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Ontology Browser
Term:
logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) (CMO:0001658)
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Parent Terms Term With Siblings Child Terms
concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (EC50) 
logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) 
A calculated value for logarithm of the concentration of angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of AngII is halfway between the baseline value and the highest achievable value of such AngII-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value.
logarithm of the concentration of norepinephrine at which the force of blood vessel contraction is half the maximum value 
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) 
logarithm of the concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (Log EC50) 

Synonyms
Related Synonyms: Ang2 Log half maximal effective concentration ;   AngII Log half maximal effective concentration ;   angiotensin 2 Log half maximal effective concentration ;   angiotensin II Log half maximal effective concentration (EC50)
Xrefs: CHEBI:48432
Definition Sources: Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II "Wikipedia" "Wikipedia", http://en.wikipedia.org/wiki/EC50 "Wikipedia" "Wikipedia", ISBN:978-1416049982

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