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Term:
logarithm of the concentration of vasoconstrictor at which the force of blood vessel contraction is half the maximum value (Log EC50) (CMO:0002465)
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Parent Terms Term With Siblings Child Terms
calculated blood vessel maximum contractile force measurement +  
concentration of vasoconstrictor at which the force of blood vessel contraction is half the maximum value (EC50) +  
logarithm of the concentration of vasoconstrictor at which the force of blood vessel contraction is half the maximum value (Log EC50) +  
A calculated value for logarithm of the concentration of a vasoconstrictor at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of the stimulus is halfway between the baseline value and the highest achievable value of such stimulus-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value. A vasoconstrictor is any agent or condition that narrows blood vessels by constricting the smooth muscle in the vessel walls.
slope measurement of chemical-induced contraction +  
vasoconstrictor-induced blood vessel contractile force expressed as percent of force at baseline +  

Synonyms
Exact Synonyms: vasoconstrictor Log half maximal effective concentration (Log EC50)
Definition Sources: Collins:Collins_Online_English_Dictionary, Farlex:Farlex_Partner_Medical_Dictionary_2012, http://en.wikipedia.org/wiki/EC50 "Wikipedia" "Wikipedia"

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