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Term:
P-type sodium:potassium-exchanging transporter activity (GO:0005391)
Annotations: Rat: (10) Mouse: (10) Human: (10) Chinchilla: (7) Bonobo: (9) Dog: (9) Squirrel: (9) Pig: (9) Naked Mole-rat: (9) Green Monkey: (9) Black Rat: (6)
Parent Terms Term With Siblings Child Terms
P-type potassium:proton transporter activity  
P-type sodium:potassium-exchanging transporter activity +   
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).

Synonyms
Exact Synonyms: P-type sodium:potassium-exchanging ATPase activity;  sodium/potassium-exchanging ATPase activity;  sodium/potassium-transporting ATPase activity
Broad Synonyms: sodium pump
Related Synonyms: Na+,K+-ATPase activity;  Na+/K+-exchanging ATPase activity;  Na,K-activated ATPase activity
Xrefs: EC:7.2.2.13;  MetaCyc:3.6.3.9-RXN;  RHEA:18353;  Reactome:R-HSA-936897 "ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+";  TC:3.A.3.1.1;  Wikipedia:ATPase\,_Na%2B/K%2B_transporting\,_alpha_1
Definition Sources: EC:7.2.2.13

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