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Strain |
Phenotype |
Conditions |
Study |
Experiment Name |
Sex |
Age |
# of Animals |
Value |
Units |
SEM |
SD |
Method |
Method Duration |
Post Insult Time Value |
Clinical Measurement Notes |
Record ID |
Study ID |
SHRSP/A3NCrl |
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
control condition |
Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. |
vasodilation trait |
male |
141 days-148 days |
14 |
119.0 |
nmol/l |
15.0 |
56.12 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
percent reversal of contractile response to 0.3uM phenylephrine |
107299 |
3073 |
SHRSP/A3NCrl |
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium chloride content drinking water (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) |
Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. |
vasodilation trait |
male |
141 days-148 days |
8 |
260.0 |
nmol/l |
74.0 |
209.3 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
percent reversal of contractile response to 0.3uM phenylephrine |
107300 |
3073 |
SHRSP/A3NCrl |
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium chloride content drinking water (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) then controlled BAY60-4552 content diet (0.3 mg/kg/d) (for 49 days) |
Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. |
vasodilation trait |
male |
141 days-148 days |
4 |
407.0 |
nmol/l |
158.0 |
316.0 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
percent reversal of contractile response to 0.3uM phenylephrine |
107304 |
3073 |
SHRSP/A3NCrl |
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium chloride content drinking water (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) then controlled GSK2181236A content diet (1 mg/kg/d) (for 49 days) |
Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. |
vasodilation trait |
male |
141 days-148 days |
9 |
328.0 |
nmol/l |
41.0 |
123.0 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
percent reversal of contractile response to 0.3uM phenylephrine |
107303 |
3073 |
SHRSP/A3NCrl |
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium chloride content drinking water (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) then controlled GSK2181236A content diet (0.1 mg/kg/d) (for 49 days) |
Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. |
vasodilation trait |
male |
141 days-148 days |
6 |
460.0 |
nmol/l |
83.0 |
203.31 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
percent reversal of contractile response to 0.3uM phenylephrine |
107302 |
3073 |
SHRSP/A3NCrl |
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium chloride content drinking water (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) then controlled BAY60-4552 content diet (3 mg/kg/d) (for 49 days) |
Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. |
vasodilation trait |
male |
141 days-148 days |
9 |
385.0 |
nmol/l |
89.0 |
267.0 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
percent reversal of contractile response to 0.3uM phenylephrine |
107305 |
3073 |
|