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Ontology Browser
Term:
concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (EC50) (CMO:0002462)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (EC50) 
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) +  
concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (EC50) 
A calculated value for the concentration of potassium chloride (KCl) at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of KCl is halfway between the baseline value and the highest achievable value of such KCl-induced contractile energy. Potassium chloride is the salt of the potassium cation (K+) and the chlorine/chloride anion (Cl-). It is used as an eletroylyte replenisher and has mild vasoconstrictive properties when applied directly to blood vessels.
logarithm of the concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (Log EC50) 
potassium chloride-induced blood vessel contractile force expressed as percent of force at baseline 

Synonyms
Exact Synonyms: potassium chloride half maximal effective concentration (EC50)
Related Synonyms: KCl half maximal effective concentration (EC50)
Xrefs: CHEBI:32588
Definition Sources: American_Heritage:The_American_Heritage_Medical_Dictionary_2007, http://en.wikipedia.org/wiki/EC50 "Wikipedia" "Wikipedia", PMID:22031779

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