Phenominer Database Results (130 hits)

 

Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
LEW both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 6 7.91 g/kg 0.09 0.22 post excision weight measurement 0 0 64771 226
SS/Jr both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 16 12.1 g/kg 0.3 1.2 post excision weight measurement 0 0 64772 226
SS.LEW-(D16Rat12-D16Chm23)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 10 11.4 g/kg 0.2 0.63 post excision weight measurement 0 0 64781 226
SS.LEW-(D10Rat24-Igfbp4)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 5 10.0 g/kg 0.4 0.89 post excision weight measurement 0 0 64786 226
SS.LEW-(D8Rat56-D8Rat51)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 9 11.1 g/kg 0.4 1.2 post excision weight measurement 0 0 64788 226
PXO5-1/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 11 5.8 g/kg 0.1 0.33 post excision weight measurement 0.0 0 97126 1858
PXO3-2/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 9 6.0 g/kg 0.1 0.3 post excision weight measurement 0.0 0 97152 1858
SHR/OlaIpcv both kidneys wet weight to body weight ratio control condition (for 20 days) Pravenec M, et al., Physiol Res 2003;52(3):285-9. kidney mass male 28 days 5 4.73 g/kg 0.1 0.22 post excision weight measurement 0.0 0 97080 612
SHR.BN-(D5Wox12-D5Wox20)/Ipcv both kidneys wet weight to body weight ratio control condition Pravenec M, et al., Physiol Res 2003;52(3):285-9. kidney mass male 80 days-100 days 5 4.71 g/kg 0.1 0.22 post excision weight measurement 0.0 0 97081 612
SHRSP.WKY-(D3Mgh16-D3Rat80)/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 0 3.77 g/kg 0.12 post excision weight measurement 0.0 0 102122 2646
LH/Mav both kidneys wet weight to body weight ratio perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119 days 8 5.87 g/kg 0.1 0.28 post excision weight measurement 0.0 0 103421 2824
LH/Mav both kidneys wet weight to body weight ratio controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119 days 7 7.3 g/kg 0.09 0.24 post excision weight measurement 0.0 0 103423 2824
LH/MavRrrc both kidneys wet weight to body weight ratio vehicle control condition Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112 days 8 6.36 g/kg 0.08 0.23 post excision weight measurement 0.0 0 102693 2703
Crl:SD both kidneys wet weight to body weight ratio control condition (for 63 days) Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011. kidney mass male 63 days 5 0.1 g/kg 0.0 0.0 post excision weight measurement 0.0 0 105047 3010
SBH/Ygl both kidneys wet weight to body weight ratio sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. kidney mass male 16 days 8 2.6 g/kg 0.07 0.2 post excision weight measurement 0.0 0 n=8-15 106649 3035
Hsd:WI both kidneys wet weight to body weight ratio control condition Rothermund L, etal., J Hypertens. 2006 Sep 24(9). kidney mass male 100 days 16 5.7 g/kg 0.2 0.8 post excision weight measurement 0.0 0 108101 3115
SS.LEW-(D10Chm224-D10Chm6)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 11 11.0 g/kg 0.1 0.33 post excision weight measurement 0 0 64770 226
SS.LEW-(D18Chm91-D18Rat67)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 5 10.0 g/kg 0.4 0.89 post excision weight measurement 0 0 64774 226
SS.LEW-(D16Got3-D16Rat112)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 9 10.1 g/kg 0.2 0.6 post excision weight measurement 0 0 64780 226
SS.LEW-(D16Rat38-D16Chm66)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 8 10.5 g/kg 0.4 1.13 post excision weight measurement 0 0 64782 226
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. kidney mass male 114 days-118 days 6 10.45 g/kg 0.21 0.51 post excision weight measurement 0 0 65128 283
SHR/FubRkb both kidneys wet weight to body weight ratio control condition Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 kidney mass not specified 168 days 10 5.9 g/kg 0.05 0.16 post excision weight measurement 0.0 0 65364 117
MWF/FubRkb both kidneys wet weight to body weight ratio control condition Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 kidney mass not specified 168 days 18 5.44 g/kg 0.06 0.25 post excision weight measurement 0.0 0 65366 117
