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Ontology Browser
Term:
MIT family translocation renal cell carcinoma (EFO:MONDO:0017886)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
renal cell carcinoma +     
adrenal cortex carcinoma +  
collecting duct carcinoma 
cystic renal cell carcinoma 
Kidney Medullary Carcinoma +  
MIT family translocation renal cell carcinoma +  
MiT family translocation renal cell carcinoma (t-RCC) is a rare subtype of renal cell carcinoma with recurrent genetic abnormalities, harboring rearrangements of the TFE3 (Xp11 t-RCC) or TFEB [t(6;11) t-RCC] genes. The t(6;11) t-RCC has distinctive histologic features of biphasic appearance with larger epitheloid and smaller eosinophilic cells. The symptoms are usually non-specific and include hematuria, flank pain, palpable abdominal mass and/or systemic symptoms of anemia, fatigue and fever.
nonpapillary renal cell carcinoma +   
renal cell adenocarcinoma +   
renal pelvis adenocarcinoma 
ureter adenocarcinoma 
Wolffian duct adenocarcinoma 

Synonyms
Exact Synonyms: carcinoma associated with MITF/TFE translocation ;   translocation renal cell carcinoma
Alternate IDs: MONDO:0017886
Xrefs: DOID:0081413 ;   GARD:17446 ;   MEDGEN:1376834 ;   ORDO:319308 ;   SCTID:764694005 ;   UMLS:C4518356
Definition Sources: Orphanet:319308

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