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MITOGEN ACTIVATED PROTEIN KINASE SIGNALING PATHWAY (PW:0000007)

View Ontology Report

Description

The mitogen activated protein kinase pathways (MAPKs) represent highly conserved cascades activated in response to effectors downstream of receptor tyrosine kinases (RTKs) or in some cases G-protein coupled receptors (GPCRs), and in response to inflammatory cytokines and stress. Together, they control many cellular processes. The hallmark of MAPK pathways is the shared architecture of a three-tier signaling core: MAP3K/MAP2K/MAPK. The downstream tier and main effectors MAPKs are activated by pho

Pathway Diagram:

Ariadne Genomics Inc. Erk5 MAPK signaling pathway p38 MAPK signaling pathway c-Jun N-terminal kinases MAPK signaling pathway The extracellular signal-regulated RAF/MEK/ERK pathway immune response motility apoptosis proliferation differentiation survival cytokine receptors RTK Rho Ras Traf effectors2 adapters effectors1 inflammatory cytokines GF stress conditions
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Genes in Pathway:

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mitogen activated protein kinase signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 IEA KEGG rno:04010 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEA KEGG rno:04010 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Akt3 AKT serine/threonine kinase 3 IEA KEGG rno:04010 NCBI chr13:95,076,308...95,348,913
Ensembl chr13:95,081,390...95,348,913
JBrowse link
G Arrb1 arrestin, beta 1 IEA KEGG rno:04010 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Arrb2 arrestin, beta 2 IEA KEGG rno:04010 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atf2 activating transcription factor 2 IEA KEGG rno:04010 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf4 activating transcription factor 4 IEA KEGG rno:04010 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Bdnf brain-derived neurotrophic factor IEA KEGG rno:04010 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA KEGG rno:04010 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B IEA KEGG rno:04010 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C IEA KEGG rno:04010 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IEA KEGG rno:04010 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E IEA KEGG rno:04010 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F IEA KEGG rno:04010 NCBI chr  X:15,712,709...15,741,135
Ensembl chr  X:15,712,713...15,741,103
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G IEA KEGG rno:04010 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IEA KEGG rno:04010 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I IEA KEGG rno:04010 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S IEA KEGG rno:04010 NCBI chr13:52,889,570...52,964,558
Ensembl chr13:52,889,737...52,964,155
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IEA KEGG rno:04010 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 IEA KEGG rno:04010 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985
JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 IEA KEGG rno:04010 NCBI chr16:4,871,348...5,795,825
Ensembl chr16:4,871,650...5,795,825
JBrowse link
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 IEA KEGG rno:04010 NCBI chr 4:151,298,548...151,409,263
Ensembl chr 4:151,298,548...151,409,263
JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 IEA KEGG rno:04010 NCBI chr10:85,954,138...85,974,764
Ensembl chr10:85,954,138...85,974,651
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 IEA KEGG rno:04010 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IEA KEGG rno:04010 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 IEA KEGG rno:04010 NCBI chr 3:37,950,846...38,211,478
Ensembl chr 3:37,955,069...38,090,526
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 IEA KEGG rno:04010 NCBI chr10:95,921,479...95,934,170
Ensembl chr10:95,921,174...95,934,345
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 IEA KEGG rno:04010 NCBI chr 7:119,228,112...119,353,332
Ensembl chr 7:119,228,102...119,352,605
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 IEA KEGG rno:04010 NCBI chr 1:192,613,766...192,708,371
Ensembl chr 1:192,613,372...192,709,078
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 IEA KEGG rno:04010 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 IEA KEGG rno:04010 NCBI chr10:96,122,240...96,166,606
Ensembl chr10:96,123,397...96,131,880
JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 IEA KEGG rno:04010 NCBI chr 1:64,307,684...64,322,124
Ensembl chr 1:64,305,438...64,321,241
JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 IEA KEGG rno:04010 NCBI chr 1:64,374,547...64,405,380
Ensembl chr 1:64,374,603...64,405,149
JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 IEA KEGG rno:04010 NCBI chr 1:64,330,106...64,350,338
Ensembl chr 1:64,330,106...64,350,338
JBrowse link
G Casp3 caspase 3 IEA KEGG rno:04010 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccdc88b coiled-coil domain containing 88B IEA KEGG rno:04010 NCBI chr 1:222,102,436...222,118,485
Ensembl chr 1:222,102,437...222,118,459
JBrowse link
G Cd14 CD14 molecule IEA KEGG rno:04010 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cdc25b cell division cycle 25B IEA KEGG rno:04010 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdc42 cell division cycle 42 IEA KEGG rno:04010 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 IEA KEGG rno:04010 NCBI chr 3:111,354,506...111,389,998
Ensembl chr 3:111,354,506...111,389,989
JBrowse link
G Chp2 calcineurin-like EF hand protein 2 IEA KEGG rno:04010 NCBI chr 1:192,169,634...192,173,228
Ensembl chr 1:192,169,841...192,173,253
