Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
(13R)-13-dihydrocarminomycin 
(1R,2S)-nortilidine +  
(1S,2R)-nortilidine +  
(2S)-2'-hydroxydemethoxymatteucinol 
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(3,5-dihydroxyphenyl)acetic acid 
(5-hydroxyindol-3-yl)acetic acid +   
(6-methoxy-2-naphthyl)acetic acid 
(R)-7-butyl-6,8-dihydroxy-3-[(3E)-pent-3-en-1-yl]-3,4-dihydroisochromen-1-one 
(R)-N-trans-feruloyloctopamine 
1',4-dihydroxymidazolam 
1,1,1,3,3,3-hexafluoropropan-2-ol  
1,2,4-triazole-3-carboxamide +   
1-(3-chlorophenyl)piperazine  
1-hydroxymidazolam +   
1-hydroxymidazolam beta-D-glucuronide  
10,11-trans-dihydroxy-10,11-dihydrocarbamazepine +  
12-demethylmulticaulin 
12-demethylmultiorthoquinone 
12-hydroxynevirapine 
12-methyl-5-dehydroacetylhorminone 
12-methyl-5-dehydrohorminone +  
15-acetoxyorbiculin G 
1alpha-acetoxy-2alpha-hydroxy-6beta,9beta,15-tribenzoyloxy-beta-dihydroagarofuran 
2,3,4-trihydroxbenzophenone 
2,6-dimethylaniline +   
2-formylbenzoic acid 
2-hydroxyibuprofen 
2-methoxyacetaminophen glucuronide 
2-methoxyacetaminophen glucuronide(1-) 
2-methoxyacetaminophen sulfate 
2-methoxyacetaminophen sulfate(1-) 
2-nitroimidazole 
2alpha-acetoxy-1alpha-hydroxy-6beta,9beta,15-tribenzoyloxy-beta-dihydroagarofuran 
3'-hydroxy-4'-methoxydiclofenac 
3'-hydroxydiclofenac 
3,4-dihydroxymandelic acid  
3,5-dinitrosalicylic acid hydrazide 
3-(\{cis-4-[(2-\{[2-(acetylamino)ethyl]disulfanyl\}ethyl)carbamoyl]cyclohexyl\}carbamoyl)pyrazine-2-carboxylic acid 
3-chlorobenzoic acid 
3-hydroxy-2,2-dimethylbutyric acid 
3-hydroxymethylantipyrine 
3-oxociprofloxacin 
4',5-dihydroxydiclofenac 
4'-hydroxy torasemide 
4'-hydroxydiclofenac  
4-(acetylamino)-3-hydroxyphenyl hydrogen sulfate 
4-(acetylamino)-3-hydroxyphenyl sulfate 
4-(methylamino)antipyrine 
4-(trifluoromethyl)phenol 
4-acetamidoantipyrine 
4-aminoantipyrine 
4-aminosalicylic acid  
4-ethoxyaniline +   
4-formylaminoantipyrine 
4-hydroxy-2,6-dimethylaniline 
4-hydroxy-6-methylaniline 
4-hydroxymidazolam +   
4-hydroxymidazolam beta-D-glucuronide 
4-hydroxypropofol 
5'-hydroxyomeprazole  
5-carboxy-2'-deoxyuridine 
5-ethyl-5-methyl-1,3-oxazolidine-2,4-dione +  
5-fluorouridine 5'-monophosphate 
5-hydroxydiclofenac  
5-hydroxydiclofenac quinone imine 
5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid  
5-O-desmethyldonepezil 
6-azauridine +   
6-methyl-1-oxido-pyrazin-1-ium-2-carboxylic acid 
7-hydroxyticlopidine 
acetaminophen O-beta-D-glucosiduronic acid  
acetohydrazide +   
ACT-132577 +   
ACT-333679 +  
adefovir +   
alloxanthine +   
aripiprazole  
atenolol acid 
atenolol-desisopropyl 
azure B  
bedaquiline 
bedaquiline fumarate 
brivanib +  
carbamazepine-10,11-epoxide  
carboxyibuprofen 
carboxyibuprofen(2-) 
caribenol A 
ceftaroline +   
clopidogrel carboxylic acid 
CNDAC +  
cotinine N-oxide 
cyclosporin A metabolite M1 +  
cyclosporin A metabolite M10 
cyclosporin A metabolite M13 
cyclosporin A metabolite M16 +  
cyclosporin A metabolite M17 +  
cyclosporin A metabolite M18 +  
cyclosporin A metabolite M1A 
cyclosporin A metabolite M1cAL 
cyclosporin A metabolite M21 +  
cyclosporin A metabolite M25 
cyclosporin A metabolite M26 
cyclosporin A metabolite M8 +  
