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Pathways
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Term:
Parent Terms Term With Siblings Child Terms
anti-estrogen drug pathway +     
axitinib drug pathway +     
bortezomib drug pathway +  
capecitabine drug pathway +   
cyclophosphamide drug pathway +   
docetaxel drug pathway +   
doxorubicin drug pathway +     
erlotinib drug pathway +   
etoposide drug pathway +   
everolimus drug pathway +  
gefitinib drug pathway +     
gemcitabine pathway +   
ifosfamide drug pathway +   
irinotecan drug pathway +   
mercaptopurine drug pathway +   
methotrexate drug pathway +   
monoclonal antibody drug pathway +   
pazopanib drug pathway +  
pemetrexed drug pathway +  
platinum (Pt) containing drug pathway +    
plevitrexed drug pathway +  
pralatrexate drug pathway +  
sorafenib drug pathway +   
sunitinib drug pathway +  
temsirolimus drug pathway +  
The pharmacokinetics and pharmacodynamics pathway of temsirolimus, an inhibitor of mTOR pathway used in the treatment of renal cell carcinoma and other types of tumors. Hypoxia inducible factor (HIF) pathway is constitutively active in renal cell carcinoma; HIF-alpha translation is under the control of mTOR pathway. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
teniposide drug pathway +   
tioguanine drug pathway +   
vinca alkaloid drug pathway +   

Synonyms
Definition Sources: PMID:20456985

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