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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
DNA binding +     
bent DNA binding  
chromatin DNA binding +   
damaged DNA binding +   
DNA binding, bending +   
DNA end binding  
DNA secondary structure binding +   
DNA template activity +   
double-stranded DNA binding +   
flap-structured DNA binding +   
G-quadruplex DNA binding +   
Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.
histone-dependent DNA binding  
recombination hotspot binding  
sequence-specific DNA binding +   
single-stranded DNA binding +   
triplex DNA binding  

Synonyms
Exact Synonyms: G quartet DNA binding ;   G-DNA binding ;   quadruplex DNA binding ;   tetraplex DNA binding
Broad Synonyms: G quartet binding
Definition Sources: PMID:16142245, PMID:9512530

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