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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
antianxiety agent +    
receptor antagonist +     
2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline 
2-methyl-6-(phenylethynyl)pyridine 
This is any condition in which the main influencing factor is 2-methyl-6-(phenylethynyl)pyridine, a methylpyridine that consists of 2-methylpyridine bearing an additional phenylethynyl group at position 6. It is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. It functions as an excitatory amino acid antagonist and an anxiolytic agent.
adrenergic antagonist +  
almorexant 
alpidem 
angiotensin II receptor antagonist +   
caffeine +  
Capsazepine 
cenicriviroc 
chlormezanone 
cholinergic antagonist +   
cimetidine 
clozapine 
diallyl trisulfide 
diphenhydramine 
endothelin receptor antagonist +  
flutamide 
GSK-812 
hydroxyzine 
icatibant 
ionotropic glutamate receptor antagonist +  
metiamide 
mineralocorticoid receptor antagonist +  
MK-3207 
NMDA receptor antagonist +  
olanzapine 
panadiplon 
paroxetine 
pentolinium  
phenobarbital +  
propranolol 
salidroside 
semaxanib 
sunitinib 
telcagepant 
ticlopidine +  
tolvaptan +  
zafirlukast 

Synonyms
Exact Synonyms: MPEP
Xrefs: PMID:28615682
Definition Sources: CHEBI:64159, MESH:C121465

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