Phenominer Database Results (68 results)

 

Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled NG-nitroarginine methyl ester content in acidified drinking water (8-13 mg/kg/d) (for 126 days) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 8 6.0 % 2.0 5.66 ex vivo light microscopy with histochemistry 0.0 0 67953 751
ACI.FHH-(D17Rat117-D17Arb5)(D17Rat180-D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then controlled NG-nitroarginine methyl ester content in acidified drinking water (11-15 mg/kg/d) (for 126 days) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 9 8.0 % 2.0 6.0 ex vivo light microscopy with histochemistry 0.0 0 67960 751
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy Shiozawa M, et al., J Am Soc Nephrol 2000 Nov;11(11):2068-78. kidney glomerulus integrity trait male 91 days-98 days 21 3.2 % 0.39 1.8 ex vivo light microscopy 0.0 unilateral nephrectomy 39 days performed at 5 to 6 weeks of age 69158 1128
ACI.FHH-(D1Rat384-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 13.0 % 2.0 6.93 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68875 832
ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 12.0 % 2.0 6.93 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68877 832
ACI.FHH-(D1Rat384-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 14.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68879 832
ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then NG-nitroarginine methyl ester (10-21 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 9 29.0 % 4.0 12.0 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68885 832
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (9-16 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 11.0 % 1.0 3.46 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68886 832
ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (9-16 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 14.0 % 7.0 24.25 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68889 832
MWF kidney sclerotic glomeruli count to total glomeruli count ratio control condition (for 420 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. kidney glomerulus integrity trait male 420 days 10 99.0 % 0.63 2.0 ex vivo light microscopy with digital image analysis 0.0 0 100257 2459
SD kidney sclerotic glomeruli count to total glomeruli count ratio sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney glomerulus integrity trait male 0 days 6 1.9 % 0.49 1.2 ex vivo light microscopy with histochemistry 0.0 sham unx 28 days 101603 2602
MWF/Ztm kidney sclerotic glomeruli count to total glomeruli count ratio controlled lisinopril content drinking water (50 mg/l) (for 70 days) Remuzzi A, etal., Am J Kidney Dis. 1999 Oct;34(4):626-32. doi: 10.1016/S0272-6386(99)70385-9. kidney glomerulus integrity trait male 210 days 7 median 2.6 % ex vivo light microscopy with histochemistry left kidney 0.0 0 109987 3162
ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 30.0 % 3.0 10.39 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68876 832
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 8 5.0 % 1.0 2.83 ex vivo light microscopy with histochemistry 0.0 0 67956 751
ACI.FHH-(D1Rat324-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 8 9.0 % 3.0 8.49 ex vivo light microscopy with histochemistry 0.0 0 67958 751
ACI.FHH-(D1Rat324-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then controlled NG-nitroarginine methyl ester content in acidified drinking water (11-15 mg/kg/d) (for 126 days) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 8 41.0 % 9.0 25.46 ex vivo light microscopy with histochemistry 0.0 0 % glomerulosclerosis 67961 751
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 8 8.0 % 2.0 5.66 ex vivo light microscopy 0.0 0 67950 751
ACI.FHH-(D3Wox2-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 18.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67714 62
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 15.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67717 62
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy then NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 15.0 % 1.0 3.46 ex vivo light microscopy 0.0 0 67722 62
SD kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney glomerulus integrity trait male 0 days 8 31.0 % 5.66 16.0 ex vivo light microscopy with histochemistry 0.0 unx 28 days 101629 2602
SHR/N-cp kidney sclerotic glomeruli count to total glomeruli count ratio standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. kidney glomerulus integrity trait male 168 days-196 days 8 9.0 % 4.0 11.31 ex vivo light microscopy with histochemistry 0.0 0 101527 2601
MWF/Ztm kidney sclerotic glomeruli count to total glomeruli count ratio control condition Macconi D, etal., Am J Pathol. 2006 Jan;168(1):42-54. doi: 10.2353/ajpath.2006.050398. kidney glomerulus integrity trait male 280 days 12 47.0 % 8.0 27.71 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 108563 3034
