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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
anal canal neuroendocrine neoplasm +  
Combined Lung Carcinoma +  
goblet cell carcinoma 
large cell neuroendocrine carcinoma +  
liver neuroendocrine carcinoma +  
Malignant Adrenal Gland Pheochromocytoma 
medullary thyroid gland carcinoma +  
A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy.
pancreatic endocrine carcinoma +  
papillary follicular thyroid adenocarcinoma 
small cell carcinoma +   
thymic neuroendocrine carcinoma +  
thyroid cancer, nonmedullary, 4 
thyroid cancer, nonmedullary, 5 
vulvar neuroendocrine carcinoma +  

Synonyms
Exact Synonyms: C cell carcinoma ;   MTC ;   carcinoma of parafollicular cell ;   carcinoma, C-cell, malignant ;   medullary carcinoma ;   medullary carcinoma of the thyroid ;   medullary carcinoma of the thyroid gland ;   medullary carcinoma of thyroid ;   medullary carcinoma of thyroid gland ;   parafollicular cell carcinoma
Related Synonyms: THME ;   medullary thyroid cancer (MTC) ;   thyroid cancer, medullary ;   thyroid carcinoma, medullary
Alternate IDs: MONDO:0015277
Xrefs: DOID:3973 ;   GARD:7004 ;   HP:0002865 ;   MEDGEN:66772 ;   MedDRA:10027101 ;   NANDO:2201054 ;   NCI:C3879 ;   ONCOTREE:THME ;   ORDO:1332 ;   SCTID:255032005
External Ontologys: disease_has_location EFO:CL:0000570
Definition Sources: NCIT:C3879

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