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Ontology Browser

cytokine and chemokine mediated signaling pathway (PW:0000577)
Annotations: Rat: (573) Mouse: (344) Human: (352) Chinchilla: (318) Bonobo: (337) Dog: (334) Squirrel: (321) Pig: (331)     Pathway Diagram Browser
Parent Terms Term With Siblings Child Terms
signaling pathway +      
acid and base sensing signaling pathway +  
altered signaling pathway +    
calcium/calcium-mediated signaling pathway +     
cell adhesion signaling pathway +    
chemical compound signaling pathway +    
cytokine and chemokine mediated signaling pathway +    
Cytokines are small proteins released by the cell and acting as intercellular mediators. Chemokines are a subset of cytokine that can attract and activate leukocytes. They are characterized by a small size and the presence of four cysteines whose location is important for their structural folding. Cytokines or chemokines binding to cognate receptors triggers numerous downstream signaling cascades.
G protein mediated signaling pathway +   
glycoconjugated protein signaling pathway +    
growth factor signaling pathway +    
hormone signaling pathway +    
kinase mediated signaling pathway +    
lipid signaling pathway +   
mechanotransduction pathway +    
mitogen activated protein kinase signaling pathway +     
nucleoside and nucleotide mediated signaling pathway +   
phosphatase mediated signaling pathway +   
photosignal transduction pathway +    
protease mediated signaling pathway +   
signaling pathway involving second messengers +    
signaling pathway pertinent to development +    
signaling pathway pertinent to immunity +    
signaling pathway pertinent to the brain and nervous system +    
transcription factor mediated signaling pathway +    
vitamin and vitamin metabolites signaling pathway +    

Definition Sources: MCW library:Handbook on molecular and cellular immunology

paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.