LEW/Rkb both kidneys wet weight to body weight ratio control condition Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. kidney mass not specified 126 days 8 5.93 g/kg 0.53 1.5 post excision weight measurement 0.0 0 67598 769
SHR/FubRkb both kidneys wet weight to body weight ratio control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. kidney mass female 168 days 10 6.15 g/kg 0.16 0.51 post excision weight measurement 0.0 0 68169 309
MWF/FubRkb both kidneys wet weight to body weight ratio control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. kidney mass female 168 days 18 5.78 g/kg 0.01 0.06 post excision weight measurement 0.0 0 68171 309
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm both kidneys wet weight to body weight ratio cold ambient air exposure (4 degrees C) (for 90 days) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. kidney mass not specified 112 days 10 8.17 g/kg 0.11 0.34 post excision weight measurement 0.0 0 68701 971
PXO8-1/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 10 5.6 g/kg 0.04 0.13 post excision weight measurement 0.0 0 97123 1858
PXO2/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 11 5.7 g/kg 0.1 0.33 post excision weight measurement 0.0 0 97125 1858
PXO7-1/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 8 5.8 g/kg 0.1 0.28 post excision weight measurement 0.0 0 97127 1858
PXO6-1/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 10 6.0 g/kg 0.1 0.32 post excision weight measurement 0.0 0 97151 1858
SHRSP.WKY-(D3Mgh16-D3Wox3)/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 7 3.77 g/kg 0.15 0.4 post excision weight measurement 0.0 0 102161 2646
SHRSP.WKY-(D3Mgh16-D3Rat114)/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 0 3.65 g/kg 0.2 post excision weight measurement 0.0 0 102120 2646
PXO6-3/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 10 5.9 g/kg 0.1 0.32 post excision weight measurement 0.0 0 97148 1858
FHH-Nr4a1m1Mcwi both kidneys wet weight to body weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. kidney mass male 112 days 6 10.3 g/kg 0.14 0.34 post excision weight measurement 0.0 0 99460 2318
LH/Mav both kidneys wet weight to body weight ratio streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112 days 9 7.02 g/kg 0.18 0.54 post excision weight measurement 0.0 0 102695 2703
SHRSP.WKY-(D3Mgh16-D3Mit10)/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 0 4.2 g/kg 0.62 post excision weight measurement 0.0 0 102125 2646
SHR/N-cp both kidneys wet weight to body weight ratio standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. kidney mass male 168 days-196 days 8 1.88 g/kg 0.1 0.28 post excision weight measurement 0.0 0 101523 2601
SD-Abcb11em1Sage both kidneys wet weight to body weight ratio control condition (for 63 days) Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011. kidney mass male 63 days 5 0.09 g/kg 0.0 0.01 post excision weight measurement 0.0 0 105048 3010
WKY/N both kidneys wet weight to body weight ratio control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney mass male 126 days-182 days 0 6.1 g/kg 0.4 post excision weight measurement kidney 0.0 0 107533 3090
SS.LEW-(D18Rat61-D18Rat45)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 6 10.1 g/kg 0.2 0.49 post excision weight measurement 0 0 64776 226
SS.LEW-(D17Chm14-D17Rat181)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 5 9.7 g/kg 0.2 0.45 post excision weight measurement 0 0 64779 226
SS.LEW-(D2Rat199-D2Mco17)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 8 11.4 g/kg 0.6 1.7 post excision weight measurement 0 0 64799 226
SHR/OlaIpcv both kidneys wet weight to body weight ratio control condition (for 20 days) Pravenec M, et al., Physiol Res 2003;52(3):285-9. kidney mass male 80 days-100 days 10 8.07 g/kg 0.36 1.14 post excision weight measurement 0 0 65507 612
MWF-Chr 6SHR/Rkb both kidneys wet weight to body weight ratio control condition Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 kidney mass not specified 168 days 19 5.62 g/kg 0.18 0.78 post excision weight measurement 0.0 0 65365 117
SS.SR-(D3Arb14-D3Mco36)/Mco both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. kidney mass male 114 days-118 days 5 10.6 g/kg 0.13 0.29 post excision weight measurement 0 0 65126 283