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex IEA KEGG rno:04010 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Crk CRK proto-oncogene, adaptor protein IEA KEGG rno:04010 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein IEA KEGG rno:04010 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043
JBrowse link
G Daxx death-domain associated protein IEA KEGG rno:04010 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEA KEGG rno:04010 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dusp1 dual specificity phosphatase 1 IEA KEGG rno:04010 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp10 dual specificity phosphatase 10 IEA KEGG rno:04010 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dusp14 dual specificity phosphatase 14 IEA KEGG rno:04010 NCBI chr10:71,363,688...71,383,602
Ensembl chr10:71,363,688...71,383,602
JBrowse link
G Dusp16 dual specificity phosphatase 16 IEA KEGG rno:04010 NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
JBrowse link
G Dusp2 dual specificity phosphatase 2 IEA KEGG rno:04010 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G Dusp22 dual specificity phosphatase 22 IEA KEGG rno:04010 NCBI chr17:34,986,589...35,037,297
Ensembl chr17:34,986,591...35,037,076
JBrowse link
G Dusp3 dual specificity phosphatase 3 IEA KEGG rno:04010 NCBI chr10:89,904,578...89,918,296
Ensembl chr10:89,904,560...89,918,427
JBrowse link
G Dusp4 dual specificity phosphatase 4 IEA KEGG rno:04010 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G Dusp5 dual specificity phosphatase 5 IEA KEGG rno:04010 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp6 dual specificity phosphatase 6 IEA KEGG rno:04010 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dusp7 dual specificity phosphatase 7 IEA KEGG rno:04010 NCBI chr 8:115,069,095...115,076,130
Ensembl chr 8:115,069,095...115,076,130
JBrowse link
G Dusp8 dual specificity phosphatase 8 IEA KEGG rno:04010 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460
JBrowse link
G Dusp9 dual specificity phosphatase 9 IEA KEGG rno:04010 NCBI chr  X:157,168,143...157,172,068
Ensembl chr  X:157,168,144...157,172,068
JBrowse link
G Ecsit ECSIT signaling integrator IEA KEGG rno:04010 NCBI chr 8:23,085,598...23,099,064
Ensembl chr 8:23,085,590...23,099,042
JBrowse link
G Egf epidermal growth factor IEA KEGG rno:04010 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor IEA KEGG rno:04010 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Elk1 ETS transcription factor ELK1 IEA KEGG rno:04010 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Elk4 ETS transcription factor ELK4 IEA KEGG rno:04010 NCBI chr13:48,788,262...48,813,267
Ensembl chr13:48,790,509...48,813,260
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IMP RGD PMID:16168116 RGD:1582137 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Fas Fas cell surface death receptor IEA KEGG rno:04010 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand IEA KEGG rno:04010 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf1 fibroblast growth factor 1 IEA KEGG rno:04010 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf10 fibroblast growth factor 10 IEA KEGG rno:04010 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgf11 fibroblast growth factor 11 IEA KEGG rno:04010 NCBI chr10:56,403,320...56,410,816
Ensembl chr10:56,403,256...56,409,017
JBrowse link
G Fgf12 fibroblast growth factor 12 IEA KEGG rno:04010 NCBI chr11:75,606,360...76,171,078
Ensembl chr11:75,905,443...76,168,989
JBrowse link
G Fgf13 fibroblast growth factor 13 IEA KEGG rno:04010 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Fgf14 fibroblast growth factor 14 IEA KEGG rno:04010 NCBI chr15:110,382,274...111,077,027
Ensembl chr15:110,385,217...110,612,681
JBrowse link
G Fgf16 fibroblast growth factor 16 IEA KEGG rno:04010 NCBI chr  X:76,786,728...76,796,311
Ensembl chr  X:76,786,466...76,797,069
JBrowse link
G Fgf17 fibroblast growth factor 17 IEA KEGG rno:04010 NCBI chr15:52,326,758...52,337,360
Ensembl chr15:52,326,778...52,332,097
JBrowse link
G Fgf18 fibroblast growth factor 18 IEA KEGG rno:04010 NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391
JBrowse link
G Fgf19 fibroblast growth factor 19 IEA KEGG rno:04010 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G Fgf2 fibroblast growth factor 2 IEA KEGG rno:04010 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf20 fibroblast growth factor 20 IEA KEGG rno:04010 NCBI chr16:55,152,748...55,159,352
Ensembl chr16:55,152,748...55,159,352
JBrowse link
G Fgf21 fibroblast growth factor 21 IEA KEGG rno:04010 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fgf22 fibroblast growth factor 22 IEA KEGG rno:04010 NCBI chr 7:12,829,785...12,831,675
Ensembl chr 7:12,829,785...12,831,675
JBrowse link
G Fgf23 fibroblast growth factor 23 IEA KEGG rno:04010 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Fgf3 fibroblast growth factor 3 IEA KEGG rno:04010 NCBI chr 1:218,003,018...218,006,942
Ensembl chr 1:218,003,018...218,006,942
JBrowse link
G Fgf4 fibroblast growth factor 4 IEA KEGG rno:04010 NCBI chr 1:218,024,537...218,029,539
Ensembl chr 1:218,025,810...218,027,220
JBrowse link
G Fgf5 fibroblast growth factor 5 IEA KEGG rno:04010 NCBI chr14:12,974,921...12,996,046
Ensembl chr14:12,974,921...12,995,584
JBrowse link
G Fgf6 fibroblast growth factor 6 IEA KEGG rno:04010 NCBI chr 4:159,563,798...159,572,333
Ensembl chr 4:159,563,798...159,572,333
JBrowse link
G Fgf7 fibroblast growth factor 7 IEA KEGG rno:04010 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Fgf8 fibroblast growth factor 8 IEA KEGG rno:04010 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Fgf9 fibroblast growth factor 9 IEA KEGG rno:04010 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEA KEGG rno:04010 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IEA KEGG rno:04010 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 IEA KEGG rno:04010 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 IEA KEGG rno:04010 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321
