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MITOGEN ACTIVATED PROTEIN KINASE SIGNALING PATHWAY (PW:0000007)

View Ontology Report

Description

The mitogen activated protein kinase pathways (MAPKs) represent highly conserved cascades activated in response to effectors downstream of receptor tyrosine kinases (RTKs) or in some cases G-protein coupled receptors (GPCRs), and in response to inflammatory cytokines and stress. Together, they control many cellular processes. The hallmark of MAPK pathways is the shared architecture of a three-tier signaling core: MAP3K/MAP2K/MAPK. The downstream tier and main effectors MAPKs are activated by pho

Pathway Diagram:

Ariadne Genomics Inc. Erk5 MAPK signaling pathway p38 MAPK signaling pathway c-Jun N-terminal kinases MAPK signaling pathway The extracellular signal-regulated RAF/MEK/ERK pathway immune response motility apoptosis proliferation differentiation survival cytokine receptors RTK Rho Ras Traf effectors2 adapters effectors1 inflammatory cytokines GF stress conditions
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Genes in Pathway:


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mitogen activated protein kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 IEA KEGG rno:04010 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEA KEGG rno:04010 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 IEA KEGG rno:04010 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Arrb1 arrestin, beta 1 IEA KEGG rno:04010 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Arrb2 arrestin, beta 2 IEA KEGG rno:04010 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Atf2 activating transcription factor 2 IEA KEGG rno:04010 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf4 activating transcription factor 4 IEA KEGG rno:04010 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Bdnf brain-derived neurotrophic factor IEA KEGG rno:04010 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA KEGG rno:04010 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B IEA KEGG rno:04010 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C IEA KEGG rno:04010 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IEA KEGG rno:04010 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E IEA KEGG rno:04010 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F IEA KEGG rno:04010 NCBI chr  X:14,868,096...14,896,413
Ensembl chr  X:14,868,024...14,896,413
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G IEA KEGG rno:04010 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IEA KEGG rno:04010 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I IEA KEGG rno:04010 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S IEA KEGG rno:04010 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IEA KEGG rno:04010 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 IEA KEGG rno:04010 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 IEA KEGG rno:04010 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351
JBrowse link
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 IEA KEGG rno:04010 NCBI chr 4:152,408,657...152,524,614
Ensembl chr 4:152,408,657...152,521,268
JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 IEA KEGG rno:04010 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 IEA KEGG rno:04010 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IEA KEGG rno:04010 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 IEA KEGG rno:04010 NCBI chr 3:36,906,771...37,169,191
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 IEA KEGG rno:04010 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 IEA KEGG rno:04010 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 IEA KEGG rno:04010 NCBI chr 1:177,201,990...177,296,473
Ensembl chr 1:177,201,288...177,297,024
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 IEA KEGG rno:04010 NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 IEA KEGG rno:04010 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614
JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 IEA KEGG rno:04010 NCBI chr 1:65,732,910...65,747,377
Ensembl chr 1:65,732,632...65,747,341
JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 IEA KEGG rno:04010 NCBI chr 1:65,800,820...65,831,165
Ensembl chr 1:65,800,355...65,831,006
JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 IEA KEGG rno:04010 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089
JBrowse link
G Casp3 caspase 3 IEA KEGG rno:04010 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccdc88b coiled-coil domain containing 88B IEA KEGG rno:04010 NCBI chr 1:204,036,913...204,052,878
Ensembl chr 1:204,036,918...204,052,970
JBrowse link