COP/OlaHsd both kidneys wet weight to body weight ratio control condition Ways JA, et al., Physiol Genomics. 2006 Dec 19;. kidney mass not specified 105 days 15 6.8 g/kg 0.14 0.54 post excision weight measurement 0.0 0 68521 933
COP.DA-(D16Rat12-D16Rat90)/Mco both kidneys wet weight to body weight ratio control condition Ways JA, et al., Physiol Genomics. 2006 Dec 19;. kidney mass not specified 105 days 8 6.49 g/kg 0.18 0.51 post excision weight measurement 0.0 0 68523 933
PXO4/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 9 6.3 g/kg 0.1 0.3 post excision weight measurement 0.0 0 97153 1858
BXH2/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 18 6.3 g/kg 0.1 0.42 post excision weight measurement 0.0 0 97120 1858
LL/Mav both kidneys wet weight to body weight ratio streptozotocin (100 mg/kg) Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. kidney mass male 112 days 18 6.61 g/kg 0.08 0.34 post excision weight measurement 0.0 0 102763 2721
LH/Mav both kidneys wet weight to body weight ratio streptozotocin (75 mg/kg) Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. kidney mass male 112 days 14 6.65 g/kg 0.08 0.3 post excision weight measurement 0.0 0 102765 2721
LH/Mav both kidneys wet weight to body weight ratio perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119 days 8 6.22 g/kg 0.21 0.59 post excision weight measurement 0.0 0 103420 2824
FHH-Nr4a1m1Mcwi both kidneys wet weight to body weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. kidney mass male 56 days 6 10.3 g/kg 0.14 0.34 post excision weight measurement 0.0 0 99458 2318
FHH-Nr4a1m1Mcwi both kidneys wet weight to body weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. kidney mass male 168 days 6 11.0 g/kg 0.53 1.3 post excision weight measurement 0.0 0 99462 2318
SR/JrIpcv both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) Hojnż S, et al., Physiol Res. 2005;54(2):201-6. kidney mass male 0 days 0 7.24 g/kg 0.1 post excision weight measurement 0.0 0 102393 2688
SHRSP.WKY-(D3Mgh16-rs197649383)/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 0 4.25 g/kg 0.7 post excision weight measurement 0.0 0 102124 2646
SHR/N-cp both kidneys wet weight to body weight ratio standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. kidney mass male 168 days-196 days 8 1.67 g/kg 0.1 0.28 post excision weight measurement 0.0 0 101524 2601
SS-Kcnj1em1Kasu+/+ both kidneys wet weight to body weight ratio control condition (for 13 days) Zhou X, et al., Hypertension. 2013 Aug;62(2):288-94. doi: 10.1161/HYPERTENSIONAHA.111.01051. Epub 2013 Jun 10. kidney mass male 13 days 6 8.6 g/kg 1.1 2.69 post excision weight measurement 0.0 0 104421 2948
SS-Kcnj1em1Kasu+/- both kidneys wet weight to body weight ratio control condition (for 13 days) Zhou X, et al., Hypertension. 2013 Aug;62(2):288-94. doi: 10.1161/HYPERTENSIONAHA.111.01051. Epub 2013 Jun 10. kidney mass male 13 days 6 8.8 g/kg 0.4 0.98 post excision weight measurement 0.0 0 104422 2948
SS-Kcnj1em1Kasu-/- both kidneys wet weight to body weight ratio control condition (for 13 days) Zhou X, et al., Hypertension. 2013 Aug;62(2):288-94. doi: 10.1161/HYPERTENSIONAHA.111.01051. Epub 2013 Jun 10. kidney mass male 13 days 5 13.4 g/kg 0.6 1.34 post excision weight measurement 0.0 0 104423 2948
SBN/Ygl both kidneys wet weight to body weight ratio sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. kidney mass male 16 days 8 2.4 g/kg 0.03 0.08 post excision weight measurement 0.0 0 n=8-15 106646 3035
SHRSP/A3N both kidneys wet weight to body weight ratio controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney mass male 126 days-182 days 0 13.0 g/kg 0.7 post excision weight measurement kidney 0.0 0 107535 3090
MWF/FubRkb both kidneys wet weight to body weight ratio control condition Rothermund L, etal., J Hypertens. 2006 Sep 24(9). kidney mass male 100 days 10 6.2 g/kg 0.1 0.32 post excision weight measurement 0.0 0 108102 3115
SS.LEW-(D18Chm56-D18Rat55)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 5 11.5 g/kg 0.6 1.34 post excision weight measurement 0 0 64773 226
