Study ID,Study,Experiment Name,Experiment Notes,Strain Ont ID,Strain,Sex,Age,# of Animals,Sample Notes,Clinical Measurement Ont ID,Phenotype,Formula,Clinical Measurement Notes,Average Type,Value,Units,SEM,SD,Method Ont ID,Method,Method Site,Method Duration,Method Notes,Post Insult Type,Post Insult Time Value,Post Insult Time Unit,Conditions,Record ID,Condition 1a,Condition 1b,Condition 1c,Condition 2a,Condition 2b,Condition 2c,Condition 3,Condition 4,Condition 5 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,7,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − SNP response)/(maximum PE response − baseline before PE constriction)] × 100,,,98.24,%,0.82,2.1695,MMO:0000342,wire myography,mesenteric artery,0.0,BCA assay,,,,controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then sodium nitroprusside (0.316 umol/l) ,67673,controlled carbohydrate content diet (69 %) (for 91 days),controlled fat content diet (12 %) (for 91 days),controlled protein content diet (19 %) (for 91 days),phenylephrine (2 umol/l) ,,,sodium nitroprusside (0.316 umol/l) ,, 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,6,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,99.71,%,0.27,0.6614,MMO:0000342,wire myography,mesenteric artery,0.0,BCA assay,,,,controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (2 umol/l) then acetylcholine (3.16 umol/l) ,69616,controlled carbohydrate content diet (53 %) (for 91 days),controlled fat content diet (14 %) (for 91 days),controlled protein content diet (33 %) (for 91 days),phenylephrine (2 umol/l) ,,,acetylcholine (3.16 umol/l) ,, 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,10,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,99.53,%,0.41,1.2965,MMO:0000342,wire myography,mesenteric artery,0.0,,,,,controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then acetylcholine (3.16 umol/l) ,69617,controlled carbohydrate content diet (53 %) (for 63 days),controlled fat content diet (14 %) (for 63 days),controlled protein content diet (33 %) (for 63 days),controlled carbohydrate content diet (69 %) (for 28 days),controlled fat content diet (12 %) (for 28 days),controlled protein content diet (19 %) (for 28 days),phenylephrine (2 umol/l) ,acetylcholine (3.16 umol/l) , 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,6,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,100.24,%,0.28,0.6859,MMO:0000342,wire myography,mesenteric artery,0.0,,,,,controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then acetylcholine (3.16 umol/l) ,69618,controlled carbohydrate content diet (69 %) (for 91 days),controlled fat content diet (12 %) (for 91 days),controlled protein content diet (19 %) (for 91 days),phenylephrine (2 umol/l) ,,,acetylcholine (3.16 umol/l) ,, 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,6,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,100.14,%,0.37,0.9063,MMO:0000342,wire myography,mesenteric artery,0.0,,,,,controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then acetylcholine (3.16 umol/l) ,69619,controlled carbohydrate content diet (69 %) (for 63 days),controlled fat content diet (12 %) (for 63 days),controlled protein content diet (19 %) (for 63 days),controlled carbohydrate content diet (53 %) (for 28 days),controlled fat content diet (14 %) (for 28 days),controlled protein content diet (33 %) (for 28 days),phenylephrine (2 umol/l) ,acetylcholine (3.16 umol/l) , 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,5,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,94.99,%,0.39,0.8721,MMO:0000342,wire myography,mesenteric artery,0.0,BCA assay,,,,controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then acetylcholine (3.16 umol/l) ,69620,controlled carbohydrate content diet (53 %) (for 91 days),controlled fat content diet (14 %) (for 91 days),controlled protein content diet (33 %) (for 91 days),phenylephrine (2 umol/l) ,,,NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours),acetylcholine (3.16 umol/l) , 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,10,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,64.5,%,15.34,48.5093,MMO:0000342,wire myography,mesenteric artery,0.0,,,,,controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (3.16 umol/l) ,69621,controlled carbohydrate content diet (53 %) (for 63 days),controlled fat content diet (14 %) (for 63 days),controlled protein content diet (33 %) (for 63 days),controlled carbohydrate content diet (69 %) (for 28 days),controlled fat content diet (12 %) (for 28 days),controlled protein content diet (19 %) (for 28 days),phenylephrine (2 umol/l) ,NG-nitroarginine methyl ester (100 umol/l) ,acetylcholine (3.16 umol/l) 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,6,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,91.96,%,2.76,6.7606,MMO:0000342,wire myography,mesenteric artery,0.0,,,,,controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (3.16 umol/l) ,69622,controlled carbohydrate content diet (69 %) (for 91 days),controlled fat content diet (12 %) (for 91 days),controlled protein content diet (19 %) (for 91 days),phenylephrine (2 umol/l) ,,,NG-nitroarginine methyl ester (100 umol/l) ,acetylcholine (3.16 umol/l) , 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,6,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,92.95,%,1.46,3.5763,MMO:0000342,wire myography,mesenteric artery,0.0,,,,,controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (3.16 umol/l) ,69623,controlled carbohydrate content diet (69 %) (for 63 days),controlled fat content diet (12 %) (for 63 days),controlled protein content diet (19 %) (for 63 days),controlled carbohydrate content diet (53 %) (for 28 days),controlled fat content diet (14 %) (for 28 days),controlled protein content diet (33 %) (for 