G Cd14 CD14 molecule IEA KEGG rno:04010 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cdc25b cell division cycle 25B IEA KEGG rno:04010 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc42 cell division cycle 42 IEA KEGG rno:04010 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 IEA KEGG rno:04010 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Chp2 calcineurin-like EF hand protein 2 IEA KEGG rno:04010 NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex IEA KEGG rno:04010 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Crk CRK proto-oncogene, adaptor protein IEA KEGG rno:04010 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein IEA KEGG rno:04010 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Daxx death-domain associated protein IEA KEGG rno:04010 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEA KEGG rno:04010 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dusp1 dual specificity phosphatase 1 IEA KEGG rno:04010 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 IEA KEGG rno:04010 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dusp14 dual specificity phosphatase 14 IEA KEGG rno:04010 NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
JBrowse link
G Dusp16 dual specificity phosphatase 16 IEA KEGG rno:04010 NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980
JBrowse link
G Dusp2 dual specificity phosphatase 2 IEA KEGG rno:04010 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
JBrowse link
G Dusp22 dual specificity phosphatase 22 IEA KEGG rno:04010 NCBI chr17:33,780,980...33,831,540
Ensembl chr17:33,780,981...33,831,321
JBrowse link
G Dusp3 dual specificity phosphatase 3 IEA KEGG rno:04010 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Dusp4 dual specificity phosphatase 4 IEA KEGG rno:04010 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp5 dual specificity phosphatase 5 IEA KEGG rno:04010 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp6 dual specificity phosphatase 6 IEA KEGG rno:04010 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dusp7 dual specificity phosphatase 7 IEA KEGG rno:04010 NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
JBrowse link
G Dusp8 dual specificity phosphatase 8 IEA KEGG rno:04010 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
JBrowse link
G Dusp9 dual specificity phosphatase 9 IEA KEGG rno:04010 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821
JBrowse link
G Ecsit ECSIT signaling integrator IEA KEGG rno:04010 NCBI chr 8:20,605,583...20,618,453
Ensembl chr 8:20,605,583...20,618,390
JBrowse link
G Egf epidermal growth factor IEA KEGG rno:04010 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor IEA KEGG rno:04010 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Elk1 ETS transcription factor ELK1 IEA KEGG rno:04010 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Elk4 ETS transcription factor ELK4 IEA KEGG rno:04010 NCBI chr13:43,451,130...43,475,035
Ensembl chr13:43,435,843...43,475,035
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IMP RGD PMID:16168116 RGD:1582137 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fas Fas cell surface death receptor IEA KEGG rno:04010 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand IEA KEGG rno:04010 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf1 fibroblast growth factor 1 IEA KEGG rno:04010 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf10 fibroblast growth factor 10 IEA KEGG rno:04010 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fgf11 fibroblast growth factor 11 IEA KEGG rno:04010 NCBI chr10:54,516,508...54,522,067
Ensembl chr10:54,517,077...54,522,062
JBrowse link
G Fgf12 fibroblast growth factor 12 IEA KEGG rno:04010 NCBI chr11:71,997,049...72,564,965
Ensembl chr11:71,997,099...72,562,607
JBrowse link
G Fgf13 fibroblast growth factor 13 IEA KEGG rno:04010 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Fgf14 fibroblast growth factor 14 IEA KEGG rno:04010 NCBI chr15:101,045,038...101,679,888
Ensembl chr15:101,045,036...101,679,900
JBrowse link
G Fgf16 fibroblast growth factor 16 IEA KEGG rno:04010 NCBI chr  X:70,816,658...70,827,270
Ensembl chr  X:70,817,433...70,878,717
JBrowse link
G Fgf17 fibroblast growth factor 17 IEA KEGG rno:04010 NCBI chr15:45,711,901...45,717,063
Ensembl chr15:45,711,998...45,717,063
JBrowse link
G Fgf18 fibroblast growth factor 18 IEA KEGG rno:04010 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Fgf19 fibroblast growth factor 19 IEA KEGG rno:04010 NCBI chr 1:200,056,656...200,059,944
Ensembl chr 1:200,056,644...200,060,287
JBrowse link
G Fgf2 fibroblast growth factor 2 IEA KEGG rno:04010 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf20 fibroblast growth factor 20 IEA KEGG rno:04010 NCBI chr16:52,030,853...52,037,612
Ensembl chr16:52,010,194...52,038,204
JBrowse link
G Fgf21 fibroblast growth factor 21 IEA KEGG rno:04010 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Fgf22 fibroblast growth factor 22 IEA KEGG rno:04010 NCBI chr 7:9,947,632...9,956,918
Ensembl chr 7:9,948,071...9,950,486
JBrowse link
G Fgf23 fibroblast growth factor 23 IEA KEGG rno:04010 NCBI chr 4:159,914,393...159,922,073
Ensembl chr 4:159,914,272...159,923,821
JBrowse link
G Fgf3 fibroblast growth factor 3 IEA KEGG rno:04010 NCBI chr 1:200,001,261...200,005,187
Ensembl chr 1:200,001,261...200,005,187
JBrowse link
G Fgf4 fibroblast growth factor 4 IEA KEGG rno:04010 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
