SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
13 |
|
9.69 |
IU/g |
1.44 |
5.18 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
49829 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
14 |
|
0.29 |
IU/g |
0.07 |
0.25 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47487 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
13 |
|
11.23 |
ml/min/g |
0.85 |
3.05 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46670 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
6 |
|
10.17 |
IU/g |
0.68 |
1.66 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
45113 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
15 |
|
0.43 |
IU/g |
0.07 |
0.28 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47346 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
9 |
|
0.31 |
IU/g |
0.06 |
0.19 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47482 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
15 |
|
9.0 |
ml/min/g |
0.57 |
2.21 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46887 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
|
10.89 |
ml/min/g |
0.5 |
1.49 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46667 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
6 |
|
5.29 |
ml/min/g |
0.49 |
1.2 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
44898 |
461 |
SS-Chr 18BN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
14 |
post-ischemic value/pre-ischemic value x 100% |
57.19 |
% |
4.21 |
15.74 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47094 |
461 |
SS-Chr 18BN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
54.01 |
% |
4.26 |
12.77 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47091 |
461 |
SS-Chr 18BN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
39.86 |
% |
9.5 |
26.86 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
47169 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
5 |
|
8.02 |
IU/g |
1.87 |
4.19 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
45116 |
461 |
SS-Chr 18BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
15 |
post-ischemic value/pre-ischemic value x 100% |
80.0 |
% |
2.9 |
11.23 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46080 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
14 |
|
0.4 |
IU/g |
0.07 |
0.25 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
47351 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
7 |
|
5.28 |
ml/min/g |
0.35 |
0.92 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
44901 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
8 |
|
0.2 |
IU/g |
0.03 |
0.08 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50089 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
15 |
|
10.44 |
IU/g |
1.18 |
4.56 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
49835 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
8 |
|
0.19 |
IU/g |
0.03 |
0.09 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
50092 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
5 |
|
9.03 |
IU/g |
1.64 |
3.67 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
45700 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
15 |
|
8.15 |
ml/min/g |
0.71 |
2.73 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46218 |
461 |
SS-Chr 18BN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
56.79 |
% |
10.41 |
29.44 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
47172 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
15 |
|
9.52 |
ml/min/g |
0.63 |
2.44 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46884 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
|
5.9 |
ml/min/g |
0.57 |
1.7 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44732 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
8 |
|
10.03 |
ml/min/g |
0.24 |
0.68 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
46633 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
7 |
|
8.16 |
ml/min/g |
0.54 |
1.42 |
isolated perfused heart effluent collection |
|
0 |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
46636 |
461 |
SS-Chr 18BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
15 |
post-ischemic value/pre-ischemic value x 100% |
91.14 |
% |
5.53 |
21.42 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46083 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
15 |
|
7.61 |
ml/min/g |
0.57 |
2.19 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
46215 |
461 |
SS-Chr 18BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
5 |
|
6.93 |
IU/g |
2.76 |
6.17 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
45693 |
461 |
SS-Chr 18BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
14 |
|
7.4 |
ml/min/g |
1.07 |
3.99 |
isolated perfused heart effluent collection |
|
0 |
Moms and pups used in studies were fed Teklad |
44735 |
461 |