SS.LEW-(D10Chm128-D10Chm169)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 8 10.0 g/kg 0.3 0.85 post excision weight measurement 0 0 64783 226
SS.LEW-(D10Chm128-D10Chm121)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 9 10.5 g/kg 0.5 1.5 post excision weight measurement 0 0 64785 226
SS.LEW-(D10Rat27-Igfbp4)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 7 10.9 g/kg 0.4 1.06 post excision weight measurement 0 0 64787 226
SS.LEW-(D3Rat61-D3Wox1)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 7 10.1 g/kg 0.4 1.06 post excision weight measurement 0 0 64790 226
SS.LEW-(D3Got33-D3Chm68)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 10 10.4 g/kg 0.2 0.63 post excision weight measurement 0 0 64791 226
SS.LEW-(D3Rat52-D3Rat130)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 7 9.5 g/kg 0.2 0.53 post excision weight measurement 0 0 64793 226
SS.MNS-(D2Chm25-Fgg)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 9 10.6 g/kg 0.2 0.6 post excision weight measurement 0 0 64794 226
SS.MNS-(D2Wox27-Adh1)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 5 10.3 g/kg 0.2 0.45 post excision weight measurement 0 0 64796 226
MWF-Chr 6SHR/Rkb both kidneys wet weight to body weight ratio control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. kidney mass female 168 days 20 6.06 g/kg 0.16 0.72 post excision weight measurement 0.0 0 12764 309
ISIAH both kidneys wet weight to body weight ratio control condition Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. kidney mass not specified 180 days 11 7.0 g/kg 0.1 0.33 post excision weight measurement 0.0 0 68058 835
DA/OlaHsd both kidneys wet weight to body weight ratio control condition Ways JA, et al., Physiol Genomics. 2006 Dec 19;. kidney mass not specified 105 days 12 7.73 g/kg 0.13 0.45 post excision weight measurement 0.0 0 68522 933
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm both kidneys wet weight to body weight ratio control condition Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. kidney mass not specified 112 days 10 7.69 g/kg 0.11 0.35 post excision weight measurement 0.0 0 68699 971
SHR.BN-(D8Mit5-D8Mgh6)/Ipcv both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 13 6.2 g/kg 0.1 0.36 post excision weight measurement 0.0 0 97121 1858
PXO6-2/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 8 5.6 g/kg 0.1 0.28 post excision weight measurement 0.0 0 97124 1858
PXO8-2/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 13 5.5 g/kg 0.1 0.36 post excision weight measurement 0.0 0 97122 1858
PXO1/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 11 5.9 g/kg 0.1 0.33 post excision weight measurement 0.0 0 97149 1858
PXO10/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 12 7.3 g/kg 0.1 0.35 post excision weight measurement 0.0 0 97155 1858
PXO5-2/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 10 6.0 g/kg 0.1 0.32 post excision weight measurement 0.0 0 97156 1858
SHRSP/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 0 4.11 g/kg 0.25 post excision weight measurement 0.0 0 102118 2646
SR/NEisSlc both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. kidney mass male 126 days 8 3.53 g/kg 0.04 0.11 post excision weight measurement 0.0 0 102322 2684
SS/NEisSlc both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. kidney mass male 126 days 8 4.55 g/kg 0.06 0.17 post excision weight measurement 0.0 0 102324 2684
FHH/EurMcwi both kidneys wet weight to body weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. kidney mass male 56 days 6 9.2 g/kg 0.27 0.66 post excision weight measurement 0.0 0 99457 2318
FHH/EurMcwi both kidneys wet weight to body weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. kidney mass male 112 days 6 9.2 g/kg 0.27 0.66 post excision weight measurement 0.0 0 99459 2318
LH/Mav both kidneys wet weight to body weight ratio controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119 days 6 7.22 g/kg 0.34 0.83 post excision weight measurement 0.0 0 103422 2824
LL/Mav both kidneys wet weight to body weight ratio vehicle control condition Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. kidney mass male 112 days 9 6.08 g/kg 0.07 0.21 post excision weight measurement 0.0 0 102762 2721