JBrowse link
G Fgf5 fibroblast growth factor 5 IEA KEGG rno:04010 NCBI chr14:11,325,334...11,346,570
Ensembl chr14:11,325,334...11,345,997
JBrowse link
G Fgf6 fibroblast growth factor 6 IEA KEGG rno:04010 NCBI chr 4:159,854,913...159,863,447
Ensembl chr 4:159,854,913...159,863,447
JBrowse link
G Fgf7 fibroblast growth factor 7 IEA KEGG rno:04010 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
JBrowse link
G Fgf8 fibroblast growth factor 8 IEA KEGG rno:04010 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Fgf9 fibroblast growth factor 9 IEA KEGG rno:04010 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEA KEGG rno:04010 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IEA KEGG rno:04010 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 IEA KEGG rno:04010 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 IEA KEGG rno:04010 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Flna filamin A IEA KEGG rno:04010 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Flnb filamin B IEA KEGG rno:04010 NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
JBrowse link
G Flnc filamin C IEA KEGG rno:04010 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha IEA KEGG rno:04010 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta IEA KEGG rno:04010 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma IEA KEGG rno:04010 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gna12 G protein subunit alpha 12 IEA KEGG rno:04010 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255
JBrowse link
G Gng12 G protein subunit gamma 12 IEA KEGG rno:04010 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712
JBrowse link
G Grb2 growth factor receptor bound protein 2 IEA KEGG rno:04010 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Hras HRas proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A IEA KEGG rno:04010
G Hspa1b heat shock protein family A (Hsp70) member 1B IEA KEGG rno:04010 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like IEA KEGG rno:04010 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 IEA KEGG rno:04010 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEA KEGG rno:04010 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEA KEGG rno:04010 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IEA KEGG rno:04010 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma IEA KEGG rno:04010 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il1a interleukin 1 alpha IEA KEGG rno:04010 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta IEA KEGG rno:04010 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 IEA KEGG rno:04010 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il1r2 interleukin 1 receptor type 2 IEA KEGG rno:04010 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kras KRAS proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IEA KEGG rno:04010 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 IEA KEGG rno:04010 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IEA KEGG rno:04010 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IEA KEGG rno:04010 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 IEA KEGG rno:04010 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IEA KEGG rno:04010 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 IEA KEGG rno:04010 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IEA KEGG rno:04010 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 IEA KEGG rno:04010 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 IEA KEGG rno:04010 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 IEA KEGG rno:04010 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IEA KEGG rno:04010 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 IEA KEGG rno:04010 NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 IEA KEGG rno:04010 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 IEA KEGG rno:04010 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 IEA KEGG rno:04010 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358
JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 IEA KEGG rno:04010 NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 IEA KEGG rno:04010 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 IEA KEGG rno:04010 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 IEA KEGG rno:04010 NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493
JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 IEA KEGG rno:04010 NCBI chr 1:203,645,098...203,660,515
Ensembl chr 1:203,645,153...203,660,331
JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 IEA KEGG rno:04010 NCBI chr 6:14,276,623...14,446,321
Ensembl chr 6:14,277,121...14,446,334
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 IEA KEGG rno:04010 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEA KEGG rno:04010 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk10 mitogen activated protein kinase 10 IEA KEGG rno:04010 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IEA KEGG rno:04010 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 IEA KEGG rno:04010 NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664
