SS/Jr |
receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio |
Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
50.61 |
% |
5.29 |
18.33 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69069 |
1096 |
SS.MNS-(D2Mit6-Adh1)/Ayd |
heart right ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart right ventricle DNA amount |
male |
98 days
| 5 |
1.13 |
ug/g |
0.05 |
0.11 |
spectrophotometry |
0.0 |
0 |
|
|
69040 |
1096 |
SS.MNS-(D2Mit6-D2Rat166)/Ayd |
heart right ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart right ventricle DNA amount |
male |
98 days
| 4 |
0.5 |
ug/g |
0.09 |
0.18 |
spectrophotometry |
0.0 |
0 |
|
|
69041 |
1096 |
SS/Jr |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
-7.6 |
null |
0.05 |
0.17 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
EC50 value is probably moles/liter |
69058 |
1096 |
SS.MNS-(D2Mit6-Adh1)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
arterial blood pressure trait |
male |
68 days-98 days |
5 |
120.0 |
mmHg |
|
|
radiotelemetry |
0.0 |
0 |
|
|
69026 |
1096 |
SS/Jr |
logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) |
Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
-8.22 |
null |
0.26 |
0.9 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69067 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) |
Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
-7.2 |
null |
0.31 |
1.12 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69072 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
blood vessel contractile force measurement |
Kreb's solution perfusate then potassium chloride solution (40 mmol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
1.62 |
g |
0.09 |
0.32 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69049 |
1096 |
SS/Jr |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
arterial blood pressure trait |
male |
68 days-98 days |
10 |
170.0 |
mmHg |
|
|
radiotelemetry |
0.0 |
0 |
|
|
69025 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
aorta smooth muscle cell count per unit vessel length |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
blood vessel smooth muscle cell quantity |
male |
98 days
| 8 |
134.0 |
/um |
21.0 |
59.4 |
ex vivo light microscopy with digital image analysis |
0.0 |
0 |
|
/um - calculated aortic smooth muscle cell count |
69032 |
1096 |
SS/Jr |
receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio |
Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
141.72 |
% |
7.73 |
26.78 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69056 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
-7.41 |
null |
0.16 |
0.58 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
EC50 value is probably moles/liter |
69059 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
blood vessel contractile force measurement |
Kreb's solution perfusate then potassium chloride solution (40 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
1.6 |
g |
0.12 |
0.43 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69051 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
heart right ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart right ventricle DNA amount |
male |
98 days
| 5 |
1.2 |
ug/g |
0.09 |
0.2 |
spectrophotometry |
0.0 |
0 |
|
|
69042 |
1096 |
SS/Jr |
blood vessel contractile force measurement |
Kreb's solution perfusate then potassium chloride solution (40 mmol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
1.59 |
g |
0.11 |
0.38 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
|
|
69048 |
1096 |
SS/Jr |
blood vessel contractile force measurement |
Kreb's solution perfusate then potassium chloride solution (40 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
1.39 |
g |
0.06 |
0.21 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69050 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
heart left ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart left ventricle DNA amount |
male |
98 days
| 5 |
5.0 |
ug/g |
0.5 |
1.12 |
spectrophotometry |
0.0 |
0 |
|
|
69037 |
1096 |
SS.MNS-(D2Mit6-D2Rat166)/Ayd |
aorta smooth muscle cell count per unit vessel length |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
blood vessel smooth muscle cell quantity |
male |
98 days
| 8 |
170.0 |
/um |
11.0 |
31.11 |
ex vivo light microscopy with digital image analysis |
0.0 |
0 |
|
/um - calculated aortic smooth muscle cell count |
69031 |
1096 |
SS/Jr |
aorta smooth muscle cell count per unit vessel length |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
blood vessel smooth muscle cell quantity |
male |
98 days
| 10 |
90.0 |
/um |
4.0 |
12.65 |
ex vivo light microscopy with digital image analysis |
0.0 |
0 |
|
/um - calculated aortic smooth muscle cell count |
69034 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio |
Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
26.63 |
% |
4.0 |
14.42 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69070 |
1096 |
SS.MNS-(Mme-D2Rat131)/Ayd |
