Phenominer Database Results (40 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
SS.MNS-(D2Mit6-D2Rat303)/Ayd logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 -7.86 null 0.27 0.97 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69068 1096
SS/Jr blood vessel contractile force measurement Kreb's solution perfusate then potassium chloride solution (40 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 1.39 g 0.06 0.21 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69050 1096
SS/Jr aorta smooth muscle cell count per unit vessel length controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. blood vessel smooth muscle cell quantity male 98 days 10 90.0 /um 4.0 12.65 ex vivo light microscopy with digital image analysis 0.0 0 /um - calculated aortic smooth muscle cell count 69034 1096
SS/Jr heart right ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart right ventricle DNA amount male 98 days 11 1.1 ug/g 0.1 0.33 spectrophotometry 0.0 0 69044 1096
SS/Jr blood vessel contractile force measurement Kreb's solution perfusate then potassium chloride solution (40 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 1.59 g 0.11 0.38 tissue force analysis utilizing a force transducer 0.0 0 69048 1096
SS/Jr receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 34.85 % 2.94 10.18 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69065 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 19.33 % 3.67 13.23 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69066 1096
SS.MNS-(D2Mit6-D2Rat166)/Ayd mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. arterial blood pressure trait male 68 days-98 days 9 148.0 mmHg radiotelemetry 0.0 0 69027 1096
SS.MNS-(D2Mit6-Adh1)/Ayd heart left ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart left ventricle DNA amount male 98 days 5 3.0 ug/g 0.2 0.45 spectrophotometry 0.0 0 DNA extraction method 69035 1096
SS.MNS-(D2Mit6-Adh1)/Ayd mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. arterial blood pressure trait male 68 days-98 days 5 120.0 mmHg radiotelemetry 0.0 0 69026 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. arterial blood pressure trait male 68 days-98 days 9 168.0 mmHg radiotelemetry 0.0 0 69028 1096
SS/Jr heart left ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart left ventricle DNA amount male 98 days 11 5.8 ug/g 0.6 1.99 spectrophotometry 0.0 0 69039 1096
SS/Jr receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 141.72 % 7.73 26.78 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69056 1096
SS/Jr logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then phenylephrine (1-100 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 -7.26 null 0.06 0.21 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer EC50 value is probably moles/liter 69054 1096
SS/Jr receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 50.61 % 5.29 18.33 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69069 1096
SS/Jr logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) then NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 -7.92 null 0.36 1.25 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69071 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd blood vessel contractile force measurement Kreb's solution perfusate then potassium chloride solution (40 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 1.62 g 0.09 0.32 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69049 1096
SS/Jr mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. arterial blood pressure trait male 68 days-98 days 10 170.0 mmHg radiotelemetry 0.0 0 69025 1096
SS.MNS-(Mme-D2Rat131)/Ayd mean arterial blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. arterial blood pressure trait male 68 days-98 days 5 122.0 mmHg radiotelemetry 0.0 0 69029 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd heart left ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart left ventricle DNA amount male 98 days 5 5.0 ug/g 0.5 1.12 spectrophotometry 0.0 0 69037 1096
SS.MNS-(D2Mit6-D2Rat166)/Ayd aorta smooth muscle cell count per unit vessel length controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. blood vessel smooth muscle cell quantity male 98 days 8 170.0 /um 11.0 31.11 ex vivo light microscopy with digital image analysis 0.0 0 /um - calculated aortic smooth muscle cell count 69031 1096
SS.MNS-(Mme-D2Rat131)/Ayd heart right ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart right ventricle DNA amount male 98 days 5 1.1 ug/g 0.2 0.45 spectrophotometry 0.0 0 69043 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 -7.2 null 0.31 1.12 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69072 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd heart right ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart right ventricle DNA amount male 98 days 5 1.2 ug/g 0.09 0.2 spectrophotometry 0.0 0 69042 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then phenylephrine (1-100 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 -6.96 null 0.17 0.61 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer EC50 value is probably moles/liter 69055 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 143.03 % 6.62 23.87 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69057 1096
SS.MNS-(D2Mit6-Adh1)/Ayd aorta smooth muscle cell count per unit vessel length controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. blood vessel smooth muscle cell quantity male 98 days 5 58.0 /um 9.0 20.12 ex vivo light microscopy with digital image analysis 0.0 0 69030 1096
SS.MNS-(Mme-D2Rat131)/Ayd heart left ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart left ventricle DNA amount male 98 days 5 3.7 ug/g 0.3 0.67 spectrophotometry 0.0 0 69038 1096
SS/Jr logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 -8.22 null 0.26 0.9 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69067 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd blood vessel contractile force measurement Kreb's solution perfusate then potassium chloride solution (40 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 1.6 g 0.12 0.43 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69051 1096
SS.MNS-(D2Mit6-Adh1)/Ayd heart right ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart right ventricle DNA amount male 98 days 5 1.13 ug/g 0.05 0.11 spectrophotometry 0.0 0 69040 1096
SS.MNS-(D2Mit6-D2Rat166)/Ayd heart right ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart right ventricle DNA amount male 98 days 4 0.5 ug/g 0.09 0.18 spectrophotometry 0.0 0 69041 1096
SS/Jr receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then phenylephrine (1-100 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 104.06 % 4.7 16.28 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69052 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then phenylephrine (1-100 mmol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 100.16 % 5.63 20.3 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69053 1096
SS/Jr logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 12 -7.6 null 0.05 0.17 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer EC50 value is probably moles/liter 69058 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd aorta smooth muscle cell count per unit vessel length controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. blood vessel smooth muscle cell quantity male 98 days 8 134.0 /um 21.0 59.4 ex vivo light microscopy with digital image analysis 0.0 0 /um - calculated aortic smooth muscle cell count 69032 1096
SS.MNS-(Mme-D2Rat131)/Ayd aorta smooth muscle cell count per unit vessel length controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. blood vessel smooth muscle cell quantity male 98 days 4 71.0 /um 4.0 8.0 ex vivo light microscopy with digital image analysis 0.0 0 /um - calculated aortic smooth muscle cell count 69033 1096
SS.MNS-(D2Mit6-D2Rat166)/Ayd heart left ventricle deoxyribonucleic acid level to body weight ratio controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days) Dutil J, et al., Physiol Genomics 2005 Mar 1;. heart left ventricle DNA amount male 98 days 4 5.0 ug/g 0.5 1.0 spectrophotometry 0.0 0 69036 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio Kreb's solution perfusate then angiotensin II (0.3-300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 26.63 % 4.0 14.42 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer 69070 1096
SS.MNS-(D2Mit6-D2Rat303)/Ayd logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) Kreb's solution perfusate then phenylephrine (1-100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) Dutil J, et al., Physiol Genomics 2005 Mar 1;. vasoconstriction trait male 98 days 13 -7.41 null 0.16 0.58 tissue force analysis utilizing a force transducer 0.0 0 isometric force transducer EC50 value is probably moles/liter 69059 1096