A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
Synonyms
Exact Synonyms:
blood coagulation, platelet activation
Alternate IDs:
GO:0030168
Xrefs:
Reactome:R-HSA-392023 "Adrenaline signalling through Alpha-2 adrenergic receptor"
;
Reactome:R-HSA-392170 "ADP signalling through P2Y purinoceptor 12"
;
Reactome:R-HSA-418592 "ADP signalling through P2Y purinoceptor 1"
;
Reactome:R-HSA-76002 "Platelet activation, signaling and aggregation"