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Ontology Browser
Term:
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) (CMO:0000722)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) 
logarithm of the concentration of norepinephrine at which the force of blood vessel contraction is half the maximum value 
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) 
A calculated value for logarithm of the concentration of phenylephrine (PE), the phenylethanolamine with IUPAC name (R)-3-[-1-hydroxy-2-(methylamino)ethyl]phenol and formula C9H13NO2 that acts as a selective alpha1-adrenergic receptor agonist, decongestant and vasoconstrictor, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of PE is halfway between the baseline value and the highest achievable value of such PE-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value.
logarithm of the concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (Log EC50) 

Synonyms
Exact Synonyms: phenylephrine Log half maximal effective concentration (Log EC50)
Xrefs: CHEBI:8093
Definition Sources: Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/EC50 "Wikipedia" "Wikipedia", ISBN:978-1416049982

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