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Term:
Parent Terms Term With Siblings Child Terms
isocitrate dehydrogenase (NAD+) activity  
isocitrate dehydrogenase (NADP+) activity  
Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Synonyms
Related Synonyms: NADP isocitric dehydrogenase activity ;   NADP(+)-ICDH activity ;   NADP(+)-IDH activity ;   NADP-dependent isocitrate dehydrogenase activity ;   NADP-dependent isocitric dehydrogenase activity ;   NADP-linked isocitrate dehydrogenase activity ;   NADP-specific isocitrate dehydrogenase activity ;   dual-cofactor-specific isocitrate dehydrogenase activity ;   isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity ;   isocitrate:NADP+ oxidoreductase (decarboxylating)
Xrefs: EC:1.1.1.42 ;   MetaCyc:ISOCITDEH-RXN ;   RHEA:19629 ;   Reactome:R-HSA-450984 "IDH2 dimer decarboxylates isocitrate" ;   reactome:R-HSA-389540 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+" ;   reactome:R-HSA-389550 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+"
Definition Sources: RHEA:19629

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