JBrowse link
G Flna filamin A IEA KEGG rno:04010 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Flnb filamin B IEA KEGG rno:04010 NCBI chr15:18,750,152...18,883,019
Ensembl chr15:18,750,118...18,883,005
JBrowse link
G Flnc filamin C IEA KEGG rno:04010 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha IEA KEGG rno:04010 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta IEA KEGG rno:04010 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma IEA KEGG rno:04010 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gna12 G protein subunit alpha 12 IEA KEGG rno:04010 NCBI chr12:15,890,202...15,971,212
Ensembl chr12:15,890,170...15,971,212
JBrowse link
G Gng12 G protein subunit gamma 12 IEA KEGG rno:04010 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Grb2 growth factor receptor bound protein 2 IEA KEGG rno:04010 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Hras HRas proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A IEA KEGG rno:04010 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IEA KEGG rno:04010 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like IEA KEGG rno:04010 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 IEA KEGG rno:04010 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEA KEGG rno:04010 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEA KEGG rno:04010 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta IEA KEGG rno:04010 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma IEA KEGG rno:04010 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il1a interleukin 1 alpha IEA KEGG rno:04010 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta IEA KEGG rno:04010 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 IEA KEGG rno:04010 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il1r2 interleukin 1 receptor type 2 IEA KEGG rno:04010 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit IEA KEGG rno:04010 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kras KRAS proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IEA KEGG rno:04010 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 IEA KEGG rno:04010 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IEA KEGG rno:04010 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IEA KEGG rno:04010 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 IEA KEGG rno:04010 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IEA KEGG rno:04010 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 IEA KEGG rno:04010 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IEA KEGG rno:04010 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 IEA KEGG rno:04010 NCBI chr 1:221,043,119...221,056,420
Ensembl chr 1:221,043,119...221,056,417
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 IEA KEGG rno:04010 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 IEA KEGG rno:04010 NCBI chr11:82,744,391...82,938,357
Ensembl chr11:82,745,735...82,938,357
JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 IEA KEGG rno:04010 NCBI chr10:91,303,428...91,353,601
Ensembl chr10:91,303,428...91,353,601
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 IEA KEGG rno:04010 NCBI chr18:24,961,250...25,025,488
Ensembl chr18:24,961,245...25,025,897
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 IEA KEGG rno:04010 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 IEA KEGG rno:04010 NCBI chr10:94,280,703...94,349,372
Ensembl chr10:94,280,703...94,349,368
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 IEA KEGG rno:04010 NCBI chr 1:48,625,714...48,711,642
Ensembl chr 1:48,625,743...48,711,642
JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 IEA KEGG rno:04010 NCBI chr 5:151,435,679...151,448,329
Ensembl chr 5:151,436,464...151,448,328
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 IEA KEGG rno:04010 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 IEA KEGG rno:04010 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 IEA KEGG rno:04010 NCBI chr 1:87,937,126...87,959,514
Ensembl chr 1:87,938,042...87,959,569
JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 IEA KEGG rno:04010 NCBI chr 1:221,710,622...221,726,274
Ensembl chr 1:221,710,670...221,725,656
JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 IEA KEGG rno:04010 NCBI chr 6:3,276,732...3,444,519
Ensembl chr 6:3,276,738...3,444,519
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 IEA KEGG rno:04010 NCBI chr 9:46,657,444...46,782,545
Ensembl chr 9:46,657,575...46,782,545
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEA KEGG rno:04010 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk10 mitogen activated protein kinase 10 IEA KEGG rno:04010 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 IEA KEGG rno:04010 NCBI chr 7:130,121,678...130,129,199
Ensembl chr 7:130,121,687...130,128,604
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 IEA KEGG rno:04010 NCBI chr 7:130,109,214...130,120,918
Ensembl chr 7:130,109,663...130,120,579
JBrowse link
G Mapk13 mitogen activated protein kinase 13 IEA KEGG rno:04010 NCBI chr20:6,018,374...6,027,467
Ensembl chr20:6,018,374...6,027,473
JBrowse link
G Mapk14 mitogen activated protein kinase 14 IEA KEGG rno:04010 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEA KEGG rno:04010 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 IEA KEGG rno:04010 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEA KEGG rno:04010 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 IEA KEGG rno:04010 NCBI chr 3:81,295,023...81,304,181
Ensembl chr 3:81,295,024...81,304,181
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 IEA KEGG rno:04010 NCBI chr 7:130,430,588...130,440,838
Ensembl chr 7:130,431,213...130,440,703
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 IEA KEGG rno:04010 NCBI chr10:14,259,394...14,299,276
