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Pathways
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Term:
Parent Terms Term With Siblings Child Terms
anti-estrogen drug pathway +     
axitinib drug pathway +     
The pharmacokinetics and pharmacodynamics pathway of axitinib, a receptor tyrosine kinase inhibitor used in the treatment of renal cell carcinoma as well as other tumors. Angiogenic factors such as vascular endothelial or platelet derived growth factors are direct and indirect targets of hypoxia inducible factor pathway, constitutively active in renal cell carcinoma. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
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bortezomib drug pathway +  
capecitabine drug pathway +   
cyclophosphamide drug pathway +   
docetaxel drug pathway +   
doxorubicin drug pathway +     
erlotinib drug pathway +   
etoposide drug pathway +   
everolimus drug pathway +  
gefitinib drug pathway +     
gemcitabine pathway +   
ifosfamide drug pathway +   
irinotecan drug pathway +   
mercaptopurine drug pathway +   
methotrexate drug pathway +   
monoclonal antibody drug pathway +   
pazopanib drug pathway +  
pemetrexed drug pathway +  
platinum (Pt) containing drug pathway +    
plevitrexed drug pathway +  
pralatrexate drug pathway +  
sorafenib drug pathway +   
sunitinib drug pathway +  
temsirolimus drug pathway +  
teniposide drug pathway +   
tioguanine drug pathway +   
vinca alkaloid drug pathway +   

Synonyms
Definition Sources: PMID:22170007

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