SS/JrHsdMcwi |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
40 |
|
79.8 |
d |
0.59 |
3.71 |
manual palpation method |
|
0 |
DMBA oral gavage |
105 |
days |
200ng DMBA/10 ml seasme oil |
|
65568 |
86 |
ACI/SegHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (between 147 and 195 days) |
Shull JD, et al., Endocrinology 2001 Dec;142(12):5124-30 |
mammary gland integrity trait |
female |
206 days-264 days |
31 |
|
141.0 |
d |
4.85 |
27.0 |
manual palpation method |
|
|
|
0 |
|
|
mean |
11748 |
144 |
ACI/SegHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (between 193 and 199 days) |
Schaffer BS, et al., Cancer Res. 2006 Aug 1;66(15):7793-800 |
mammary gland integrity trait |
female |
143 days-259 days |
22 |
|
136.0 |
d |
6.0 |
28.14 |
manual palpation method |
|
0.0 |
crystalline implant |
0 |
|
|
|
11383 |
81 |
ACI/SegHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (between 193 and 199 days) |
Schaffer BS, et al., Cancer Res. 2006 Aug 1;66(15):7793-800 |
mammary gland integrity trait |
female |
143 days-259 days |
22 |
median |
133.0 |
d |
|
|
manual palpation method |
|
0 |
crystalline implant |
0 |
|
|
|
65763 |
81 |
SS.BN-(D13Hmgc64-RN34_13048990782)/Mcwi |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
14 |
|
48.51 |
d |
12.07 |
45.15 |
manual palpation method |
|
0 |
DMBA oral gavage |
105 |
days |
200ng DMBA/10 ml seasme oil |
|
65572 |
86 |
ACI.COP-(D6Rat80-D6Rat146)/Shul |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (for 196 days) |
Kurz SG, et al., Endocrinology. 2008 Apr 17 |
mammary gland integrity trait |
female |
0 days-259 days |
17 |
|
165.0 |
d |
|
|
manual palpation method |
|
0 |
|
0 |
|
|
median |
11371 |
75 |
COP/OlaHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (between 212 and 330 days) |
Shull JD, et al., Endocrinology 2001 Dec;142(12):5124-30 |
mammary gland integrity trait |
female |
212 days-330 days |
7 |
|
208.0 |
d |
7.56 |
20.0 |
manual palpation method |
|
|
|
0 |
|
|
mean |
11749 |
144 |
ACI/SegHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (between 147 and 195 days) |
Shull JD, et al., Endocrinology 2001 Dec;142(12):5124-30 |
mammary gland integrity trait |
female |
206 days-264 days |
31 |
median |
140.0 |
d |
|
|
manual palpation method |
|
|
|
0 |
|
|
median |
11750 |
144 |
COP/OlaHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (between 212 and 330 days) |
Shull JD, et al., Endocrinology 2001 Dec;142(12):5124-30 |
mammary gland integrity trait |
female |
212 days-330 days |
7 |
median |
195.0 |
d |
|
|
manual palpation method |
|
|
|
0 |
|
|
median |
11751 |
144 |
Crl:CD(SD) |
post-insult time to mammary tumor formation |
maternal milk (for 20 days) and bisphenol A (25 ug/kg) (for 15 days) then 7,12-dimethyltetraphene (DMBA) (30 mg/kg) (for 1 days) |
Jenkins S, et al., Environ Health Perspect. 2009 Jun;117(6):910-5. doi: 10.1289/ehp.11751. Epub 2009 Jan 7. |
mammary gland integrity trait |
female |
0 days-365 days |
34 |
median |
53.0 |
d |
|
|
manual palpation method |
|
0.0 |
|
0 |
|
|
|
76268 |
1558 |
SS-Chr 3BN/Mcwi |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
14 |
|
95.48 |
d |
1.67 |
6.23 |
manual palpation method |
|
0 |
DMBA oral gavage |
105 |
days |
200 mg DMBA in 10 ml seame oil |
|
11491 |
86 |
Crl:CD(SD) |
post-insult time to mammary tumor formation |