Ensembl chr10:14,260,787...14,299,167
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA KEGG rno:04010 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 IEA KEGG rno:04010 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 IEA KEGG rno:04010 NCBI chr 8:116,012,126...116,046,012
Ensembl chr 8:116,012,121...116,045,954
JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 IEA KEGG rno:04010 NCBI chr12:40,510,378...40,529,332
Ensembl chr12:40,510,378...40,529,338
JBrowse link
G Mapt microtubule-associated protein tau IEA KEGG rno:04010 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Max MYC associated factor X IEA KEGG rno:04010 NCBI chr 6:99,984,260...100,011,460
Ensembl chr 6:99,984,260...100,011,388
JBrowse link
G Mecom MDS1 and EVI1 complex locus IEA KEGG rno:04010 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769
JBrowse link
G Mef2c myocyte enhancer factor 2C IEA KEGG rno:04010 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 IEA KEGG rno:04010 NCBI chr 5:134,691,852...134,730,887
Ensembl chr 5:134,691,881...134,730,893
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 IEA KEGG rno:04010 NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
JBrowse link
G Mos MOS proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 5:16,746,085...16,747,392
Ensembl chr 5:16,746,197...16,747,222
JBrowse link
G Mras muscle RAS oncogene homolog IEA KEGG rno:04010 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEA KEGG rno:04010 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nf1 neurofibromin 1 IEA KEGG rno:04010 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 IEA KEGG rno:04010 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 IEA KEGG rno:04010 NCBI chr15:34,493,163...34,502,238
Ensembl chr15:34,493,138...34,504,326
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IEA KEGG rno:04010 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 IEA KEGG rno:04010 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Ngf nerve growth factor IEA KEGG rno:04010 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nlk nemo like kinase IEA KEGG rno:04010 NCBI chr10:65,840,052...65,963,932
Ensembl chr10:65,840,052...65,963,932
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 IEA KEGG rno:04010 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nras NRAS proto-oncogene, GTPase IEA KEGG rno:04010 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
JBrowse link
G Ntf3 neurotrophin 3 IEA KEGG rno:04010 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Ntf4 neurotrophin 4 IEA KEGG rno:04010 NCBI chr 1:101,405,314...101,408,145
Ensembl chr 1:101,405,314...101,408,145
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEA KEGG rno:04010 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEA KEGG rno:04010 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 TAS
IEA
KEGG PMID:9779826 rno:04010, RGD:70317 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 IEA KEGG rno:04010 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Pdgfa platelet derived growth factor subunit A IEA KEGG rno:04010 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B IEA KEGG rno:04010 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEA KEGG rno:04010 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEA KEGG rno:04010 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pla2g10 phospholipase A2, group X IEA KEGG rno:04010 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Pla2g12a phospholipase A2, group XIIA IEA KEGG rno:04010 NCBI chr 2:235,311,664...235,327,972
Ensembl chr 2:235,311,719...235,327,972
JBrowse link
G Pla2g12b phospholipase A2, group XIIB IEA KEGG rno:04010 NCBI chr20:28,989,440...29,007,967
Ensembl chr20:28,989,491...29,007,968
JBrowse link
G Pla2g1b phospholipase A2 group IB IEA KEGG rno:04010 NCBI chr12:46,879,346...46,890,234
Ensembl chr12:46,879,343...46,889,082
JBrowse link
G Pla2g2a phospholipase A2 group IIA IEA KEGG rno:04010 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Pla2g2c phospholipase A2, group IIC IEA KEGG rno:04010 NCBI chr 5:157,163,672...157,187,654
Ensembl chr 5:157,165,341...157,187,643
JBrowse link
G Pla2g2d phospholipase A2, group IID IEA KEGG rno:04010 NCBI chr 5:157,222,636...157,228,795
Ensembl chr 5:157,222,636...157,228,791
JBrowse link
G Pla2g2f phospholipase A2, group IIF IEA KEGG rno:04010 NCBI chr 5:157,192,047...157,217,265
Ensembl chr 5:157,193,053...157,199,441
JBrowse link
G Pla2g3 phospholipase A2, group III IEA KEGG rno:04010 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link
G Pla2g4a phospholipase A2 group IVA IEA KEGG rno:04010 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pla2g4b phospholipase A2 group IVB IEA KEGG rno:04010 NCBI chr 3:111,824,919...111,833,526
Ensembl chr 3:111,825,162...111,834,210
JBrowse link
G Pla2g4e phospholipase A2, group IVE IEA KEGG rno:04010 NCBI chr 3:111,952,396...112,018,470
Ensembl chr 3:111,952,348...111,994,337
JBrowse link
G Pla2g4f phospholipase A2, group IVF IEA KEGG rno:04010 NCBI chr 3:112,068,617...112,083,978
Ensembl chr 3:112,072,330...112,084,144
JBrowse link
G Pla2g5 phospholipase A2, group V IEA KEGG rno:04010 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link
G Pla2g6 phospholipase A2 group VI IEA KEGG rno:04010 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A IEA KEGG rno:04010 NCBI chr 6:94,433,658...94,484,979
Ensembl chr 6:94,429,068...94,484,351
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B IEA KEGG rno:04010 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IEA KEGG rno:04010 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IEA KEGG rno:04010 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma IEA KEGG rno:04010 NCBI chr15:51,896,427...51,968,075
Ensembl chr15:51,896,615...51,967,897
