A23187 response/sensitivity measurement - Ontology Browser

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A23187 response/sensitivity measurement (CMO:0003659)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)

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chemical response/sensitivity measurement + is-a

A23187 response/sensitivity measurement +

Measurement of an organism's, organ's, tissue's or cell's capacity to respond, such as by a change in activity, state or condition, to A23187, an ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria.

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A23187-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel

Synonyms
Exact Synonyms:	calcimycin response/sensitivity measurement
Xrefs:	CHEBI:3305 ; PMID:22508433
Definition Sources:	MESH:D000001

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