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Pathways

Ontology Browser

Term:
abnormal inner hair cell stereociliary bundle morphology (MP:0004532)
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Parent Terms Term With Siblings Child Terms
abnormal cochlear hair cell inter-stereocilial links morphology +   
abnormal cochlear IHC afferent innervation pattern  
abnormal cochlear IHC efferent innervation pattern  
abnormal cochlear inner hair cell number +   
abnormal inner hair cell stereociliary bundle morphology +   
any structural anomaly or disruption of the typically linear or U-shaped pattern of arrangement of mechanosensitive hair bundles located at the apical end of cochlear IHCs; each hair bundle is normally composed of ~100 nonmotile, actin-filled microvilli (stereocilia) arranged in rows of increasing height and coupled to one another by morphologically distinct links: tip links, horizontal top connectors, shaft connectors, and ankle links; most hair bundles also possess a single motile kinocilium immediately adjacent to the tallest row of stereocilia; a fifth link type, the kinocilial link, connects the kinocilium to its neighboring stereocilia
abnormal inner hair cell synaptic ribbon morphology +   
abnormal orientation of cochlear hair cell stereociliary bundles +   
abnormal outer hair cell stereociliary bundle morphology +   
absent cochlear hair cell stereocilia  
cochlear inner hair cell degeneration  
decreased cochlear hair cell stereocilia number +   
short cochlear hair cell stereocilia +   
thin cochlear hair cell stereocilia  

Synonyms
Exact Synonyms: abnormal IHC bundles ;   abnormal IHC stereocilia ;   abnormal IHC stereociliary bundles
Definition Sources: https://orcid.org/0000-0002-6490-7723

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