ACI.FHH-(D1Rat298-D1Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 23.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67715 62
ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 21.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68880 832
ACI.FHH-(D17Rat117-D17Arb5)(D17Rat180-D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 7 2.0 % 1.0 2.65 ex vivo light microscopy 0.0 0 67951 751
ACI.FHH-(D17Rat117-D17Arb5)(D17Rat180-D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled NG-nitroarginine methyl ester content in acidified drinking water (8-13 mg/kg/d) (for 126 days) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 9 5.0 % 6.0 18.0 ex vivo light microscopy with histochemistry 0.0 0 67954 751
ACI.FHH-(D17Rat117-D17Arb5)(D17Rat180-D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 98 days 15 5.0 % 1.0 3.87 ex vivo light microscopy with histochemistry 0.0 0 68045 751
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 8.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68878 832
ACI.FHH-(D1Rat475-D1Rat90)(D3Rat84-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 14.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67711 62
ACI.FHH-(D1Rat298-D1Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy then NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 37.0 % 4.0 13.86 ex vivo light microscopy 0.0 0 67724 62
ACI.FHH-(D1Rat475-D1Rat90)(D3Rat84-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy then NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 5 64.0 % 11.0 24.6 ex vivo light microscopy 0.0 0 67725 62
ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then NG-nitroarginine methyl ester (10-21 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 2 59.0 % 11.0 15.56 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68884 832
WKY kidney sclerotic glomeruli count to total glomeruli count ratio control condition (for 280 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. kidney glomerulus integrity trait male 280 days 9 4.0 % 1.33 4.0 ex vivo light microscopy with digital image analysis 0.0 0 100256 2459
SD kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney glomerulus integrity trait male 0 days 6 25.3 % 4.53 11.1 ex vivo light microscopy with histochemistry 0.0 unx 28 days 101606 2602
SHR/N-cp kidney sclerotic glomeruli count to total glomeruli count ratio standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. kidney glomerulus integrity trait male 168 days-196 days 8 16.0 % 3.0 8.49 ex vivo light microscopy with histochemistry 0.0 0 101526 2601
SHR/N-cp kidney sclerotic glomeruli count to total glomeruli count ratio standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. kidney glomerulus integrity trait male 140 days-168 days 8 4.0 % 1.0 2.83 ex vivo light microscopy with histochemistry 0.0 0 101528 2601
MWF/Ztm kidney sclerotic glomeruli count to total glomeruli count ratio control condition Macconi D, etal., Am J Pathol. 2006 Jan;168(1):42-54. doi: 10.2353/ajpath.2006.050398. kidney glomerulus integrity trait male 140 days 13 19.0 % 8.0 28.84 ex vivo light microscopy with histochemistry and digital image analysis 0.0 0 108562 3034
ACI.FHH-(D3Wox2-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 13.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67709 62
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 11.0 % 1.0 3.46 ex vivo light microscopy 0.0 0 67712 62
ACI.FHH-(D1Rat475-D1Rat90)(D3Rat84-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 27.0 % 3.0 10.39 ex vivo light microscopy 0.0 0 67720 62
ACI.FHH-(D3Wox2-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy then NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 11 39.0 % 5.0 16.58 ex vivo light microscopy 0.0 0 67723 62
ACI.FHH-(D1Rat324-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 98 days 18 10.0 % 1.0 4.24 ex vivo light microscopy with histochemistry 0.0 0 68047 751
MWF kidney sclerotic glomeruli count to total glomeruli count ratio controlled lisinopril content drinking water (80-100 mg/l) (for 140 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. kidney glomerulus integrity trait male 420 days 10 85.0 % 2.53 8.0 ex vivo light microscopy with digital image analysis 0.0 0 100258 2459
ACI.FHH-(D1Rat324-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled NG-nitroarginine methyl ester content in acidified drinking water (8-13 mg/kg/d) (for 126 days) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 7 16.0 % 5.0 13.23 ex vivo light microscopy with histochemistry 0.0 0 67955 751
ACI.FHH-(D17Rat117-D17Arb5)(D17Rat180-D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 10 2.0 % 1.0 3.16 ex vivo light microscopy with histochemistry 0.0 0 67957 751
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 98 days 15 6.0 % 1.0 3.87 ex vivo light microscopy with histochemistry 0.0 0 68044 751
FHH/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 98 days 15 13.0 % 1.0 3.87 ex vivo light microscopy with histochemistry 0.0 0 68046 751
