The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor.
glycoprotein catabolic process +
hemoglobin catabolic process
histone catabolic process
insulin catabolic process
lipoprotein catabolic process +
low-density lipoprotein particle receptor catabolic process +
mitochondrial protein catabolic process
negative regulation of epidermal growth factor receptor signaling pathway involved in heart process
negative regulation of epidermal growth factor-activated receptor activity
negative regulation of protein catabolic process +
positive regulation of protein catabolic process +
prosthetic group catabolic process
proteasomal protein catabolic process +
protein catabolic process at synapse +
protein catabolic process in the vacuole +
protein denaturation
proteolysis involved in protein catabolic process +
PSII associated light-harvesting complex II catabolic process +