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Ontology Browser

Term:
abnormal glomerular filtration barrier morphology (MP:0011855)
Annotations: Rat: (4) Mouse: (2) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
abnormal glomerular capillary morphology +   
abnormal glomerular filtration barrier morphology  
any structural anomaly of the highly specialized blood filtration interface that displays a high conductance to small and midsized solutes in plasma but retains relative impermeability to macromolecules; its integrity is maintained by physicochemical and signalling interplay among its three core constituents -- the fenestrated endothelium of the glomerular capillaries, the glomerular basement membrane, and the filtration slits of the visceral epithelial cell (podocyte)
abnormal glomerular mesangium morphology +   
abnormal susceptibility to glomerulonephritis +  
absent renal glomerulus  
cortical renal glomerulopathies +   
decreased renal glomerulus number  
glomerular crescent  
increased renal glomerulus lobularity  
renal glomerular protein deposits +   
renal glomerular synechia  
renal glomerulus atrophy  
renal glomerulus fibrosis  
renal glomerulus hypertrophy  
renal glomerulus lipidosis  

Synonyms
Exact Synonyms: abnormal GFB morphology
Definition Sources: MGI:anna, PMCID:PMC2895306

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