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Ontology Browser

Term:
RNA polymerase III general transcription initiation factor activity (GO:0000995)
Annotations: Rat: (11) Mouse: (11) Human: (13) Chinchilla: (10) Bonobo: (11) Dog: (12) Squirrel: (11) Pig: (11) Naked Mole-rat: (11) Green Monkey: (11)
Parent Terms Term With Siblings Child Terms
RNA polymerase I general transcription initiation factor activity  
RNA polymerase II general transcription initiation factor activity  
RNA polymerase III general transcription initiation factor activity  
A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III.

Synonyms
Exact Synonyms: RNA polymerase III general initiation factor activity
Narrow Synonyms: core RNA polymerase III binding transcription factor activity ;   sequence-specific DNA binding RNA polymerase III transcription factor activity
Alternate IDs: GO:0001034
Definition Sources: GOC:txnOH-2018, PMID:12381659, PMID:17977614, PMID:20413673, PMID:27068803, Wikipedia:RNA_polymerase_III

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