
null 
0.1 
0.37 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55601 
522 
FHHChr 5BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
7.17 
null 
0.1 
0.31 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55604 
522 
FHHChr XBN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
7.0 
null 
0.06 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55631 
522 
SSChr 5BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.78 
null 
0.1 
0.27 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55632 
522 
FHHChr 8BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
6.92 
null 
0.07 
0.22 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55648 
522 
FHH/EurMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
47 
6.87 
null 
0.04 
0.26 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55658 
522 
SSChr XBN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
6 
6.68 
null 
0.09 
0.23 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55667 
522 
FHHChr 11BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
7 
7.22 
null 
0.06 
0.15 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55674 
522 
LEW/Crl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
24 
7.17 
null 
0.06 
0.32 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
54744 
522 
SS/JrHsdMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
12 
6.94 
null 
0.1 
0.36 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
55019 
522 
SSChr 9BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.88 
null 
0.09 
0.29 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56898 
522 
FHHChr 5BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
7.24 
null 
0.06 
0.17 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56901 
522 
SSChr 6BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
17 
6.61 
null 
0.13 
0.54 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56904 
522 
FHHChr 12BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
16 
6.99 
null 
0.11 
0.44 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56905 
522 
SSChr 10BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
7 
6.41 
null 
0.07 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56906 
522 
SSChr 7BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
7.04 
null 
0.06 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56913 
522 
FHHChr XBN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.96 
null 
0.13 
0.42 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56924 
522 
FHHChr 16BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.89 
null 
0.07 
0.21 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56925 
522 
FHHChr 8BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.81 
null 
0.12 
0.38 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56926 
522 
FHHChr 19BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.89 
null 
0.06 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56928 
522 
SSChr 3BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.98 
null 
0.08 
0.26 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56933 
522 
SSChr 13BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
14 
7.03 
null 
0.11 
0.42 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56940 
522 
SSChr YBN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
18 
6.98 
null 
0.04 
0.19 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56952 
522 
SSChr 18BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
20 
7.08 
null 
0.04 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56954 
522 
SSChr 4BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.61 
null 
0.03 
0.08 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56960 
522 
FHHChr 7BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.96 
null 
0.07 
0.22 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56970 
522 
F344/DuCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
7.14 
null 
0.06 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
56775 
522 
LE/BluGill 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
11 
7.36 
null 
0.02 
0.06 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
56781 
522 
FHHChr 9BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.92 
null 
0.12 
0.35 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56979 
522 
SSChr 10BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
7.03 
null 
0.07 
0.22 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55616 
522 
FHHChr 16BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.72 
null 
0.05 
0.16 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55622 
522 
FHHChr 19BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.74 
null 
0.05 
0.16 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55638 
522 
FHHChr 11BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
7.19 
null 
0.08 
0.25 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55679 
522 
FHHChr 20BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
10 
6.88 
null 
0.06 
0.19 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56942 
522 
SSChr 11BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
6.81 
null 
0.05 
0.14 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56947 
522 
SSChr 11BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.84 
null 
0.04 
0.11 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56953 
522 
SSChr XBN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
6.79 
null 
0.07 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56977 
522 
F344Plcb3Tn(sbT2/Bart3)2.69Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
2 
7.02 
null 
0.12 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62856 
528 
FHH/EurMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
112 
7.0 
null 
0.03 
0.34 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62861 
528 
F344Stxbp5lTn(sbT2/Bart3)2.202Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
1 
7.28 
null 


Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62867 
528 
F344Nrg1Tn(sbT2/Bart3)2.183Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
5 
6.78 
null 
0.08 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62873 
528 
Hsd:SD 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
14 
6.98 
null 
0.11 
0.4 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 
57194 
522 
SHR/NCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
7.62 
null 
0.23 
0.72 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
55022 
522 
FHHAdipoqm2Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
7.16 
null 
0.1 
0.28 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62830 
528 
FHHF10m2Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
17 
6.9 
null 
0.07 
0.3 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62836 
528 
F344Brinp3Tn(sbT2/Bart3)2.189Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
1 
6.92 
null 


Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62837 
528 
FHHNr4a1m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
4 
6.9 
null 
0.18 
0.36 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62839 
528 
FHHHtr1am1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
18 
6.72 
null 
0.07 
0.31 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62842 
528 
F344DccTn(sbT2/Bart3)2.205Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
5 
6.54 
null 
0.08 
0.18 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62848 
528 
FHHTgfbr2m2Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
6.84 
null 
0.1 
0.3 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62819 
528 
F344Trpc4Tn(sbT2/Bart3)2.192Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
2 
6.96 
null 
0.03 
0.05 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62821 
528 
FHHSlc8a2m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
13 
6.94 
null 
0.1 
0.37 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62823 
528 
FHHNr0b2m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
4 
7.04 
null 
0.15 
0.3 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62826 
528 
BNLcatm3Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
3 
6.45 
null 
0.12 
0.21 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62854 
528 
FHHTlr4m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
12 
6.92 
null 
0.07 
0.25 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62865 
528 
FHHEgln3m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
13 
6.85 
null 
0.03 
0.12 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62871 
528 
F344Inpp4bTn(sbT2/Bart3)2.143Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
6 
7.86 
null 
0.7 
1.72 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62872 
528 
SSKlf4m3Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
6.67 
null 
0.08 
0.25 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62882 
528 
SSCpt2m1Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
1 
5.74 
null 


Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 

62884 
528 
SSChr 14BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
6 
7.04 
null 
0.12 
0.3 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55605 
522 
FHHChr 14BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
7.25 
null 
0.1 
0.3 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55618 
522 
SSChr 7BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
7.06 
null 
0.05 
0.14 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55623 
522 
SSChr 17BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
7.1 
null 
0.05 
0.16 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55626 
522 
GH/OmrMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
4 
6.75 
null 
0.06 
0.12 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55629 
522 
FHHChr 13BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
6.91 
null 
0.04 
0.13 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55651 
522 
FHHChr 18BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
6.92 
null 
0.04 
0.13 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55656 
522 
SSChr 13BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
9 
6.57 
null 
0.08 
0.24 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55659 
522 
SSChr 18BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
7.02 
null 
0.09 
0.24 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55664 
522 
SSChr 12BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
8 
6.87 
null 
0.07 
0.21 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55678 
522 
SSChr 4BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
14 
6.88 
null 
0.14 
0.54 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
55680 
522 
WKY/NCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
12 
7.4 
null 
0.12 
0.4 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
54743 
522 
F344/DuCrl 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
13 
6.81 
null 
0.07 
0.24 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 
54746 
522 
SS/JrHsdMcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
7 
6.65 
null 
0.06 
0.17 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Conversion period. Moms had mixed diet, Dyets and Teklad, for 34 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 
56451 
522 
SSChr 16BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
9 
7.74 
null 
0.09 
0.27 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Dyets 
55021 
522 
SSChr 12BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.81 
null 
0.06 
0.2 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56974 
522 
FHHChr 12BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
12 
6.85 
null 
0.07 
0.23 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56889 
522 
SS.BN(D12Arb13D12Rat79)/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
male 
70 days84 days 
12 
7.15 
null 
0.08 
0.29 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56891 
522 
FHHChr 14BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
10 
6.83 
null 
0.09 
0.27 
Download Values

wire myography using a DigiMed tissue force analysis system with force transducer 

0 
Moms and pups used in studies were fed Teklad 
56892 
522 
SSChr 14BN/Mcwi 
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) 
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (030 umol/l) and drug dose time series (for 1 hours) 
PhysGen Vascular data 
vasodilation trait 
female 
70 days84 days 
8 
6.76 
null 
0.08 
0.22 
Download Values

