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Ontology Browser
Term:
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) (CMO:0000726)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel +  
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) +  
concentration of BAY 60-4552 at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
concentration of GSK2181236A at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) +  
A calculated value for the concentration of sodium nitroprusside (SNP), the red-colored inorganic salt with the formula Na2[Fe(CN)5NO]-2H2O used as a potent vasodilator, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of SNP is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during SNP-induced relaxation of the vessel wall (i.e. the maximum effect of SNP which is the minimum contractile energy).
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel 

Synonyms
Exact Synonyms: sodium nitroprusside half maximal effective concentration (EC50)
Xrefs: CHEBI:29321 ;   CHEBI:9179
Definition Sources: Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/EC50 "Wikipedia" "Wikipedia", http://en.wikipedia.org/wiki/Sodium_nitroprusside "Wikipedia" "Wikipedia", ISBN:978-1416049982

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