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Ontology Browser

Term:
mRNA base-pairing translational repressor activity (GO:1903231)
Annotations: Rat: (195) Mouse: (242) Human: (344) Chinchilla: (0) Bonobo: (0) Dog: (196) Squirrel: (0) Pig: (150) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
iron-responsive element binding  
mRNA 3'-UTR binding +   
mRNA 5'-UTR binding  
mRNA base-pairing translational repressor activity  
A translation repressor activity that acts by base-pairing with an mRNA. The binding can result in targeting the mRNA for degradation or interfering with mRNA translation, hence resulting in posttranscriptional gene silencing.
mRNA cap binding  
mRNA CDS binding  
mRNA regulatory element binding translation repressor activity  
selenocysteine insertion sequence binding  
sequence-specific mRNA binding  
small RNA binding translational repressor activity 
translation repressor activity, non-nucleic acid binding  
triplet codon-amino acid adaptor activity +   

Synonyms
Exact Synonyms: mRNA base-pairing posttranscriptional repressor activity ;   mRNA binding involved in PTGS ;   mRNA binding involved in post-transcriptional gene silencing ;   mRNA binding involved in posttranscriptional gene silencing ;   mRNA binding involved in quelling ;   translational inhibitor activity via mRNA base-pairing
Broad Synonyms: RNA binding involved in PTGS ;   RNA binding involved in cosuppression ;   RNA binding involved in post-transcriptional gene silencing ;   RNA binding involved in posttranscriptional gene silencing ;   RNA binding involved in quelling ;   mRNA binding translation repressor activity
Related Synonyms: mRNA base-pairing post-transcriptional repressor activity ;   mRNA binding involved in cosuppression
Alternate IDs: GO:0150100
Definition Sources: GOC:BHF, GOC:BHF_miRNA, PMID:18197166, PMID:20533884

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