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha IEA KEGG rno:04010 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta IEA KEGG rno:04010 NCBI chr 5:64,945,583...64,946,578
Ensembl chr 5:64,945,583...64,946,580
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit IEA KEGG rno:04010 NCBI chr 1:78,944,054...78,968,361
Ensembl chr 1:78,944,040...78,968,329
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEA KEGG rno:04010 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta IEA KEGG rno:04010 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Prkca protein kinase C, alpha IEA KEGG rno:04010 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcb protein kinase C, beta IEA KEGG rno:04010 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcg protein kinase C, gamma IEA KEGG rno:04010 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Prkx protein kinase, X-linked IEA KEGG rno:04010 NCBI chr  X:45,080,963...45,125,095
Ensembl chr  X:45,080,963...45,124,270
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IEA KEGG rno:04010 NCBI chr 1:103,197,918...103,258,309
Ensembl chr 1:103,197,915...103,256,823
JBrowse link
G Ptpn7 protein tyrosine phosphatase, non-receptor type 7 IEA KEGG rno:04010 NCBI chr13:51,958,023...51,971,431
Ensembl chr13:51,958,834...51,972,777
JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R IEA KEGG rno:04010 NCBI chr 7:59,039,717...59,325,925
Ensembl chr 7:59,039,720...59,325,947
JBrowse link
G Rac1 Rac family small GTPase 1 IEA KEGG rno:04010 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rac2 Rac family small GTPase 2 IEA KEGG rno:04010 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase IEA KEGG rno:04010 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IEA KEGG rno:04010 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family IEA KEGG rno:04010 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 IEA KEGG rno:04010 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157
JBrowse link
G Rasa1 RAS p21 protein activator 1 IEA KEGG rno:04010 NCBI chr 2:13,617,021...13,696,531
Ensembl chr 2:13,616,822...13,696,426
JBrowse link
G Rasa2 RAS p21 protein activator 2 IEA KEGG rno:04010 NCBI chr 8:104,417,827...104,542,313
Ensembl chr 8:104,414,567...104,542,317
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEA KEGG rno:04010 NCBI chr 8:97,277,250...97,405,095
Ensembl chr 8:97,277,456...97,405,102
JBrowse link
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 IEA KEGG rno:04010 NCBI chr 2:21,460,041...21,698,937 JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA KEGG rno:04010 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 IEA KEGG rno:04010 NCBI chr 1:221,771,238...221,788,765
Ensembl chr 1:221,773,254...221,788,765
JBrowse link
G Rasgrp3 RAS guanyl releasing protein 3 IEA KEGG rno:04010 NCBI chr 6:21,072,634...21,171,619
Ensembl chr 6:21,072,634...21,135,880
JBrowse link
G Rasgrp4 RAS guanyl releasing protein 4 IEA KEGG rno:04010 NCBI chr 1:88,078,350...88,094,331
Ensembl chr 1:88,078,350...88,094,330
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEA KEGG rno:04010 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1564956 similar to calcium binding protein P22 IEA KEGG rno:04010 NCBI chr 5:70,747,534...70,749,967 JBrowse link
G RGD1565395 similar to stathmin 1/oncoprotein 18) IEA KEGG rno:04010 NCBI chr10:83,147,416...83,147,903 JBrowse link
G RGD1565588 similar to calcium binding protein P22 IEA KEGG rno:04010 NCBI chr 4:6,477,461...6,479,158 JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 IEA KEGG rno:04010 NCBI chr 5:152,078,217...152,122,684
Ensembl chr 5:152,078,220...152,122,684
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 IEA KEGG rno:04010 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 IEA KEGG rno:04010 NCBI chr  X:37,469,736...37,576,055
Ensembl chr  X:37,469,937...37,575,624
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 IEA KEGG rno:04010 NCBI chr 6:124,557,892...124,735,787
Ensembl chr 6:124,557,913...124,735,778
JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 IEA KEGG rno:04010 NCBI chr  X:82,641,679...82,743,771
Ensembl chr  X:82,641,687...82,743,753
JBrowse link
G Rras RAS related IEA KEGG rno:04010 NCBI chr 1:101,012,822...101,016,720
Ensembl chr 1:101,012,822...101,016,720
JBrowse link
G Rras2 RAS related 2 IEA KEGG rno:04010 NCBI chr 1:178,940,515...179,010,257
Ensembl chr 1:178,940,516...179,010,257
JBrowse link
G Shc1 SHC adaptor protein 1 IDA RGD PMID:12837289 RGD:1304398 NCBI chr 2:188,745,503...188,757,066
Ensembl chr 2:188,745,503...188,757,066
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IEA KEGG rno:04010 NCBI chr 6:3,105,443...3,182,977
Ensembl chr 6:3,104,861...3,182,996
JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 IEA KEGG rno:04010 NCBI chr 6:91,885,292...92,008,059
Ensembl chr 6:91,883,425...92,007,957
JBrowse link
G Srf serum response factor IEA KEGG rno:04010 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Stk3 serine/threonine kinase 3 IEA KEGG rno:04010 NCBI chr 7:73,617,926...73,883,896
Ensembl chr 7:73,618,644...73,883,812
JBrowse link
G Stk4 serine/threonine kinase 4 IEA KEGG rno:04010 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540
JBrowse link
G Stmn1 stathmin 1 IEA KEGG rno:04010 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Taok1 TAO kinase 1 IEA KEGG rno:04010 NCBI chr10:62,542,870...62,630,341
Ensembl chr10:62,566,732...62,630,155
JBrowse link
G Taok2 TAO kinase 2 IEA KEGG rno:04010 NCBI chr 1:198,301,789...198,354,601
Ensembl chr 1:198,301,938...198,320,075
JBrowse link
G Taok3 TAO kinase 3 IEA KEGG rno:04010 NCBI chr12:45,037,951...45,116,593
Ensembl chr12:45,037,883...45,182,974
JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEA KEGG rno:04010 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEA KEGG rno:04010 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IEA KEGG rno:04010 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 IEA KEGG rno:04010 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEA KEGG rno:04010 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tnf tumor necrosis factor IEA KEGG rno:04010 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEA KEGG rno:04010 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 IEA KEGG rno:04010 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Traf2 Tnf receptor-associated factor 2 IEA KEGG rno:04010 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Traf6 TNF receptor associated factor 6 IEA KEGG rno:04010 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:14612383 RGD:1580517 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
altered Erk5 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k5 mitogen activated protein kinase kinase 5 ISO RGD PMID:16376520 RGD:2298532 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO RGD PMID:16376520 RGD:2298532 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
altered extracellular signal-regulated Raf/Mek/Erk signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO RGD PMID:17126425, PMID:21277552, PMID:20951313, PMID:18098337 RGD:2293882, RGD:5133243, RGD:5133242, RGD:2298531 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Kras KRAS proto-oncogene, GTPase TAS
ISO
RGD PMID:16112461, PMID:18772397, PMID:19506583, PMID:20951313, PMID:19078924 RGD:2306732, RGD:5490966, RGD:5490965, RGD:5133242, RGD:4143515 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO RGD PMID:20951313, PMID:21277552 RGD:5133242, RGD:5133243 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO RGD PMID:17126425 RGD:2293882 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
c-Jun N-terminal kinases MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 ISO RGD PMID:8910292, PMID:9305638 RGD:2293876, RGD:2293879 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO RGD PMID:17208316 RGD:2293881 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp10 dual specificity phosphatase 10 ISO RGD PMID:17208316 RGD:2293881 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dusp16 dual specificity phosphatase 16 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
JBrowse link
G Dusp19 dual specificity phosphatase 19 ISO RGD PMID:11959862 RGD:2314491 NCBI chr 3:67,849,966...67,862,475
Ensembl chr 3:67,849,966...67,862,475
JBrowse link
G Dusp8 dual specificity phosphatase 8 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO
IDA
RGD PMID:17306896, PMID:12524169, PMID:17064355, PMID:10051439 RGD:2293875, RGD:2298708, RGD:2298577, RGD:2298561 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO
IDA
RGD PMID:17306896, PMID:17064355, PMID:15680699, PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298567, RGD:2298561 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9305638, PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 1:84,473,178...84,491,689
Ensembl chr 1:84,473,071...84,491,466
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO
IDA
RGD PMID:8910292, PMID:17064355, PMID:15680699, PMID:17306896 RGD:2293876, RGD:2298577, RGD:2298567, RGD:2293875 NCBI chr 1:221,043,119...221,056,420
Ensembl chr 1:221,043,119...221,056,417
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 ISO RGD PMID:17306896 RGD:2293875 NCBI chr11:82,744,391...82,938,357
Ensembl chr11:82,745,735...82,938,357
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 ISO RGD PMID:9305638, PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr18:24,961,250...25,025,488
Ensembl chr18:24,961,245...25,025,897
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369
JBrowse link
G Map3k21 mitogen-activated protein kinase kinase kinase 21 ISO RGD PMID:17306896 RGD:2293875 NCBI chr19:58,744,995...58,779,408
Ensembl chr19:58,746,313...58,776,935
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO RGD PMID:9305638, PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr10:94,280,703...94,349,372
Ensembl chr10:94,280,703...94,349,368
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO RGD PMID:9305638, PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr 1:48,625,714...48,711,642
Ensembl chr 1:48,625,743...48,711,642
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:12215209, PMID:17306896 RGD:2293875, RGD:2296020 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
JBrowse link
G Map3k9 mitogen-activated protein kinase kinase kinase 9 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 6:105,455,461...105,518,974
Ensembl chr 6:105,459,706...105,518,748
JBrowse link
G Mapk10 mitogen activated protein kinase 10 ISO
IDA
RGD PMID:17306896, PMID:15680699, PMID:10051439 RGD:2293875, RGD:2298567, RGD:2298561 NCBI chr14:8,079,955...8,371,508
Ensembl chr14:8,080,275...8,368,254
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO
IDA
RGD PMID:17306896, PMID:17064355, PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298561 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 ISO
IDA
RGD PMID:17726577, PMID:15816852 RGD:2293880, RGD:1579811 NCBI chr 3:81,295,023...81,304,181
Ensembl chr 3:81,295,024...81,304,181
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 ISO RGD PMID:17726577 RGD:2293880 NCBI chr 7:130,430,588...130,440,838
Ensembl chr 7:130,431,213...130,440,703
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 ISO RGD PMID:17726577 RGD:2293880 NCBI chr10:14,259,394...14,299,276
Ensembl chr10:14,260,787...14,299,167
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO
IDA
RGD PMID:17306896, PMID:17064355, PMID:10051439 RGD:2293875, RGD:2298577, RGD:2298561 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Rac1 Rac family small GTPase 1 ISO RGD PMID:8910292, PMID:9305638 RGD:2293876, RGD:2293879 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:10811109 RGD:11534984 NCBI chr 3:8,189,594...8,307,077
Ensembl chr 3:8,192,575...8,304,976
