Welcome
{{ username}}
Message Center
{{ messageCount }} Messages
Go to Message Center
Watched Genes
{{$index + 1}}.
{{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Modify Subscription
Unsubscribe
Watched Ontology Terms
{{$index + 1}}.
{{ watchedTerm.term }} ({{watchedTerm.accId}})
Modify Subscription
Unsubscribe
{{gene.symbol}}:
{{ gene.description }}
×
Save List to My RGD
Create Name:
Description:
You must be logged in to use this feature
{{ loginError }}
{{ watchLinkText }}
Select categories you would like to watch. Updates to this gene will be sent to {{ username }}
{{geneWatchAttr}}
Analyze
Gene
Strain
QTL
List
×
Gene Annotator (Functional Annotation)
unavailable
Gene Annotator (Annotation Distribution)
unavailable
Variant Visualizer (Genomic Variants)
unavailble
Variant Visualizer (Genomic Variants)
unavailable
Gene Annotator (Functional Annotation)
Gene Annotator (Annotation Distribution)
Variant Visualizer (Genomic Variants)
InterViewer (Protein-Protein Interactions)
unavailable
Gviewer (Genome Viewer)
unavailable
Variant Visualizer (Damaging Variants) unavailble
Variant Visualizer (Damaging Variants)
unavailable
InterViewer (Protein-Protein Interactions)
GViewer (Genome Viewer)
Variant Visualizer (Damaging Variants)
Gene Annotator (Annotation Comparison)
unavailable
OLGA (Gene List Generator)
unavailable
Gene Annotator (Annotation Comparison)
OLGA (Gene List Generator)
Excel (Download)
MOET (Multi-Ontology Enrichement)
unavailable
GOLF (Gene-Ortholog Location Finder)
unavailable
MOET (Multi-Ontology Enrichement)
GOLF (Gene-Ortholog Location Finder)
x
Send Message
x
Send us a Message
Your email
Message
Send
Submit Data
|
Help
|
Video Tutorials
|
News
|
Publications
|
Download
|
REST API
|
Citing RGD
|
Contact
Home
Search RGD
Grant Resources
Citing RGD
About Us
Contact Us
Data
Genes
Variants
Community Projects
QTLs
Strains
Markers
Genome Information
Ontologies
Cell Lines
References
Download
Submit Data
Analysis & Visualization
OntoMate (Literature Search)
JBrowse (Genome Browser)
Synteny Browser (VCMap)
Variant Visualizer
Multi-Ontology Enrichment (MOET)
Gene-Ortholog Location Finder (GOLF)
InterViewer (Protein-Protein Interactions)
PhenoMiner (Quatitative Phenotypes)
Gene Annotator
OLGA (Gene List Generator)
AllianceMine
GViewer (Genome Viewer)
Diseases
Aging & Age-Related Disease
Cancer & Neoplastic Disease
Cardiovascular Disease
Coronavirus Disease
Developmental Disease
Diabetes
Hematologic Disease
Immune & Inflammatory Disease
Infectious Disease
Liver Disease
Neurological Disease
Obesity & Metabolic Syndrome
Renal Disease
Respiratory Disease
Sensory Organ Disease
Phenotypes & Models
Find Models
Genetic Models
Autism Models
Rat PhenoMiner (Quantitative Phenotypes)
Chinchilla PhenoMiner
Expected Ranges (Quantitative Phenotype)
PhenoMiner Term Comparison
Hybrid Rat Diversity Panel
Phenotypes
Phenotypes in Other Animal Models
Animal Husbandry
Strain Medical Records
Phylogenetics
Strain Availability
Calendar
Rats 101
Submissions
Photo Archive
Pathways
Community
Rat Community Forum
Directory of Rat Laboratories
Video Tutorials
News
RGD Publications
RGD Presentations Archive
Nomenclature Guidelines
Resource Links
Laboratory Resources
Employment Resources
Advanced Search (OLGA)
Ontology Browser
Term:
negative regulation of immune system process
(GO:0002683)
Annotations:
Rat: (582)
Mouse: (638)
Human: (629)
Chinchilla: (489)
Bonobo: (548)
Dog: (579)
Squirrel: (503)
Pig: (559)
Naked Mole-rat: (481)
Green Monkey: (564)
Parent Terms
Term With Siblings
Child Terms
immune system process
+
negative regulation of biological process
+
regulation of immune system process
+
activation of immune response
+
antigen processing and presentation
+
antigen sampling in mucosal-associated lymphoid tissue
+
B cell selection
+
hemocyte differentiation
+
hemocyte proliferation
+
immune effector process
+
immune response
+
immune system development
+
immunological memory process
+
leukocyte activation
+
leukocyte homeostasis
+
leukocyte migration
+
lymphocyte costimulation
+
myeloid cell homeostasis
+
negative regulation of 3'-UTR-mediated mRNA stabilization
negative regulation of action potential
+
negative regulation of border follicle cell delamination
negative regulation of cardiac conduction
negative regulation of cellular pH reduction
+
negative regulation of cellular process
+
negative regulation of circadian rhythm
+