cyclosporin A metabolite M9 
cyclosporin A sulfate 
D-cycloserine +   
D617 
desacetylpyramidaglain D 
desloratadine +   
desmethyl loperamide 
desmethyldoxepin +  
desmethylnaproxen  
desmethylnaproxen sulfate 
desmethylnaproxen(1-) 
desmethylranitidine 
Dichotomocej E 
diclofenac beta-D-glucosiduronic acid 
didesethylflurazepam 
dihydrooroxylin A 
dioxoaminopyrine 
DM-4103 
DM-4107 
doxorubicinol 
ethambutol +   
ethambutol dihydrochloride 
ethionamide +   
ethionamide S-oxide 
ethisterone  
fenofibric acid 
glycinexylidide +  
GS-441524 +   
GS-441524 monophosphate 
GS-443902 
hentriacontane +  
hydroxy torasemide 
hydroxyalbendazole 
hydroxyfenbendazole 
Hypnosin 
imidaprilat  
indometacin +   
INDY +  
isoniazide +   
ixazomib +   
levesquamide 
lividomycins +  
lomefloxacin +   
lomefloxacin hydrochloride 
maniladiol 
mevinolinic acid 
monoethylglycinexylidide +   
monomethyl fumarate 
multicaulin 
multiorthoquinone 
N(4)-hydroxycytidine +   
N,N-didesmethylvenlafaxine 
N,N-diethylglycine 
N,O-didesmethylvenlafaxine 
N-acetylsulfamethoxazole 
N-desmethylvenlafaxine 
N-methylthiourea  
nelociguat 
nitrazepam +   
nitrososulfadiazine 
nitrososulfapyridine 
norfentanyl 
nortriptyline  
norverapamil  
O-desethyl candesartan 
O-desmethylvenlafaxine 
omega-hydroxyfinasteride 
orbiculin G +  
oxidopamine  
oxyphenbutazone +   
paliperidone 
paracetamol sulfate +   
perindoprilat 
PF-00835231 +  
phomoxanthone A 
phomoxanthone B 
pisonin B 
pisonivanone 
prednisolone +   
procainamide 4-hydroxylamine 
proglumide +  
promazine sulfoxide 
psilocin +  
pyrazine-2-carboxylic acid  
The parent compound of the class of pyrazinecarboxylic acids, that is pyrazine bearing a single carboxy substituent. The active metabolite of the antitubercular drug pyrazinamide.
pyrazinecarboxamide +   
pyridine N-oxide +   
rac-nortilidine 
ramiprilat  
ranitidine N-oxide 
ranitidine-S-oxide 
ribavirin 5'-diphosphate 
ribavirin 5'-monophosphate 
ribavirin 5'-triphosphate 
ribavirin carboxylic acid 
rifabutin  
rifampicin +   
rifamycin SV +   
rifapentine  
ritalinic acid  
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteinate 
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine 
S-3100-CA +   
S-ethyl-L-cysteine 
SN-38 +   
SN-38 carboxylic acid 
spiraprilat +   
steviolbioside 
sulfadiazine hydroxylamine 
sulfapyridine hydroxylamine 
sulfociprofloxacin 
tedizolid 
tenofovir (anhydrous) +   
teriflunomide  
theophylline +   
torasemide carboxylic acid 
trandolaprilat +   
tubelactomicin A 
uridine +   
viomycin +  
viomycin(3+) +  
WR-1065  
zofenoprilat 

Synonyms
Related Synonyms: 2-Carboxypyrazine ;   2-Pyrazinecarboxylic acid ;   Formula=C5H4N2O2 ;   InChI=1S/C5H4N2O2/c8-5(9)4-3-6-1-2-7-4/h1-3H,(H,8,9) ;   InChIKey=NIPZZXUFJPQHNH-UHFFFAOYSA-N ;   Paradiazinecarboxylic acid ;   Pyrazinemonocarboxylic acid ;   Pyrazinic acid ;   Pyrazinoic acid ;   SMILES=OC(=O)c1cnccn1
Xrefs: CAS:98-97-5 ;   KEGG:C19915
Xref Mesh: MESH:C005296
Xrefs: MetaCyc:PYRAZINOIC-ACID ;   PDBeChem:VGL ;   PMID:19298694 ;   PMID:19963078 ;   PMID:20099263 ;   PMID:20382083 ;   PMID:20429806 ;   PMID:20879713 ;   PMID:21283666 ;   PMID:21775138
Cyclic Relationships: is_conjugate_acid_of CHEBI:71266

paths to the root