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Term:
mitogen activated protein kinase signaling pathway (PW:0000007)
Annotations: Rat: (300) Mouse: (301) Human: (301) Chinchilla: (100) Bonobo: (100) Dog: (100) Squirrel: (100) Pig: (101)     Pathway Diagram Browser
Parent Terms Term With Siblings Child Terms
acid and base sensing signaling pathway +  
altered serine/threonine-specific kinase mediated signaling pathway +   
altered signaling pathway +    
ataxia telangiectasia-mutated (ATM) signaling pathway   
ATM and Rad3-related (ATR) signaling pathway 
calcium/calcium-mediated signaling pathway +     
calcium/calmodulin dependent kinase signaling pathway +    
cell adhesion signaling pathway +    
chemical compound signaling pathway +    
cytokine and chemokine mediated signaling pathway +    
G protein mediated signaling pathway +   
glycoconjugated protein signaling pathway +    
growth factor signaling pathway +    
Hippo signaling pathway +  
hormone signaling pathway +    
kinase mediated signaling pathway +    
lipid signaling pathway +   
mechanotransduction pathway +    
mitogen activated protein kinase signaling pathway +     
The mitogen-activated protein kinase pathway groups several serine/threonine protein kinases mediated cascades in response to a number of extracellular stimuli. A characteristic feature of these cascades is the presence of at least three kinases in series leading to the activation of a multifunctional MAP kinase.

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nucleoside and nucleotide mediated signaling pathway +   
phosphatase mediated signaling pathway +   
phosphatidylinositol 3-kinase-Akt signaling pathway +    
photosignal transduction pathway +    
protease mediated signaling pathway +   
protein kinase A (PKA) signaling pathway   
protein kinase C (PKC) signaling pathway   
signaling pathway involving second messengers +    
signaling pathway pertinent to development +    
signaling pathway pertinent to immunity +    
signaling pathway pertinent to the brain and nervous system +    
transcription factor mediated signaling pathway +    
vitamin and vitamin metabolites signaling pathway +    

Synonyms
Related Synonyms: KEGG:04010 ;   MAPK family signaling cascades ;   MAPK signaling pathway
Alternate IDs: Reactome:R-HSA-5683057
Definition Sources: GO:0000165, KEGG:map04010, PMID:14570565, PMID:14976517, PMID:17229475, PMID:17306385

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.