JBrowse link
G Mapk13 mitogen activated protein kinase 13 IEA KEGG rno:04010 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222
JBrowse link
G Mapk14 mitogen activated protein kinase 14 IEA KEGG rno:04010 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEA KEGG rno:04010 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 IEA KEGG rno:04010 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEA KEGG rno:04010 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 IEA KEGG rno:04010 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 IEA KEGG rno:04010 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 IEA KEGG rno:04010 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA KEGG rno:04010 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 IEA KEGG rno:04010 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 IEA KEGG rno:04010 NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 IEA KEGG rno:04010 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052
JBrowse link
G Mapt microtubule-associated protein tau IEA KEGG rno:04010 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Max MYC associated factor X IEA KEGG rno:04010 NCBI chr 6:95,636,857...95,662,204
Ensembl chr 6:95,636,858...95,662,137
JBrowse link
G Mecom MDS1 and EVI1 complex locus IEA KEGG rno:04010 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Mef2c myocyte enhancer factor 2C IEA KEGG rno:04010 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 IEA KEGG rno:04010 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 IEA KEGG rno:04010 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mos MOS proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 5:16,859,957...16,861,264
Ensembl chr 5:16,859,957...16,861,264
JBrowse link
G Mras muscle RAS oncogene homolog IEA KEGG rno:04010 NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEA KEGG rno:04010 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nf1 neurofibromin 1 IEA KEGG rno:04010 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 IEA KEGG rno:04010 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 IEA KEGG rno:04010 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IEA KEGG rno:04010 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 IEA KEGG rno:04010 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Ngf nerve growth factor IEA KEGG rno:04010 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nlk nemo like kinase IEA KEGG rno:04010 NCBI chr10:63,467,163...63,590,960
Ensembl chr10:63,438,222...63,589,730
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 IEA KEGG rno:04010 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nras NRAS proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Ntf3 neurotrophin 3 IEA KEGG rno:04010 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Ntf4 neurotrophin 4 IEA KEGG rno:04010 NCBI chr 1:95,893,560...95,896,391
Ensembl chr 1:95,893,457...95,897,243
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEA KEGG rno:04010 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEA KEGG rno:04010 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 TAS
IEA
KEGG
RGD
PMID:9779826 rno:04010, RGD:70317 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 IEA KEGG rno:04010 NCBI chr11:68,708,070...68,766,622
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pdgfa platelet derived growth factor subunit A IEA KEGG rno:04010 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEA KEGG rno:04010 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEA KEGG rno:04010 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEA KEGG rno:04010 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pla2g10 phospholipase A2, group X IEA KEGG rno:04010 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000
JBrowse link
G Pla2g12a phospholipase A2, group XIIA IEA KEGG rno:04010 NCBI chr 2:218,436,450...218,452,760
Ensembl chr 2:218,436,513...218,452,740
JBrowse link
G Pla2g12b phospholipase A2, group XIIB IEA KEGG rno:04010 NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743
JBrowse link
G Pla2g1b phospholipase A2 group IB IEA KEGG rno:04010 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
JBrowse link
G Pla2g2a phospholipase A2 group IIA IEA KEGG rno:04010 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Pla2g2c phospholipase A2, group IIC IEA KEGG rno:04010 NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377
JBrowse link
G Pla2g2d phospholipase A2, group IID IEA KEGG rno:04010 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525
JBrowse link
G Pla2g2f phospholipase A2, group IIF IEA KEGG rno:04010 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175
JBrowse link
G Pla2g3 phospholipase A2, group III IEA KEGG rno:04010 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEA KEGG rno:04010 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g4b phospholipase A2 group IVB IEA KEGG rno:04010 NCBI chr 3:107,004,238...107,013,853
Ensembl chr 3:107,005,489...107,013,853