LL/Mav both kidneys wet weight to body weight ratio vehicle control condition Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112 days 13 6.53 g/kg 0.04 0.14 post excision weight measurement 0.0 0 102692 2703
LH/Mav both kidneys wet weight to body weight ratio streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112 days 7 8.05 g/kg 0.24 0.63 post excision weight measurement 0.0 0 102697 2703
SHR/N-cp both kidneys wet weight to body weight ratio standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. kidney mass male 140 days-168 days 8 1.83 g/kg 0.31 0.88 post excision weight measurement 0.0 0 101525 2601
SBN/Ygl both kidneys wet weight to body weight ratio deoxycorticosterone acetate (75 mg) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and darusentan (50 mg/kg/d) (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. kidney mass male 16 days 8 2.7 g/kg 0.08 0.23 post excision weight measurement 0.0 0 n=8-15 106648 3035
SBH/Ygl both kidneys wet weight to body weight ratio deoxycorticosterone acetate (75 mg) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. kidney mass male 16 days 8 3.0 g/kg 0.08 0.23 post excision weight measurement 0.0 0 n=8-15 106650 3035
SHRSP/A3N both kidneys wet weight to body weight ratio control condition (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney mass male 126 days-182 days 0 7.1 g/kg 0.2 post excision weight measurement kidney 0.0 0 107534 3090
SS.LEW-(D18Chm41-D18Rat92)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 5 10.1 g/kg 0.4 0.89 post excision weight measurement 0 0 64775 226
SS.LEW-(D17Chm9-D17Rat97)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 10 10.3 g/kg 0.4 1.26 post excision weight measurement 0 0 64777 226
SS.LEW-(D17Rat65-D17Chm2)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 5 10.2 g/kg 0.4 0.89 post excision weight measurement 0 0 64778 226
SS.LEW-(D10Chm10-D10Rat11)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 7 10.1 g/kg 0.2 0.53 post excision weight measurement 0 0 64784 226
SS.LEW-(D8Chm14-D8Rat16)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 7 9.5 g/kg 0.2 0.53 post excision weight measurement 0 0 64789 226
SS.LEW-(D3Mco21-D3Rat17)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 4 9.5 g/kg 0.3 0.6 post excision weight measurement 0 0 64792 226
SS.MNS-(D2Chm51-D2Rat341)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 8 9.9 g/kg 0.2 0.57 post excision weight measurement 0 0 64795 226
SS.MNS-(D2Chm25-D2Rat131)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 5 9.8 g/kg 0.3 0.67 post excision weight measurement 0 0 64797 226
SS.MNS-(D2Rat183-D2Chm113)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 8 9.9 g/kg 0.2 0.57 post excision weight measurement 0 0 64798 226
SS.LEW-(D2Rat18-D2Chm277)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 6 12.2 g/kg 0.3 0.73 post excision weight measurement 0 0 64800 226
SHR.BN-(D5Wox12-D5Wox20)/Ipcv both kidneys wet weight to body weight ratio control condition Pravenec M, et al., Physiol Res 2003;52(3):285-9. kidney mass male 80 days-100 days 8 6.9 g/kg 0.24 0.68 post excision weight measurement 0 0 65508 612
HTG both kidneys wet weight to body weight ratio losartan (10 mg/kg) (for 0.2 hours) then pentolinium (5 mg/kg) (for 0.1 hours) then NG-nitroarginine methyl ester (30 mg/kg) (for 0.3 hours) Ueno T, et al., Physiol Res 2003;52(6):689-700. kidney mass not specified 0 days 10 continuous mean 5.92 g/kg post excision weight measurement 0 0 65418 568
LEW/Cub both kidneys wet weight to body weight ratio losartan (10 mg/kg) (for 0.2 hours) then pentolinium (5 mg/kg) (for 0.1 hours) then NG-nitroarginine methyl ester (30 mg/kg) (for 0.3 hours) Ueno T, et al., Physiol Res 2003;52(6):689-700. kidney mass not specified 0 days 9 serial mean 6.84 g/kg post excision weight measurement 0 0 65427 568
MWF/FubRkb both kidneys wet weight to body weight ratio control condition Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. kidney mass not specified 126 days 8 5.01 g/kg 0.36 1.02 post excision weight measurement 0.0 0 67597 769
SS/Jr both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. kidney mass male 114 days-118 days 4 11.87 g/kg 0.92 1.84 post excision weight measurement 0 0 65100 283