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15757900 RGD:1581337 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO RGD PMID:12215209 RGD:2296020 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
Erk5 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k5 mitogen activated protein kinase kinase 5 ISO
IMP
RGD PMID:16376520, PMID:15631999 RGD:2298532, RGD:1582263 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 ISO RGD PMID:16376520 RGD:2298532 NCBI chr18:24,961,250...25,025,488
Ensembl chr18:24,961,245...25,025,897
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO RGD PMID:16376520 RGD:2298532 NCBI chr10:94,280,703...94,349,372
Ensembl chr10:94,280,703...94,349,368
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO
IMP
RGD PMID:16376520, PMID:11782488 RGD:2298532, RGD:2298794 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Sh2d2a SH2 domain containing 2A ISO RGD PMID:16376520 RGD:2298532 NCBI chr 2:187,218,851...187,225,000
Ensembl chr 2:187,218,851...187,225,002
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 ISO RGD PMID:16376520 RGD:2298532 NCBI chr 4:152,452,211...152,578,469
Ensembl chr 4:152,452,848...152,578,446
JBrowse link
p38 MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin IMP RGD PMID:16157033 RGD:1625329 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Atm ATM serine/threonine kinase ISO PID PID:200018 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Bnip2 BCL2 interacting protein 2 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 8:76,400,333...76,426,307
Ensembl chr 8:76,400,341...76,426,503
JBrowse link
G Calm1 calmodulin 1 ISO PID PID:200018 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 ISO PID PID:200018 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 ISO PID PID:200018 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO PID PID:200018 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Ccm2 CCM2 scaffold protein ISO PID PMID:17481747, PMID:20626350 PID:200018, RGD:2293891, RGD:7240533 NCBI chr14:86,812,728...86,859,408
Ensembl chr14:86,813,082...86,859,406
JBrowse link
G Cdc42 cell division cycle 42 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdon cell adhesion associated, oncogene regulated ISO RGD PMID:20626350 RGD:7240533 NCBI chr 8:36,625,757...36,712,091
Ensembl chr 8:36,625,733...36,710,949
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp10 dual specificity phosphatase 10 ISO RGD PMID:20626350 RGD:7240533 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dusp16 dual specificity phosphatase 16 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
JBrowse link
G Dusp9 dual specificity phosphatase 9 ISO RGD PMID:20626350 RGD:7240533 NCBI chr  X:157,168,143...157,172,068
Ensembl chr  X:157,168,144...157,172,068
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO PID PID:200018 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta ISO PID PID:200018 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma ISO PID PID:200018 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:15141302 RGD:5128786 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 ISO
IDA
PID PMID:17481747, PMID:16183734 PID:200018, RGD:2293891, RGD:2298758 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO
IDA
PID PMID:17481747, PMID:16183734 PID:200018, RGD:2293891, RGD:2298758 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO PID PID:200018 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 ISO PID PID:200018 NCBI chr 1:84,473,178...84,491,689
Ensembl chr 1:84,473,071...84,491,466
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 1:221,043,119...221,056,420
Ensembl chr 1:221,043,119...221,056,417
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 ISO RGD PMID:20626350 RGD:7240533 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO PID PMID:17481747, PMID:20626350 PID:200018, RGD:2293891, RGD:7240533 NCBI chr10:94,280,703...94,349,372
Ensembl chr10:94,280,703...94,349,368
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO PID PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:48,625,714...48,711,642
Ensembl chr 1:48,625,743...48,711,642
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO PID PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 ISO PID PID:200018 NCBI chr 5:151,435,679...151,448,329
Ensembl chr 5:151,436,464...151,448,328
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO
IDA
PID PMID:17481747, PMID:20626350, PMID:16183734 PID:200018, RGD:2293891, RGD:7240533, RGD:2298758 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ISO RGD PMID:20626350 RGD:7240533 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO PID PMID:17481747 PID:200018, RGD:2293891 NCBI chr 7:130,121,678...130,129,199
Ensembl chr 7:130,121,687...130,128,604
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 ISO RGD PMID:17481747 RGD:2293891 NCBI chr 7:130,109,214...130,120,918
Ensembl chr 7:130,109,663...130,120,579
JBrowse link
G Mapk13 mitogen activated protein kinase 13 ISO RGD PMID:17481747 RGD:2293891 NCBI chr20:6,018,374...6,027,467
Ensembl chr20:6,018,374...6,027,473
JBrowse link
G Mapk14 mitogen activated protein kinase 14 IDA
ISO
PID PMID:16407200, PMID:17481747 PID:200018, RGD:1580544, RGD:2293891 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 ISO
IMP
RGD PMID:17481747, PMID:12024021 RGD:2293891, RGD:2302280 NCBI chr 7:130,430,588...130,440,838
Ensembl chr 7:130,431,213...130,440,703
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 8:116,012,126...116,046,012
Ensembl chr 8:116,012,121...116,045,954
JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr12:40,510,378...40,529,332
Ensembl chr12:40,510,378...40,529,338
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 5:134,691,852...134,730,887
Ensembl chr 5:134,691,881...134,730,893
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
