GK |
blood glucose level area under curve (AUC) |
resting (for 42 days) then fasting (for 12 hours) then glucose (1 g/kg) (for 2 hours) |
Kupai K, et al., Diabetol Metab Syndr. 2015 Oct 6;7:85. doi: 10.1186/s13098-015-0080-x. eCollection 2015. |
blood glucose amount |
male |
0 days
| 20 |
38075.27 |
(mg/dl) x min |
978.55 |
4376.19 |
oral glucose tolerance test |
0.0 |
oral glucose |
120 |
min |
109907 |
3160 |
GK |
plasma glucose level |
fasting (for 16 hours) then glucose (2 g/kg) (between 0.5 and 3 hours) |
Weng S, etal., Obes Surg. 2017 Mar;27(3):657-664. doi: 10.1007/s11695-016-2320-z. |
blood glucose amount |
male |
77 days
| 10 |
6.84 |
mg/dl |
0.13 |
0.42 |
oral glucose tolerance test |
0.0 |
|
0 |
|
109090 |
3111 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 1 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 9 |
273.6 |
mg/dl |
14.4 |
43.2 |
oral glucose tolerance test |
0.0 |
oral glucose |
60 |
min |
110752 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 0.5 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 9 |
289.8 |
mg/dl |
12.6 |
37.8 |
oral glucose tolerance test |
0.0 |
oral glucose |
30 |
min |
110749 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 2 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 8 |
217.8 |
mg/dl |
10.8 |
30.55 |
oral glucose tolerance test |
0.0 |
oral glucose |
120 |
min |
110756 |
3183 |
GK |
blood glucose level |
resting (for 42 days) then fasting (for 12 hours) then glucose (1 g/kg) (for 2 hours) |
Kupai K, et al., Diabetol Metab Syndr. 2015 Oct 6;7:85. doi: 10.1186/s13098-015-0080-x. eCollection 2015. |
blood glucose amount |
male |
0 days
| 20 |
352.98 |
mg/dl |
13.68 |
61.18 |
oral glucose tolerance test |
0.0 |
oral glucose |
120 |
min |
109905 |
3160 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 0.5 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 8 |
250.2 |
mg/dl |
21.6 |
61.09 |
oral glucose tolerance test |
0.0 |
oral glucose |
30 |
min |
110747 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 10 |
124.2 |
mg/dl |
7.2 |
22.77 |
oral glucose tolerance test |
0.0 |
oral glucose |
0 |
min |
110745 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 1 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 8 |
262.8 |
mg/dl |
23.4 |
66.19 |
oral glucose tolerance test |
0.0 |
oral glucose |
60 |
min |
110750 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 2 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 9 |
219.6 |
mg/dl |
7.2 |
21.6 |
oral glucose tolerance test |
0.0 |
oral glucose |
120 |
min |
110758 |
3183 |
GK |
blood glucose level |
fasting (for 16 hours) then glucose (2 g/kg) (for 2 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
blood glucose amount |
male |
134 days
| 6 |
301.0 |
mg/dl |
23.0 |
56.34 |
oral glucose tolerance test |
0.0 |
|
0 |
|
103516 |
2827 |
WKY/NCrl |
blood glucose level |
fasting (for 16 hours) then glucose (2 g/kg) (for 2 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
blood glucose amount |
male |
134 days
| 6 |
118.0 |
mg/dl |
4.0 |
9.8 |
oral glucose tolerance test |
0.0 |
|
0 |
|
103515 |
2827 |
GK |
blood glucose level |
salidroside (40 mg/kg) (for 28 days) then fasting (for 16 hours) then glucose (2 g/kg) (for 2 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
blood glucose amount |
male |
168 days
| 6 |
297.0 |
mg/dl |
25.0 |
61.24 |
oral glucose tolerance test |
0.0 |
|
0 |
|
103521 |
2827 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 9 |
113.4 |
mg/dl |
5.4 |
16.2 |
oral glucose tolerance test |
0.0 |
oral glucose |
0 |
min |
110746 |
3183 |
GK |
plasma glucose level |
fasting (for 16 hours) then glucose (2 g/kg) (between 0.5 and 3 hours) |
Weng S, etal., Obes Surg. 2017 Mar;27(3):657-664. doi: 10.1007/s11695-016-2320-z. |
blood glucose amount |
male |
77 days
| 10 |
6.83 |
mg/dl |
0.13 |
0.41 |
oral glucose tolerance test |
0.0 |
|
0 |
|
109089 |
3111 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 1.5 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 10 |
279.0 |
mg/dl |
14.4 |
45.54 |
oral glucose tolerance test |
0.0 |
oral glucose |
90 |
min |
110754 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 1.5 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 9 |
244.8 |
mg/dl |
12.6 |
37.8 |
oral glucose tolerance test |
0.0 |
oral glucose |
90 |
min |
110755 |
3183 |
GK |
blood glucose level |
fasting (for 16 hours) then glucose (2 g/kg) (for 2 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
blood glucose amount |
male |
134 days
| 6 |
331.0 |
mg/dl |
30.0 |
73.48 |
oral glucose tolerance test |
0.0 |
|
0 |
|
103517 |
2827 |
GK |
blood glucose level |
vehicle control condition (for 28 days) then fasting (for 16 hours) then glucose (2 g/kg) (for 2 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
blood glucose amount |