JBrowse link
G Pla2g4e phospholipase A2, group IVE IEA KEGG rno:04010 NCBI chr 3:107,132,540...107,198,609
Ensembl chr 3:107,132,541...107,198,233
JBrowse link
G Pla2g4f phospholipase A2, group IVF IEA KEGG rno:04010 NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689
JBrowse link
G Pla2g5 phospholipase A2, group V IEA KEGG rno:04010 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Pla2g6 phospholipase A2 group VI IEA KEGG rno:04010 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A IEA KEGG rno:04010 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B IEA KEGG rno:04010 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IEA KEGG rno:04010 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IEA KEGG rno:04010 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma IEA KEGG rno:04010 NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha IEA KEGG rno:04010 NCBI chr14:91,556,743...91,606,230
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta IEA KEGG rno:04010 NCBI chr 5:64,026,903...64,027,898
Ensembl chr 5:64,026,903...64,032,548
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit IEA KEGG rno:04010 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEA KEGG rno:04010 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta IEA KEGG rno:04010 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prkca protein kinase C, alpha IEA KEGG rno:04010 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcb protein kinase C, beta IEA KEGG rno:04010 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcg protein kinase C, gamma IEA KEGG rno:04010 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Prkx protein kinase, X-linked IEA KEGG rno:04010 NCBI chr  X:41,823,349...41,866,844
Ensembl chr  X:41,823,355...41,866,669
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IEA KEGG rno:04010 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Ptpn7 protein tyrosine phosphatase, non-receptor type 7 IEA KEGG rno:04010 NCBI chr13:46,570,904...46,584,048
Ensembl chr13:46,571,712...46,583,308
JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R IEA KEGG rno:04010 NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603
JBrowse link
G Rac1 Rac family small GTPase 1 IEA KEGG rno:04010 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rac2 Rac family small GTPase 2 IEA KEGG rno:04010 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IEA KEGG rno:04010 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family IEA KEGG rno:04010 NCBI chr 7:53,423,039...53,456,388
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 IEA KEGG rno:04010 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
JBrowse link
G Rasa1 RAS p21 protein activator 1 IEA KEGG rno:04010 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Rasa2 RAS p21 protein activator 2 IEA KEGG rno:04010 NCBI chr 8:97,119,983...97,236,687
Ensembl chr 8:97,118,802...97,236,671
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEA KEGG rno:04010 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
JBrowse link
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 IEA KEGG rno:04010 NCBI chr 2:23,113,613...23,361,537 JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA KEGG rno:04010 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 IEA KEGG rno:04010 NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993
JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 IEA KEGG rno:04010 NCBI chr 6:19,895,366...19,993,945
Ensembl chr 6:19,895,390...19,958,578
JBrowse link
G Rasgrp4 RAS guanyl releasing protein 4 IEA KEGG rno:04010 NCBI chr 1:84,433,033...84,452,841
Ensembl chr 1:84,433,064...84,451,896
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEA KEGG rno:04010 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RGD1564956 similar to calcium binding protein P22 IEA KEGG rno:04010 NCBI chr 5:68,570,894...68,571,875 JBrowse link
G RGD1565395 similar to stathmin 1/oncoprotein 18) IEA KEGG rno:04010 NCBI chr10:80,274,041...80,274,523
Ensembl chr10:80,274,041...80,274,496
JBrowse link
G RGD1565588 similar to calcium binding protein P22 IEA KEGG rno:04010
G Rps6ka1 ribosomal protein S6 kinase A1 IEA KEGG rno:04010 NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 IEA KEGG rno:04010 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 IEA KEGG rno:04010 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 IEA KEGG rno:04010 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 IEA KEGG rno:04010 NCBI chr  X:76,354,824...76,454,484
Ensembl chr  X:76,353,760...76,454,484
JBrowse link
G Rras RAS related IEA KEGG rno:04010 NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357
JBrowse link
G Rras2 RAS related 2 IEA KEGG rno:04010 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
JBrowse link
G Shc1 SHC adaptor protein 1 IDA RGD PMID:12837289 RGD:1304398 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IEA KEGG rno:04010 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 IEA KEGG rno:04010 NCBI chr 6:88,042,966...88,156,140
Ensembl chr 6:88,042,966...88,156,692
