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Ontology Browser
Term:
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) (CMO:0003409)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel +  
carbachol-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel 
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) +  
concentration of BAY 60-4552 at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
A calculated value for the concentration of carbachol, the ammonium salt that is a slowly hydrolyzed cholinergic agonist that acts at both muscarinic receptors and nicotinic receptors, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of carbachol is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during carbachol-induced relaxation of the vessel wall (i.e. the maximum effect of carbachol which is the minimum contractile energy).
concentration of GSK2181236A at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) +  

Synonyms
Exact Synonyms: concentration of carbamylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) ;   concentration of carbastat at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)
Xrefs: CHEBI:3385 ;   MESH:D002217
Definition Sources: American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed

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