male |
168 days
| 6 |
278.0 |
mg/dl |
20.0 |
48.99 |
oral glucose tolerance test |
0.0 |
|
0 |
|
103520 |
2827 |
WKY/NCrl |
blood glucose level |
salidroside (40 mg/kg) (for 28 days) then fasting (for 16 hours) then glucose (2 g/kg) (for 2 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
blood glucose amount |
male |
168 days
| 6 |
121.0 |
mg/dl |
2.0 |
4.9 |
oral glucose tolerance test |
0.0 |
|
0 |
|
103519 |
2827 |
GK |
blood glucose level |
running (3.91 km/d) (for 42 days) then fasting (for 12 hours) then glucose (1 g/kg) (for 2 hours) |
Kupai K, et al., Diabetol Metab Syndr. 2015 Oct 6;7:85. doi: 10.1186/s13098-015-0080-x. eCollection 2015. |
blood glucose amount |
male |
0 days
| 20 |
262.44 |
mg/dl |
15.84 |
70.84 |
oral glucose tolerance test |
0.0 |
oral glucose |
120 |
min |
109906 |
3160 |
Crlj:WI |
blood glucose level area under curve (AUC) |
fasting (for 16 hours) then glucose (2 g/kg) (for 3 hours) |
Ohta T, et al., Br J Pharmacol. 1999 Apr;126(7):1674-80. doi: 10.1038/sj.bjp.0702481. |
blood glucose amount |
male |
56 days
| 5 |
13284.0 |
(mg/dl) x min |
1404.0 |
3139.44 |
oral glucose tolerance test |
0.0 |
|
0 |
|
110772 |
3185 |
GK |
plasma glucose level |
fasting (for 16 hours) then glucose (2 g/kg) (between 0.5 and 3 hours) |
Weng S, etal., Obes Surg. 2017 Mar;27(3):657-664. doi: 10.1007/s11695-016-2320-z. |
blood glucose amount |
male |
77 days
| 10 |
6.74 |
mg/dl |
0.27 |
0.84 |
oral glucose tolerance test |
0.0 |
|
0 |
|
109091 |
3111 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 0.5 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 10 |
289.8 |
mg/dl |
21.6 |
68.31 |
oral glucose tolerance test |
0.0 |
oral glucose |
30 |
min |
110748 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 1 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 10 |
307.8 |
mg/dl |
19.8 |
62.61 |
oral glucose tolerance test |
0.0 |
oral glucose |
60 |
min |
110751 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 1.5 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 8 |
253.8 |
mg/dl |
16.2 |
45.82 |
oral glucose tolerance test |
0.0 |
oral glucose |
90 |
min |
110753 |
3183 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose (for 2 hours) |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 10 |
234.0 |
mg/dl |
9.0 |
28.46 |
oral glucose tolerance test |
0.0 |
oral glucose |
120 |
min |
110757 |
3183 |
WKY/NCrl |
blood glucose level |
fasting (for 16 hours) then glucose (2 g/kg) (for 2 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
blood glucose amount |
male |
134 days
| 6 |
124.0 |
mg/dl |
3.0 |
7.35 |
oral glucose tolerance test |
0.0 |
|
0 |
|
103514 |
2827 |
WKY/NCrl |
blood glucose level |
vehicle control condition (for 28 days) then fasting (for 16 hours) then glucose (2 g/kg) (for 2 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
blood glucose amount |
male |
168 days
| 6 |
125.0 |
mg/dl |
3.0 |
7.35 |
oral glucose tolerance test |
0.0 |
|
0 |
|
103518 |
2827 |
GK |
blood glucose level |
resting (for 42 days) then fasting (for 12 hours) then glucose (1 g/kg) (for 1 hours) |
Kupai K, et al., Diabetol Metab Syndr. 2015 Oct 6;7:85. doi: 10.1186/s13098-015-0080-x. eCollection 2015. |
blood glucose amount |
male |
0 days
| 20 |
369.18 |
mg/dl |
10.44 |
46.69 |
oral glucose tolerance test |
0.0 |
oral glucose |
60 |
min |
109903 |
3160 |
GK |
blood glucose level |
running (3.91 km/d) (for 42 days) then fasting (for 12 hours) then glucose (1 g/kg) (for 1 hours) |
Kupai K, et al., Diabetol Metab Syndr. 2015 Oct 6;7:85. doi: 10.1186/s13098-015-0080-x. eCollection 2015. |
blood glucose amount |
male |
0 days
| 20 |
295.02 |
mg/dl |
14.58 |
65.2 |
oral glucose tolerance test |
0.0 |
oral glucose |
60 |
min |
109904 |
3160 |
GK |
blood glucose level area under curve (AUC) |
running (3.91 km/d) (for 42 days) then fasting (for 12 hours) then glucose (1 g/kg) (for 2 hours) |
Kupai K, et al., Diabetol Metab Syndr. 2015 Oct 6;7:85. doi: 10.1186/s13098-015-0080-x. eCollection 2015. |
blood glucose amount |
male |
0 days
| 20 |
29553.82 |
(mg/dl) x min |
1274.73 |
5700.75 |
oral glucose tolerance test |
0.0 |
oral glucose |
120 |
min |
109908 |
3160 |
GK/CskCrlj |
blood glucose level area under curve (AUC) |
fasting (for 16 hours) then glucose (2 g/kg) (for 3 hours) |
Ohta T, et al., Br J Pharmacol. 1999 Apr;126(7):1674-80. doi: 10.1038/sj.bjp.0702481. |
blood glucose amount |
male |
56 days
| 5 |
22896.0 |
(mg/dl) x min |
1404.0 |
3139.44 |
oral glucose tolerance test |
0.0 |
|
0 |
|
110773 |
3185 |
GK/MolTac |
blood glucose level |
fasting (between 14 and 18 hours) then glucose |
Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22. |
blood glucose amount |
male |
105 days
| 8 |
120.6 |
mg/dl |
3.6 |
10.18 |
oral glucose tolerance test |
0.0 |
oral glucose |
0 |
min |
110744 |
3183 |