Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.
Reactome:R-HSA-266070 "LTC4 is exported from the cytosol by ABCC1"
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Reactome:R-HSA-429157 "ABCC4 accumulation of dense granule contents"
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Reactome:R-HSA-5362459 "VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol"
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Reactome:R-HSA-5387389 "Hh processing variants are translocated to the cytosol in a VCP-dependent manner"
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Reactome:R-HSA-9661405 "ABCC1 transports BIL from cytosol to extracellular region (blood)"
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Reactome:R-HSA-9750656 "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells"
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TC:3.A.1
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Wikipedia:ATP-binding_cassette_transporter