maternal milk (for 20 days) and vehicle control condition (for 15 days) then 7,12-dimethyltetraphene (DMBA) (30 mg/kg) (for 1 days) |
Jenkins S, et al., Environ Health Perspect. 2009 Jun;117(6):910-5. doi: 10.1289/ehp.11751. Epub 2009 Jan 7. |
mammary gland integrity trait |
female |
0 days-365 days |
32 |
median |
65.0 |
d |
|
|
manual palpation method |
|
0.0 |
|
0 |
|
|
|
76267 |
1558 |
ACI/SegHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (between 99 and 197 days) |
Shull JD, et al., Carcinogenesis. 1997 Aug;18(8):1595-601 |
mammary gland integrity trait |
female |
160 days-260 days |
21 |
median |
143.0 |
d |
|
|
manual palpation method |
mammary gland |
0.0 |
|
0 |
|
|
|
66111 |
76 |
SPRD.WKY-(D18Wox8-D18Rat44)/Ibmm |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
99 days-104 days |
46 |
|
45.91 |
d |
0.19 |
1.27 |
manual palpation method |
|
0 |
DMBA oral gavage |
0 |
|
|
|
11345 |
73 |
SS-Chr 14BN/Mcwi |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
14 |
|
46.69 |
d |
1.09 |
4.06 |
manual palpation method |
|
0 |
DMBA oral gavage |
105 |
days |
200 mg DMBA in 10 ml seame oil |
|
65570 |
86 |
SS.BN-(D6Rat149-D6Arb3)/Mcwi |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
14 |
|
52.37 |
d |
1.32 |
4.94 |
manual palpation method |
|
0 |
DMBA oral gavage |
105 |
days |
200ng DMBA/10 ml seasme oil |
|
65574 |
86 |
ACI/SegHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (between 99 and 197 days) |
Shull JD, et al., Carcinogenesis. 1997 Aug;18(8):1595-601 |
mammary gland integrity trait |
female |
160 days-260 days |
21 |
serial mean |
145.0 |
d |
|
|
manual palpation method |
mammary gland |
0.0 |
|
0 |
|
|
|
66104 |
76 |
SS-Chr 19BN/Mcwi |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
14 |
|
44.03 |
d |
0.41 |
1.54 |
manual palpation method |
|
0 |
DMBA oral gavage |
105 |
days |
200 mg DMBA in 10 ml seame oil |
|
65569 |
86 |
ACI/SegHsd |
post-insult time to mammary tumor formation |
17 beta-estradiol (27.5 mg) (for 196 days) |
Kurz SG, et al., Endocrinology. 2008 Apr 17 |
mammary gland integrity trait |
female |
0 days-259 days |
21 |
|
145.0 |
d |
|
|
manual palpation method |
|
0 |
|
0 |
|
|
median |
11375 |
75 |
Crl:CD(SD) |
post-insult time to mammary tumor formation |
maternal milk (for 20 days) and bisphenol A (250 ug/kg) (for 15 days) then 7,12-dimethyltetraphene (DMBA) (30 mg/kg) (for 1 days) |
Jenkins S, et al., Environ Health Perspect. 2009 Jun;117(6):910-5. doi: 10.1289/ehp.11751. Epub 2009 Jan 7. |
mammary gland integrity trait |
female |
0 days-365 days |
24 |
median |
56.5 |
d |
|
|
manual palpation method |
|
0.0 |
|
0 |
|
|
|
76269 |
1558 |
SPRD/Ztm |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
97 days-102 days |
48 |
|
43.8 |
d |
0.13 |
0.9 |
manual palpation method |
|
0 |
DMBA oral gavage |
0 |
|
|
|
11343 |
73 |
SPRD.WKY-(D5Rat190-D5Rat114)/Ibmm |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
107 days-112 days |
14 |
|
53.4 |
d |
0.64 |
2.4 |
manual palpation method |
|
0 |
DMBA oral gavage |
0 |
|
|
|
11344 |
73 |
SS-Chr 9BN/Mcwi |
post-insult time to mammary tumor formation |
7,12-dimethyltetraphene (DMBA) (65 mg/kg) (for 105 days) |
Adamovic T, et al., Genes Chromosomes Cancer. 2010 Nov;49(11):1035-45 |
mammary gland integrity trait |
female |
152 days-162 days |
40 |
|
58.31 |
d |
0.85 |
5.39 |
manual palpation method |
|
0 |
DMBA oral gavage |
105 |
days |
200 mg DMBA in 10 ml seame oil |
|
65567 |
86 |