JBrowse link
G Srf serum response factor IEA KEGG rno:04010 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Stk3 serine/threonine kinase 3 IEA KEGG rno:04010 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233
JBrowse link
G Stk4 serine/threonine kinase 4 IEA KEGG rno:04010 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link
G Stmn1 stathmin 1 IEA KEGG rno:04010 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Taok1 TAO kinase 1 IEA KEGG rno:04010 NCBI chr10:62,373,076...62,465,295
Ensembl chr10:62,381,404...62,465,766
JBrowse link
G Taok2 TAO kinase 2 IEA KEGG rno:04010 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613
JBrowse link
G Taok3 TAO kinase 3 IEA KEGG rno:04010 NCBI chr12:39,314,027...39,394,243
Ensembl chr12:39,314,027...39,461,244
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEA KEGG rno:04010 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEA KEGG rno:04010 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IEA KEGG rno:04010 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IEA KEGG rno:04010 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEA KEGG rno:04010 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tnf tumor necrosis factor IEA KEGG rno:04010 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEA KEGG rno:04010 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tp53 tumor protein p53 IEA KEGG rno:04010 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Traf2 Tnf receptor-associated factor 2 IEA KEGG rno:04010 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Traf6 TNF receptor associated factor 6 IEA KEGG rno:04010 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:14612383 RGD:1580517 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link
altered Erk5 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k5 mitogen activated protein kinase kinase 5 ISO RGD PMID:16376520 RGD:2298532 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO RGD PMID:16376520 RGD:2298532 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
altered extracellular signal-regulated Raf/Mek/Erk signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO RGD PMID:17126425 PMID:21277552 PMID:20951313 PMID:18098337 RGD:2293882, RGD:5133243, RGD:5133242, RGD:2298531 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Kras KRAS proto-oncogene, GTPase TAS
ISO
RGD PMID:16112461 PMID:18772397 PMID:19506583 PMID:20951313 PMID:19078924 RGD:2306732, RGD:5490966, RGD:5490965, RGD:5133242, RGD:4143515 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO RGD PMID:20951313 PMID:21277552 RGD:5133242, RGD:5133243 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO RGD PMID:17126425 RGD:2293882 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
c-Jun N-terminal kinases MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 ISO RGD PMID:8910292 PMID:9305638 RGD:2293876, RGD:2293879 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO RGD PMID:17208316 RGD:2293881 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 ISO RGD PMID:17208316 RGD:2293881 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dusp16 dual specificity phosphatase 16 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980
JBrowse link
G Dusp19 dual specificity phosphatase 19 ISO RGD PMID:11959862 RGD:2314491 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534
JBrowse link
G Dusp8 dual specificity phosphatase 8 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO
IDA
RGD PMID:17306896 PMID:12524169 PMID:17064355 PMID:10051439 RGD:2293875, RGD:2298708, RGD:2298577, RGD:2298561 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO
IDA
RGD PMID:17306896 PMID:17064355 PMID:15680699 PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298567, RGD:2298561 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 1:82,955,783...82,974,084
Ensembl chr 1:82,955,207...82,974,084
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO
IDA
RGD PMID:8910292 PMID:17064355 PMID:15680699 PMID:17306896 RGD:2293876, RGD:2298577, RGD:2298567, RGD:2293875 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 ISO RGD PMID:17306896 RGD:2293875 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Map3k21 mitogen-activated protein kinase kinase kinase 21 ISO RGD PMID:17306896 RGD:2293875 NCBI chr19:53,880,032...53,913,560
Ensembl chr19:53,880,238...53,913,576
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:12215209 PMID:17306896 RGD:2293875 RGD:2296020 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Map3k9 mitogen-activated protein kinase kinase kinase 9 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 6:101,423,754...101,488,822
Ensembl chr 6:101,430,292...101,488,822
JBrowse link
G Mapk10 mitogen activated protein kinase 10 ISO
IDA
RGD PMID:17306896 PMID:15680699 PMID:10051439 RGD:2293875, RGD:2298567, RGD:2298561 NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO
IDA
RGD PMID:17306896 PMID:17064355 PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298561 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 ISO
IDA
