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Ontology Browser

Term:
all-trans-retinol dehydrogenase (NADP+) activity (GO:0052650)
Annotations: Rat: (11) Mouse: (13) Human: (13) Chinchilla: (5) Bonobo: (10) Dog: (8) Squirrel: (7) Pig: (10) Naked Mole-rat: (7) Green Monkey: (8)
Parent Terms Term With Siblings Child Terms
2-methylbutanal reductase (NADPH) activity 
3-methylbutanal reductase (NADPH) activity 
aldose reductase (NADPH) activity +   
all-trans-retinol dehydrogenase (NADP+) activity  
Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+.
carbonyl reductase (NADPH) activity  

Synonyms
Broad Synonyms: all-trans retinal reductase activity ;   all-trans-retinol dehydrogenase activity ;   retinol dehydrogenase activity
Related Synonyms: NADP(H)-dependent retinol dehydrogenase/reductase activity ;   retinol dehydrogenase [NADP+] activity ;   retinol:NADP+ oxidoreductase activity
Xrefs: EC:1.1.1.300 ;   KEGG_REACTION:R08379 ;   MetaCyc:RXN-10841 ;   RHEA:25033 ;   Reactome:R-HSA-2466861 "Defective RDH12 does not reduce atRAL to atROL" ;   reactome:R-HSA-2464803 "RDH8 reduces atRAL to atROL" ;   reactome:R-HSA-2464822 "RDH12 reduces atRAL to atROL" ;   reactome:R-HSA-2465921 "11cRDH oxidises 11cROL to 11cRAL" ;   reactome:R-HSA-2465940 "atRAL is reduced to atROL" ;   reactome:R-HSA-5419165 "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL"
Definition Sources: RHEA:25033

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