28 days),phenylephrine (2 umol/l) ,NG-nitroarginine methyl ester (100 umol/l) ,acetylcholine (3.16 umol/l) 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,4,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,70.84,%,4.18,8.36,MMO:0000342,wire myography,aorta,0.0,BCA assay,,,,controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (1 umol/l) then acetylcholine (31.6 umol/l) ,84652,controlled carbohydrate content diet (53 %) (for 91 days),controlled fat content diet (14 %) (for 91 days),controlled protein content diet (33 %) (for 91 days),phenylephrine (1 umol/l) ,,,acetylcholine (31.6 umol/l) ,, 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,7,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,73.42,%,5.62,14.8691,MMO:0000342,wire myography,aorta,0.0,,,,,controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (1 umol/l) then acetylcholine (31.6 umol/l) ,84653,controlled carbohydrate content diet (53 %) (for 63 days),controlled fat content diet (14 %) (for 63 days),controlled protein content diet (33 %) (for 63 days),controlled carbohydrate content diet (69 %) (for 28 days),controlled fat content diet (12 %) (for 28 days),controlled protein content diet (19 %) (for 28 days),phenylephrine (1 umol/l) ,acetylcholine (31.6 umol/l) , 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,4,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,80.04,%,2.63,5.26,MMO:0000342,wire myography,aorta,0.0,,,,,controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then acetylcholine (31.6 umol/l) ,84654,controlled carbohydrate content diet (69 %) (for 91 days),controlled fat content diet (12 %) (for 91 days),controlled protein content diet (19 %) (for 91 days),phenylephrine (1 umol/l) ,,,acetylcholine (31.6 umol/l) ,, 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,5,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,78.37,%,1.3,2.9069,MMO:0000342,wire myography,aorta,0.0,,,,,controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (1 umol/l) then acetylcholine (31.6 umol/l) ,84655,controlled carbohydrate content diet (69 %) (for 63 days),controlled fat content diet (12 %) (for 63 days),controlled protein content diet (19 %) (for 63 days),controlled carbohydrate content diet (53 %) (for 28 days),controlled fat content diet (14 %) (for 28 days),controlled protein content diet (33 %) (for 28 days),phenylephrine (1 umol/l) ,acetylcholine (31.6 umol/l) , 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,6,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,-19.03,%,4.01,9.8225,MMO:0000342,wire myography,aorta,0.0,BCA assay,,,,controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (1 umol/l) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then acetylcholine (31.6 umol/l) ,84656,controlled carbohydrate content diet (53 %) (for 91 days),controlled fat content diet (14 %) (for 91 days),controlled protein content diet (33 %) (for 91 days),phenylephrine (1 umol/l) ,,,NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours),acetylcholine (31.6 umol/l) , 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,10,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,-29.33,%,4.38,13.8508,MMO:0000342,wire myography,aorta,0.0,,,,,controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (1 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (31.6 umol/l) ,84657,controlled carbohydrate content diet (53 %) (for 63 days),controlled fat content diet (14 %) (for 63 days),controlled protein content diet (33 %) (for 63 days),controlled carbohydrate content diet (69 %) (for 28 days),controlled fat content diet (12 %) (for 28 days),controlled protein content diet (19 %) (for 28 days),phenylephrine (1 umol/l) ,NG-nitroarginine methyl ester (100 umol/l) ,acetylcholine (31.6 umol/l) 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,7,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,-12.94,%,4.38,11.5884,MMO:0000342,wire myography,aorta,0.0,,,,,controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (31.6 umol/l) ,84658,controlled carbohydrate content diet (69 %) (for 91 days),controlled fat content diet (12 %) (for 91 days),controlled protein content diet (19 %) (for 91 days),phenylephrine (1 umol/l) ,,,NG-nitroarginine methyl ester (100 umol/l) ,acetylcholine (31.6 umol/l) , 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,6,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − ACh response)/(maximum PE response − baseline before PE constriction)] × 100,,,-16.62,%,7.27,17.8078,MMO:0000342,wire myography,aorta,0.0,,,,,controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (1 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (31.6 umol/l) ,84659,controlled carbohydrate content diet (69 %) (for 63 days),controlled fat content diet (12 %) (for 63 days),controlled protein content diet (19 %) (for 63 days),controlled carbohydrate content diet (53 %) (for 28 days),controlled fat content diet (14 %) (for 28 days),controlled protein content diet (33 %) (for 28 days),phenylephrine (1 umol/l) ,NG-nitroarginine methyl ester (100 umol/l) ,acetylcholine (31.6 umol/l) 735,"Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26.",vasodilation trait,,RS:0002215,SS/HsdMcwiCrl,male,112 days,N/A,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,[(maximum PE response − SNP response)/(maximum PE response − baseline before PE constriction)] × 100,,,95.47,%,2.53,,MMO:0000342,wire myography,aorta,0.0,BCA assay,,,,controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then sodium nitroprusside (3.16 umol/l) ,84662,controlled carbohydrate content diet (69 %) (for 91 days),controlled fat content diet (12 %) (for 91 days),controlled protein content diet (19 %) (for 91 days),phenylephrine (1 umol/l) ,,,sodium nitroprusside (3.16 umol/l) ,,