RGD PMID:17726577 PMID:15816852 RGD:2293880, RGD:1579811 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 ISO RGD PMID:17726577 RGD:2293880 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 ISO RGD PMID:17726577 RGD:2293880 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO
IDA
RGD PMID:17306896 PMID:17064355 PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298561 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Rac1 Rac family small GTPase 1 ISO RGD PMID:8910292 PMID:9305638 RGD:2293876, RGD:2293879 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:10811109 RGD:11534984 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15757900 RGD:1581337 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO RGD PMID:12215209 RGD:2296020 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
Erk5 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k5 mitogen activated protein kinase kinase 5 ISO
IMP
RGD PMID:16376520 PMID:15631999 RGD:2298532, RGD:1582263 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 ISO RGD PMID:16376520 RGD:2298532 NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO RGD PMID:16376520 RGD:2298532 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO
IMP
RGD PMID:16376520 PMID:11782488 RGD:2298532, RGD:2298794 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Sh2d2a SH2 domain containing 2A ISO RGD PMID:16376520 RGD:2298532 NCBI chr 2:173,312,253...173,318,810
Ensembl chr 2:173,312,253...173,318,810
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 ISO RGD PMID:16376520 RGD:2298532 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
JBrowse link
p38 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin IMP RGD PMID:16157033 RGD:1625329 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Atm ATM serine/threonine kinase ISO PID PID:200018 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Bnip2 BCL2 interacting protein 2 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590
JBrowse link
G Calm1 calmodulin 1 ISO PID PID:200018 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 ISO PID PID:200018 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
JBrowse link
G Calm3 calmodulin 3 ISO PID PID:200018 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO PID PID:200018 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Ccm2 CCM2 scaffold protein ISO PID
RGD
PMID:17481747 PMID:20626350 PID:200018, RGD:2293891, RGD:7240533 NCBI chr14:81,418,418...81,464,114
Ensembl chr14:81,418,236...81,464,116
JBrowse link
G Cdc42 cell division cycle 42 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdon cell adhesion associated, oncogene regulated ISO RGD PMID:20626350 RGD:7240533 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 ISO RGD PMID:20626350 RGD:7240533 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dusp16 dual specificity phosphatase 16 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980
JBrowse link
G Dusp9 dual specificity phosphatase 9 ISO RGD PMID:20626350 RGD:7240533 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO PID PID:200018 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta ISO PID PID:200018 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma ISO PID PID:200018 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:15141302 RGD:5128786 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 ISO
IDA
PID
RGD
PMID:17481747 PMID:16183734 PID:200018, RGD:2293891, RGD:2298758 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO
IDA
PID
RGD
PMID:17481747 PMID:16183734 PID:200018, RGD:2293891, RGD:2298758 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200018 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 ISO PID PID:200018 NCBI chr 1:82,955,783...82,974,084
Ensembl chr 1:82,955,207...82,974,084
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO PID
RGD
PMID:17481747 PMID:20626350 PID:200018, RGD:2293891, RGD:7240533 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO PID
RGD
PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO PID
RGD
PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 ISO PID PID:200018 NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO
IDA
PID
RGD
PMID:17481747 PMID:20626350 PMID:16183734 PID:200018, RGD:2293891, RGD:7240533, RGD:2298758 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ISO RGD PMID:20626350 RGD:7240533 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO PID
RGD
PMID:17481747 PID:200018, RGD:2293891 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 ISO RGD PMID:17481747 RGD:2293891 NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664
JBrowse link
G Mapk13 mitogen activated protein kinase 13 ISO RGD PMID:17481747 RGD:2293891 NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222
JBrowse link
G Mapk14 mitogen activated protein kinase 14 IDA
ISO
PID
RGD
PMID:16407200 PMID:17481747 PID:200018, RGD:1580544, RGD:2293891 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 ISO
IMP
RGD PMID:17481747 PMID:12024021 RGD:2293891, RGD:2302280 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G Rac1 Rac family small GTPase 1 ISO PID