heart right ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart right ventricle DNA amount |
male |
98 days
| 5 |
1.1 |
ug/g |
0.2 |
0.45 |
spectrophotometry |
0.0 |
0 |
|
|
69043 |
1096 |
SS/Jr |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
Kreb's solution perfusate then phenylephrine (1-100 mmol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
-7.26 |
null |
0.06 |
0.21 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
EC50 value is probably moles/liter |
69054 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio |
Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
19.33 |
% |
3.67 |
13.23 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69066 |
1096 |
SS/Jr |
heart right ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart right ventricle DNA amount |
male |
98 days
| 11 |
1.1 |
ug/g |
0.1 |
0.33 |
spectrophotometry |
0.0 |
0 |
|
|
69044 |
1096 |
SS.MNS-(Mme-D2Rat131)/Ayd |
aorta smooth muscle cell count per unit vessel length |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
blood vessel smooth muscle cell quantity |
male |
98 days
| 4 |
71.0 |
/um |
4.0 |
8.0 |
ex vivo light microscopy with digital image analysis |
0.0 |
0 |
|
/um - calculated aortic smooth muscle cell count |
69033 |
1096 |
SS.MNS-(D2Mit6-Adh1)/Ayd |
heart left ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart left ventricle DNA amount |
male |
98 days
| 5 |
3.0 |
ug/g |
0.2 |
0.45 |
spectrophotometry |
0.0 |
0 |
DNA extraction method |
|
69035 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
arterial blood pressure trait |
male |
68 days-98 days |
9 |
168.0 |
mmHg |
|
|
radiotelemetry |
0.0 |
0 |
|
|
69028 |
1096 |
SS/Jr |
heart left ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart left ventricle DNA amount |
male |
98 days
| 11 |
5.8 |
ug/g |
0.6 |
1.99 |
spectrophotometry |
0.0 |
0 |
|
|
69039 |
1096 |
SS/Jr |
receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio |
Kreb's solution perfusate then phenylephrine (1-100 mmol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
104.06 |
% |
4.7 |
16.28 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69052 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio |
Kreb's solution perfusate then phenylephrine (1-100 mmol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
100.16 |
% |
5.63 |
20.3 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69053 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
Kreb's solution perfusate then phenylephrine (1-100 mmol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
-6.96 |
null |
0.17 |
0.61 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
EC50 value is probably moles/liter |
69055 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio |
Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
143.03 |
% |
6.62 |
23.87 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69057 |
1096 |
SS/Jr |
receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio |
Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
34.85 |
% |
2.94 |
10.18 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69065 |
1096 |
SS.MNS-(D2Mit6-D2Rat303)/Ayd |
logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) |
Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 13 |
-7.86 |
null |
0.27 |
0.97 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69068 |
1096 |
SS/Jr |
logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) |
Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) then NG-nitroarginine methyl ester (100 umol/l) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
vasoconstriction trait |
male |
98 days
| 12 |
-7.92 |
null |
0.36 |
1.25 |
tissue force analysis utilizing a force transducer |
0.0 |
0 |
isometric force transducer |
|
69071 |
1096 |
SS.MNS-(D2Mit6-D2Rat166)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
arterial blood pressure trait |
male |
68 days-98 days |
9 |
148.0 |
mmHg |
|
|
radiotelemetry |
0.0 |
0 |
|
|
69027 |
1096 |
SS.MNS-(Mme-D2Rat131)/Ayd |
mean arterial blood pressure |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
arterial blood pressure trait |
male |
68 days-98 days |
5 |
122.0 |
mmHg |
|
|
radiotelemetry |
0.0 |
0 |
|
|
69029 |
1096 |
SS.MNS-(D2Mit6-Adh1)/Ayd |
aorta smooth muscle cell count per unit vessel length |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
blood vessel smooth muscle cell quantity |
male |
98 days
| 5 |
58.0 |
/um |
9.0 |
20.12 |
ex vivo light microscopy with digital image analysis |
0.0 |
0 |
|
|
69030 |
1096 |
SS.MNS-(Mme-D2Rat131)/Ayd |
heart left ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart left ventricle DNA amount |
male |
98 days
| 5 |
3.7 |
ug/g |
0.3 |
0.67 |
spectrophotometry |
0.0 |
0 |
|
|
69038 |
1096 |
SS.MNS-(D2Mit6-D2Rat166)/Ayd |
heart left ventricle deoxyribonucleic acid level to body weight ratio |
controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) |
Dutil J, et al., Physiol Genomics 2005 Mar 1;. |
heart left ventricle DNA amount |
male |
98 days
| 4 |
5.0 |
ug/g |
0.5 |
1.0 |
spectrophotometry |
0.0 |
0 |
|
|
69036 |
1096 |