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Ontology Browser

Term:
concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (EC50) (CMO:0001657)
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Parent Terms Term With Siblings Child Terms
concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (EC50) 
A calculated value for the concentration of angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of AngII is halfway between the baseline value and the highest achievable value of such AngII-induced contractile energy.
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) +  
concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (EC50) 
logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) 

Synonyms
Related Synonyms: Ang2 half maximal effective concentration ;   AngII half maximal effective concentration ;   angiotensin 2 half maximal effective concentration ;   angiotensin II half maximal effective concentration (EC50)
Xrefs: CHEBI:48432
Definition Sources: Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II "Wikipedia" "Wikipedia", http://en.wikipedia.org/wiki/EC50 "Wikipedia" "Wikipedia", ISBN:978-1416049982

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