decreased susceptibility to myocardial ischemic injury +
increased response of heart to induced stress
increased susceptibility to ischemic brain injury +
increased susceptibility to myocardial ischemic injury +
more severe response, such as increased incidence and/or size of necrotic tissue, to lack of adequate blood flow resulting from trauma or disease, to support the normal functioning of the myocardium compared to controls
increased susceptilbility to retina ischemic injury