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Pathways
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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
anti-estrogen drug pathway +     
axitinib drug pathway +     
bortezomib drug pathway +  
capecitabine drug pathway +   
cyclophosphamide drug pathway +   
docetaxel drug pathway +   
doxorubicin drug pathway +     
erlotinib drug pathway +   
etoposide drug pathway +   
everolimus drug pathway +  
gefitinib drug pathway +     
gemcitabine pathway +   
ifosfamide drug pathway +   
irinotecan drug pathway +   
mercaptopurine drug pathway +   
methotrexate drug pathway +   
monoclonal antibody drug pathway +   
pazopanib drug pathway +  
pemetrexed drug pathway +  
platinum (Pt) containing drug pathway +    
plevitrexed drug pathway +  
pralatrexate drug pathway +  
sorafenib drug pathway +   
sunitinib drug pathway +  
The pharmacokinetics and pharmacodynamics pathway of sunitinib, a multikinase inhibitor used in the treatment of cancer, in particular for advanced renal cell carcinoma. The drug binds to the intracytoplasmic domain of tyrosine kinase receptors blocking the downstream signaling cascade. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
temsirolimus drug pathway +  
teniposide drug pathway +   
tioguanine drug pathway +   
vinca alkaloid drug pathway +   

Synonyms
Definition Sources: PMID:22328304

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