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Term:
DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228)
Annotations: Rat: (510) Mouse: (562) Human: (533) Chinchilla: (434) Bonobo: (501) Dog: (458) Squirrel: (471) Pig: (488) Naked Mole-rat: (450) Green Monkey: (508)
Parent Terms Term With Siblings Child Terms
DNA-binding transcription activator activity, RNA polymerase II-specific  
A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.
DNA-binding transcription repressor activity, RNA polymerase II-specific  
ligand-modulated transcription activator activity 
nuclear receptor activity +   

Synonyms
Exact Synonyms: RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription ;   transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
Narrow Synonyms: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription ;   RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription ;   RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding ;   RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding ;   RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding ;   RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding ;   RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding ;   copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription ;   distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific ;   metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription
Alternate IDs: GO:0001077 ;   GO:0001205 ;   GO:0001209 ;   GO:0001211 ;   GO:0001212 ;   GO:0001213
Xrefs: Reactome:R-HSA-9856539 "MLXIPL:MLX binds PKLR gene promoter" ;   Reactome:R-HSA-9856546 "MLXIPL:MLX binds FASN gene promoter" ;   Reactome:R-HSA-9856548 "MLXIPL:MLX binds ACACB gene promoter" ;   Reactome:R-HSA-9856549 "MLXIPL:MLX binds ACLY gene promoter" ;   Reactome:R-HSA-9856550 "MLXIPL:MLX binds ACACA gene promoter" ;   Reactome:R-HSA-9856604 "MLXIPL:MLX binds AGPAT1 gene promoter"
Definition Sources: GOC:aruk, GOC:txnOH-2018, PMID:20737563, PMID:27145859

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