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Ontology Browser

Term:
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750)
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Parent Terms Term With Siblings Child Terms
2,2,3,3-tetrahydroxy-2,3-dihydronaphthalene-1,4-dione 
actinodaphnine 
CP-115953 
EC 5.99.1.2 (DNA topoisomerase) inhibitor +   
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor +   
A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
topoisomerase II inhibitor +   
topoisomerase IV inhibitor +   

Synonyms
Related Synonyms: DNA gyrase inhibitor ;   DNA gyrase inhibitors ;   DNA topoisomerase (ATP-hydrolysing) inhibitor ;   DNA topoisomerase (ATP-hydrolysing) inhibitors ;   DNA topoisomerase II inhibitor ;   DNA topoisomerase II inhibitors ;   EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors ;   EC 5.99.1.3 inhibitor ;   EC 5.99.1.3 inhibitors ;   inhibitor of type II topoisomerase
Alternate IDs: CHEBI:132229 ;   CHEBI:50234

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