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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
4-hydroxybutyrate receptor activity  
advanced glycation end-product receptor activity  
auxin receptor activity 
carbon dioxide receptor activity 
cell adhesion receptor activity 
cord factor receptor activity 
coreceptor activity  
corticotropin-releasing hormone receptor activity  
diuretic hormone receptor activity 
DNA-binding transcription activator activity, RNA polymerase II-specific  
DNA-binding transcription repressor activity, RNA polymerase II-specific  
ethylene receptor activity +  
high molecular weight B cell growth factor receptor activity 
immune receptor activity +   
leucokinin receptor activity 
ligand-modulated transcription activator activity 
ligand-modulated transcription repressor activity 
neurotransmitter receptor activity +   
neurotrophin receptor activity +   
nuclear receptor activity +   
A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytosol, which leads to its translocation to the nucleus.
pattern recognition receptor activity +   
peptide receptor activity +   
phorbol ester receptor activity +   
photoreceptor activity +   
protein-hormone receptor activity +   
thrombospondin receptor activity  
transmembrane signaling receptor activity +   
urokinase plasminogen activator receptor activity  

Synonyms
Exact Synonyms: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
Narrow Synonyms: 1,25-(OH)2D3 receptor activity ;   9-cis retinoic acid receptor activity ;   RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding ;   RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding ;   RXR ;   androgen receptor activity ;   calcitriol receptor activity ;   ecdysteroid hormone receptor activity ;   estrogen nuclear receptor activity ;   glucocorticoid receptor activity
Related Synonyms: ligand-dependent nuclear receptor activity ;   ligand-dependent transcription factor activity
Alternate IDs: GO:0003708 ;   GO:0004880 ;   GO:0004882 ;   GO:0004884 ;   GO:0004886 ;   GO:0004887 ;   GO:0008434 ;   GO:0038050 ;   GO:0038051 ;   GO:0038052
Definition Sources: GOC:txnOH-2018, PMID:23457262

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