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Ontology Browser

Term:
abnormal interstitial cell of Cajal morphology (MP:0009536)
Annotations: Rat: (3) Mouse: (5) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
abnormal anal canal morphology +   
abnormal digestive organ placement +   
abnormal digestive system development +   
abnormal enteroendocrine cell morphology +   
abnormal esophagus morphology +   
abnormal exocrine pancreas morphology +   
abnormal gastrointestinal brush cell morphology  
abnormal interstitial cell of Cajal morphology +   
any structural anomaly in the type of cell found in the gastrointestinal tract and serving as a pacemaker that triggers gut contraction; ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumours (GISTs) arise; abnormalities in the ICC network can cause chronic intestinal pseudo-obstruction
abnormal intestine morphology +   
abnormal oral mucosa morphology +   
abnormal palate morphology +   
abnormal perineum morphology +   
abnormal salivary gland morphology +   
abnormal stomach morphology +   
abnormal throat morphology +   
abnormal tongue morphology +   
decreased alimentary system tumor incidence +   
gastrointestinal arteriovenous malformation  
gastrointestinal tract polyps +   
gastrointestinal ulcer +   
increased alimentary system tumor incidence +   
lymphomesenteric cyst 

Synonyms
Exact Synonyms: abnormal ICC morphology
Definition Sources: https://orcid.org/0000-0002-6490-7723, PMID:16460275

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