SS.LEW-(D18Rat30-D18Chm29)/Ayd both kidneys wet weight to body weight ratio controlled sodium content diet (2 %) (between 35 and 98 days) Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 kidney mass male 98 days 8 10.4 g/kg 0.2 0.57 post excision weight measurement 0 0 64801 226
SS.SR-(D7Mco19-D7Mco7)/Jr both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. kidney mass male 114 days-118 days 3 10.53 g/kg 0.18 0.31 post excision weight measurement 0 0 65127 283
WAG/RijKyo both kidneys wet weight to body weight ratio control condition Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. kidney mass not specified 180 days 9 5.2 g/kg 0.1 0.3 post excision weight measurement 0.0 0 68057 835
COP.DA-(D3Rat233-D3Mgh14)/Mco both kidneys wet weight to body weight ratio control condition Ways JA, et al., Physiol Genomics. 2006 Dec 19;. kidney mass not specified 105 days 18 6.37 g/kg 0.11 0.47 post excision weight measurement 0.0 0 68524 933
PXO9/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 9 6.0 g/kg 0.1 0.3 post excision weight measurement 0.0 0 97150 1858
PXO3-1/Cub both kidneys wet weight to body weight ratio controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. kidney mass male 127 days 10 6.3 g/kg 0.1 0.32 post excision weight measurement 0.0 0 97154 1858
WKY/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 0 2.87 g/kg 0.23 post excision weight measurement 0.0 0 102119 2646
SHRSP.WKY-(D3Wox20-D3Rat114)/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 6 3.78 g/kg 0.18 0.44 post excision weight measurement 0.0 0 102121 2646
SHRSP.WKY-(D3Mgh16-rs65433898)/Gcrc both kidneys wet weight to body weight ratio vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. kidney mass male 126 days 0 4.16 g/kg 0.4 post excision weight measurement 0.0 0 102123 2646
SS/NEisSlc both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. kidney mass male 126 days 8 5.19 g/kg 0.19 0.54 post excision weight measurement 0.0 0 102323 2684
LH/Mav both kidneys wet weight to body weight ratio controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119 days 7 6.81 g/kg 0.19 0.5 post excision weight measurement 0.0 0 103419 2824
LH/Mav both kidneys wet weight to body weight ratio vehicle control condition Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. kidney mass male 112 days 11 6.24 g/kg 0.07 0.23 post excision weight measurement 0.0 0 102764 2721
FHH/EurMcwi both kidneys wet weight to body weight ratio control condition Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. kidney mass male 168 days 6 8.1 g/kg 0.18 0.44 post excision weight measurement 0.0 0 99461 2318
LH/Mav both kidneys wet weight to body weight ratio streptozotocin (75 mg/kg) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112 days 8 6.95 g/kg 0.23 0.65 post excision weight measurement 0.0 0 102694 2703
LH/Mav both kidneys wet weight to body weight ratio streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112 days 11 6.44 g/kg 0.14 0.46 post excision weight measurement 0.0 0 102696 2703
SS/JrIpcv both kidneys wet weight to body weight ratio controlled sodium content diet (0.3 %) Hojnż S, et al., Physiol Res. 2005;54(2):201-6. kidney mass male 0 days 0 6.39 g/kg 0.12 post excision weight measurement 0.0 0 102394 2688
SBN/Ygl both kidneys wet weight to body weight ratio deoxycorticosterone acetate (75 mg) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. kidney mass male 16 days 8 2.6 g/kg 0.05 0.14 post excision weight measurement 0.0 0 n=8-15 106647 3035
SBN/Ygl both kidneys wet weight to body weight ratio deoxycorticosterone acetate (75 mg) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and darusentan (50 mg/kg/d) (for 56 days) Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. kidney mass male 16 days 8 3.2 g/kg 0.06 0.17 post excision weight measurement 0.0 0 n=8-15 106651 3035
SHRSP/A3N both kidneys wet weight to body weight ratio controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and eprosartan (60 mg/kg/d) (between 42 and 77 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. kidney mass male 126 days-182 days 0 8.8 g/kg 0.4 post excision weight measurement kidney 0.0 0 107536 3090