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Ontology Browser

Term:
abnormal Leydig cell differentiation (MP:0013602)
Annotations: Rat: (2) Mouse: (14) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
abnormal Leydig cell differentiation +   
atypical formation of or inability to produce the interstitial cells that are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone; in most mammals, normal Leydig cell (LC) development comprises two sequential but overlapping cell lineages known as the fetal and adult type LC populations, which display distinct functional characteristics reflected by different morphology, hormonal regulation, and steroidogenic output
decreased Leydig cell number +   
ectopic Leydig cells  
increased Leydig cell number  
Leydig cell atrophy  
Leydig cell hypertrophy  

Synonyms
Exact Synonyms: abnormal LC differentiation
Definition Sources: http://press.endocrine.org/doi/full/10.1210/en.2012-2273, MGI:anna

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