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Ontology Browser
Term:
concentration of BAY 60-4552 at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) (CMO:0003413)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
BAY 60-4552-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel 
blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel +  
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) +  
concentration of BAY 60-4552 at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
A calculated value for the concentration of BAY 60-4552, a small molecule stimulator of soluble guanylate cyclase, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of BAY 60-4552 is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during BAY 60-4552-induced relaxation of the vessel wall (i.e. the maximum effect of BAY 60-4552 which is the minimum contractile energy).
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
concentration of GSK2181236A at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) +  

Synonyms
Exact Synonyms: concentration of Nelociguat at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)
Xrefs: PMID:22783192
Definition Sources: PMID:22783192

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