negative regulation of developmental pigmentation
+
negative regulation of developmental process
+
negative regulation of entry of bacterium into host cell
negative regulation of establishment of protein-containing complex localization to telomere
negative regulation of establishment of RNA localization to telomere
negative regulation of excitatory postsynaptic potential
+
negative regulation of fibrinolysis
negative regulation of formation of structure involved in a symbiotic process
+
negative regulation of gene silencing by regulatory ncRNA
+
negative regulation of growth
+
negative regulation of GTPase activity
negative regulation of hemostasis
+
negative regulation of immune system process
+
Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
negative regulation of interphase mitotic telomere clustering
negative regulation of kainate selective glutamate receptor signaling pathway
negative regulation of lipid localization
+
negative regulation of locomotion
+
negative regulation of long-term synaptic depression
negative regulation of long-term synaptic potentiation
negative regulation of membrane depolarization
+
negative regulation of membrane hyperpolarization
negative regulation of membrane repolarization during cardiac muscle cell action potential
+
negative regulation of mitotic telomere tethering at nuclear periphery
negative regulation of multicellular organismal process
+
negative regulation of post-transcriptional gene silencing
+
negative regulation of receptor localization to synapse
negative regulation of receptor-mediated virion attachment to host cell
negative regulation of reproductive process
+
negative regulation of response to stimulus
+
negative regulation of short-term synaptic potentiation
negative regulation of signaling
+
negative regulation of telomerase RNA localization to Cajal body
negative regulation of transformation of host cell by virus
negative regulation of transport
+
negative regulation of viral process
+
positive regulation of immune system process
+
production of molecular mediator of immune response
+
regulation of activated T cell autonomous cell death
+
regulation of activation-induced cell death of T cells
+
regulation of antigen processing and presentation
+
regulation of hemocyte differentiation
+
regulation of hemocyte proliferation
+
regulation of hemopoiesis
+
regulation of immune effector process
+
regulation of immune response
+
regulation of immune system process
+
regulation of leukocyte activation
+
regulation of leukocyte migration
+
regulation of mast cell apoptotic process
+
regulation of mature B cell apoptotic process
+
regulation of neutrophil apoptotic process
+
regulation of tolerance induction
+
somatic diversification of immune receptors
+
T cell selection
+
tolerance induction
+
negative regulation of activated T cell autonomous cell death
negative regulation of activation-induced cell death of T cells
negative regulation of antigen processing and presentation
+
negative regulation of antigen receptor-mediated signaling pathway
+
negative regulation of cytoplasmic pattern recognition receptor signaling pathway
+
negative regulation of erythrocyte clearance
negative regulation of hemocyte differentiation
+
negative regulation of hemocyte proliferation
negative regulation of hemopoiesis
+
negative regulation of immune effector process
+
negative regulation of immune response
+
negative regulation of leukocyte activation
+
negative regulation of leukocyte migration
+
negative regulation of mast cell apoptotic process
negative regulation of peptidoglycan recognition protein signaling pathway
negative regulation of T cell costimulation
+
negative regulation of tolerance induction
+
negative regulation of toll-like receptor 1 signaling pathway
negative regulation of toll-like receptor 10 signaling pathway
negative regulation of toll-like receptor 15 signaling pathway
negative regulation of toll-like receptor 2 signaling pathway
negative regulation of toll-like receptor 4 signaling pathway
negative regulation of toll-like receptor 5 signaling pathway
negative regulation of toll-like receptor 6 signaling pathway
negative regulation of toll-like receptor signaling pathway
+
Synonyms
Exact Synonyms:
down regulation of immune system process ; downregulation of immune system process
Narrow Synonyms:
inhibition of immune system process
Definition Sources:
GOC:add