RGD
PMID:17481747 PID:200018, RGD:2293891 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:204,021,805...204,032,781
Ensembl chr 1:204,021,806...204,032,761
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
JBrowse link
G Spag9 sperm associated antigen 9 ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797
JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 ISO PID PID:200018 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058
JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO PID PID:200018 NCBI chr 1:2,375,026...2,424,759
Ensembl chr 1:2,375,490...2,424,756
JBrowse link
G Taok1 TAO kinase 1 ISO PID
RGD
PMID:20626350 PID:200018, RGD:7240533 NCBI chr10:62,373,076...62,465,295
Ensembl chr10:62,381,404...62,465,766
JBrowse link
G Taok2 TAO kinase 2 ISO PID
RGD
PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613
JBrowse link
G Taok3 TAO kinase 3 ISO PID PID:200018 NCBI chr12:39,314,027...39,394,243
Ensembl chr12:39,314,027...39,461,244
JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO PID
RGD
PMID:12215209 PID:200018, RGD:2296020 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO PID
RGD
PMID:20626350 PID:200018, RGD:7240533 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Txn1 thioredoxin 1 ISO PID PID:200018 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
the extracellular signal-regulated Raf/Mek/Erk signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase ISO RGD PMID:22177953 RGD:5686410 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase IMP
ISO
RGD PMID:16508002 PMID:22177953 PMID:17310240 RGD:1580106, RGD:5686410, RGD:1626216 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Dusp6 dual specificity phosphatase 6 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:20445128 RGD:4892084 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO RGD PMID:22177953 RGD:5686410 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Kras KRAS proto-oncogene, GTPase IDA
ISO
RGD PMID:12388314 PMID:22177953 RGD:628557, RGD:5686410 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Ksr1 kinase suppressor of ras 1 ISO RGD PMID:17726577 PMID:22177953 RGD:2293880, RGD:5686410 NCBI chr10:63,961,771...64,098,076
Ensembl chr10:63,961,759...64,098,076
JBrowse link
G Ksr2 kinase suppressor of ras 2 ISO RGD PMID:22177953 RGD:5686410 NCBI chr12:38,802,796...39,187,809
Ensembl chr12:38,802,004...39,188,375
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 TAS
IMP
RGD PMID:9779826 PMID:17310240 RGD:70317, RGD:1626216 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 NAS
IMP
RGD PMID:8462694 PMID:17310240 RGD:729046, RGD:1626216 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISS
ISO
RGD PMID:12835716 PMID:9305638 RGD:1357969, RGD:2293879 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 NAS RGD PMID:11359865 RGD:724475 NCBI chr18:23,807,218...23,879,722
Ensembl chr18:23,807,218...23,871,433
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA
IMP
RGD PMID:12097495 PMID:16955078 PMID:17310240 RGD:628468, RGD:8553011, RGD:1626216 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA
ISO
IMP
RGD PMID:12097495 PMID:20080775 PMID:16955078 PMID:17310240 RGD:628468, RGD:5508172, RGD:8553011, RGD:1626216 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO
IMP
RGD PMID:16421520 PMID:16955078 RGD:2315047, RGD:8553011 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO RGD PMID:22177953 RGD:5686410 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 TAS
IMP
RGD PMID:17126425 PMID:10490027 RGD:2293882, RGD:2302807 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Prkcd protein kinase C, delta IMP RGD PMID:12790799 RGD:1642529 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15096502 RGD:1642630 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase TAS
ISO
IMP
RGD PMID:9779826 PMID:22177953 PMID:17310240 PMID:16508002 RGD:70317, RGD:5686410, RGD:1626216, RGD:1580106 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 ISO RGD PMID:16421520 RGD:2315047 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207
JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:204,021,805...204,032,781
Ensembl chr 1:204,021,806...204,032,761
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 ISO RGD PMID:16421520 RGD:2315047 NCBI chr  X:76,354,824...76,454,484
Ensembl chr  X:76,353,760...76,454,484
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IMP RGD PMID:14711826 RGD:1304283 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Shc1 SHC adaptor protein 1 IEP RGD PMID:16699171 RGD:1643182 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
JBrowse link
G Smad1 SMAD family member 1 IMP RGD PMID:16427075 RGD:1643230 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15757900 RGD:1581337 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tsc2 TSC complex subunit 2 ISO RGD PMID:15150271 RGD:1580097 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
JBrowse link

Pathway Gene Annotations

Disease Annotations Associated with Genes in the mitogen activated protein kinase signaling pathway