G Rac1 Rac family small GTPase 1 ISO PID PMID:17481747 PID:200018, RGD:2293891 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:222,087,328...222,098,284
Ensembl chr 1:222,087,326...222,098,297
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 6:124,557,892...124,735,787
Ensembl chr 6:124,557,913...124,735,778
JBrowse link
G Spag9 sperm associated antigen 9 ISO RGD PMID:20626350 RGD:7240533 NCBI chr10:81,693,736...81,827,562
Ensembl chr10:81,693,770...81,827,562
JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 ISO PID PID:200018 NCBI chr 7:121,350,953...121,382,100
Ensembl chr 7:121,350,965...121,382,088
JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO PID PID:200018 NCBI chr 1:1,999,574...2,017,574
Ensembl chr 1:1,999,596...2,073,896
JBrowse link
G Taok1 TAO kinase 1 ISO PID PMID:20626350 PID:200018, RGD:7240533 NCBI chr10:62,542,870...62,630,341
Ensembl chr10:62,566,732...62,630,155
JBrowse link
G Taok2 TAO kinase 2 ISO PID PMID:20626350 PID:200018, RGD:7240533 NCBI chr 1:198,301,789...198,354,601
Ensembl chr 1:198,301,938...198,320,075
JBrowse link
G Taok3 TAO kinase 3 ISO PID PID:200018 NCBI chr12:45,037,951...45,116,593
Ensembl chr12:45,037,883...45,182,974
JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO PID PMID:12215209 PID:200018, RGD:2296020 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO PID PMID:20626350 PID:200018, RGD:7240533 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Txn1 thioredoxin 1 ISO PID PID:200018 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
the extracellular signal-regulated Raf/Mek/Erk signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Araf A-Raf proto-oncogene, serine/threonine kinase ISO RGD PMID:22177953 RGD:5686410 NCBI chr  X:1,369,534...1,391,603
Ensembl chr  X:1,379,194...1,390,873
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase IMP
ISO
RGD PMID:16508002, PMID:22177953, PMID:17310240 RGD:1580106, RGD:5686410, RGD:1626216 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Dusp6 dual specificity phosphatase 6 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IMP RGD PMID:20445128 RGD:4892084 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO RGD PMID:22177953 RGD:5686410 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Kras KRAS proto-oncogene, GTPase IDA
ISO
RGD PMID:12388314, PMID:22177953 RGD:628557, RGD:5686410 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Ksr1 kinase suppressor of ras 1 ISO RGD PMID:17726577, PMID:22177953 RGD:2293880, RGD:5686410 NCBI chr10:66,323,704...66,342,469
NCBI chr10:66,346,100...66,482,396
Ensembl chr10:66,347,358...66,482,150
JBrowse link
G Ksr2 kinase suppressor of ras 2 ISO RGD PMID:22177953 RGD:5686410 NCBI chr12:44,531,376...44,911,835
Ensembl chr12:44,536,293...44,911,147
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 TAS
IMP
RGD PMID:9779826, PMID:17310240 RGD:70317, RGD:1626216 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 NAS
IMP
RGD PMID:8462694, PMID:17310240 RGD:729046, RGD:1626216 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISS
ISO
RGD PMID:12835716, PMID:9305638 RGD:1357969, RGD:2293879 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 NAS RGD PMID:11359865 RGD:724475 NCBI chr18:24,961,250...25,025,488
Ensembl chr18:24,961,245...25,025,897
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA
IMP
RGD PMID:12097495, PMID:16955078, PMID:17310240 RGD:628468, RGD:8553011, RGD:1626216 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA
ISO
IMP
RGD PMID:12097495, PMID:20080775, PMID:16955078, PMID:17310240 RGD:628468, RGD:5508172, RGD:8553011, RGD:1626216 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO
IMP
RGD PMID:16421520, PMID:16955078 RGD:2315047, RGD:8553011 NCBI chr 5:134,691,852...134,730,887
Ensembl chr 5:134,691,881...134,730,893
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO RGD PMID:22177953 RGD:5686410 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 TAS
IMP
RGD PMID:17126425, PMID:10490027 RGD:2293882, RGD:2302807 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Prkcd protein kinase C, delta IMP RGD PMID:12790799 RGD:1642529 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15096502 RGD:1642630 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase TAS
ISO
IMP
RGD PMID:9779826, PMID:22177953, PMID:17310240, PMID:16508002 RGD:70317, RGD:5686410, RGD:1626216, RGD:1580106 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 5:152,078,217...152,122,684
Ensembl chr 5:152,078,220...152,122,684
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 ISO RGD PMID:16421520 RGD:2315047 NCBI chr  X:37,469,736...37,576,055
Ensembl chr  X:37,469,937...37,575,624
JBrowse link
G Rps6ka4 ribosomal protein S6 kinase A4 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 1:222,087,328...222,098,284
Ensembl chr 1:222,087,326...222,098,297
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 ISO RGD PMID:16421520 RGD:2315047 NCBI chr 6:124,557,892...124,735,787
Ensembl chr 6:124,557,913...124,735,778
JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 ISO RGD PMID:16421520 RGD:2315047 NCBI chr  X:82,641,679...82,743,771
Ensembl chr  X:82,641,687...82,743,753
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IMP RGD PMID:14711826 RGD:1304283 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Shc1 SHC adaptor protein 1 IEP RGD PMID:16699171 RGD:1643182 NCBI chr 2:188,745,503...188,757,066
Ensembl chr 2:188,745,503...188,757,066
JBrowse link
G Smad1 SMAD family member 1 IMP RGD PMID:16427075 RGD:1643230 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15757900 RGD:1581337 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tsc2 TSC complex subunit 2 ISO RGD PMID:15150271 RGD:1580097 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link

Pathway Gene Annotations

Disease Annotations Associated with Genes in the mitogen activated protein kinase signaling pathway