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 9.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67708 62
ACI.FHH-(D1Rat298-D1Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 14.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67710 62
ACI.FHH-(D1Rat475-D1Rat90)(D3Rat84-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (50-150 mg/l) Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 31.0 % 6.0 20.78 ex vivo light microscopy 0.0 0 67716 62
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 15.0 % 3.0 10.39 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68874 832
ACI.FHH-(D1Rat384-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (9-16 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 20.0 % 3.0 10.39 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68887 832
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then controlled NG-nitroarginine methyl ester content in acidified drinking water (11-15 mg/kg/d) (for 126 days) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 11 13.0 % 2.0 6.63 ex vivo light microscopy with histochemistry 0.0 0 67959 751
FHH/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy Shiozawa M, et al., J Am Soc Nephrol 2000 Nov;11(11):2068-78. kidney glomerulus integrity trait male 91 days-98 days 26 52.1 % 2.29 11.7 ex vivo light microscopy 0.0 unilateral nephrectomy 39 days performed at 5 to 6 weeks of age 69159 1128
ACI.FHH-(D1Rat384-D1Rat452)(D17Rat61-D1Arb5)(D17Rat51)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio control condition van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 8.0 % 1.0 3.46 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68881 832
ACI/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then NG-nitroarginine methyl ester (10-21 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 20.0 % 3.0 10.39 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68882 832
ACI.FHH-(D1Mit18-D1Mit8)(D14Mit11-D14Hmgc14b)(D14Rat65-D14Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio NG-nitroarginine methyl ester (9-16 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 12 33.0 % 3.0 10.39 ex vivo light microscopy 0.0 0 Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68888 832
ACI.FHH-(D1Rat298-D1Rat90)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 23.0 % 3.0 10.39 ex vivo light microscopy 0.0 0 67719 62
SD kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney glomerulus integrity trait male 0 days 7 37.2 % 10.02 26.5 ex vivo light microscopy with histochemistry 0.0 unx 28 days 101604 2602
MWF/Ztm kidney sclerotic glomeruli count to total glomeruli count ratio standard diet Remuzzi A, etal., Am J Kidney Dis. 1999 Oct;34(4):626-32. doi: 10.1016/S0272-6386(99)70385-9. kidney glomerulus integrity trait male 140 days 8 median 2.2 % ex vivo light microscopy with histochemistry left kidney 0.0 0 109985 3162
MWF/Ztm kidney sclerotic glomeruli count to total glomeruli count ratio standard diet Remuzzi A, etal., Am J Kidney Dis. 1999 Oct;34(4):626-32. doi: 10.1016/S0272-6386(99)70385-9. kidney glomerulus integrity trait male 210 days 10 median 18.6 % ex vivo light microscopy with histochemistry left kidney 0.0 0 109986 3162
ACI.FHH-(D3Wox2-D3Rat59)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio right nephrectomy Van Dijk SJ, et al., Kidney Int. 2006 kidney glomerulus integrity trait male 168 days-175 days 12 20.0 % 2.0 6.93 ex vivo light microscopy 0.0 0 67718 62
ACI.FHH-(D1Rat384-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy then NG-nitroarginine methyl ester (10-21 mg/kg/d) (for 126 days) van Dijk SJ, et al., Nephron Exp Nephrol. 2006;104(3):e96-e102. Epub 2006 Jul 12. kidney glomerulus integrity trait not specified 168 days-175 days 11 42.0 % 6.0 19.9 ex vivo light microscopy 0.0 unilateral nephrectomy 126 days Original CMO_ID, CMO:0001176, was merged into current ID and field automatically updated. 4-26-2013 68883 832
ACI.FHH-(D1Rat324-D1Rat156)/Eur kidney sclerotic glomeruli count to total glomeruli count ratio controlled hydrogen ion content drinking water (2.4-2.8 pH) Van Dijk SJ, et al., Nephron Exp Nephrol 2005 Jun 20;101(2):e59-e66. kidney glomerulus integrity trait male 173 days-180 days 8 15.0 % 3.0 8.49 ex vivo light microscopy 0.0 0 67952 751
MWF kidney sclerotic glomeruli count to total glomeruli count ratio control condition (for 280 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. kidney glomerulus integrity trait male 280 days 10 87.0 % 2.21 7.0 ex vivo light microscopy with digital image analysis 0.0 0 100255 2459
SD kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney glomerulus integrity trait male 0 days 8 26.0 % 3.89 11.0 ex vivo light microscopy with histochemistry 0.0 unx 28 days 101630 2602
SD kidney sclerotic glomeruli count to total glomeruli count ratio unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. kidney glomerulus integrity trait male 0 days 7 4.7 % 1.97 5.2 ex vivo light microscopy with histochemistry 0.0 unx 28 days 101605 2602