abnormal cumulus expansion - Ontology Browser

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abnormal cumulus expansion (MP:0009373)
Annotations: Rat: (0) Mouse: (14) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)

Parent Terms

Term With Siblings

Child Terms

abnormal ovarian folliculogenesis + is-a

abnormal cumulus expansion +

anomaly in the ability of the cumulus cells to synthesize and accumulate hyaluronan into an extracellular matrix (ECM), which provides an essential microenvironment for oocyte fertilization; this expanded ECM binds the oocyte and the cumulus cells together, protects the oocyte from the proteolytic and mechanical stresses during extrusion, and allows sperm binding, penetration, and fertilization

absent mature ovarian follicles

impaired ovarian folliculogenesis

increased follicle recruitment

absent cumulus expansion

decreased cumulus expansion

increased cumulus expansion

Synonyms
Exact Synonyms:	abnormal ovarian cumulus expansion ; abnormal ovarian cumulus growth
Definition Sources:	MGI:anna

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